Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50026972
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265086((+/-)-2-amino-N-(2-(1-methyl-4-(4-(methylthio)benz...)
Affinity DataIC50: 0.950nMAssay Description:Displacement of radiolabeled MCP1 from CCR2 in human PBMC by millipore filter plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265204((+/-)-2-amino-N-(2-(1-methyl-4-(4-(methylthio)benz...)
Affinity DataIC50: 1.80nMAssay Description:Displacement of radiolabeled MCP1 from CCR2 in human PBMC by millipore filter plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265204((+/-)-2-amino-N-(2-(1-methyl-4-(4-(methylthio)benz...)
Affinity DataIC50: 2nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced calcium flux by fluorescence-imaging plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265087((+/-)-2-amino-N-(2-(4-(4-(methylthio)benzylamino)-...)
Affinity DataIC50: 2nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced calcium flux by fluorescence-imaging plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265123((+/-)-3-amino-N-(2-(4-(4-(methylthio)benzylamino)-...)
Affinity DataIC50: 3nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced calcium flux by fluorescence-imaging plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265121((+/-)-N-(2-(4-(4-(methylthio)benzylamino)-1-propyl...)
Affinity DataIC50: 3nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced calcium flux by fluorescence-imaging plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265087((+/-)-2-amino-N-(2-(4-(4-(methylthio)benzylamino)-...)
Affinity DataIC50: 3.40nMAssay Description:Displacement of radiolabeled MCP1 from CCR2 in human PBMC by millipore filter plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265121((+/-)-N-(2-(4-(4-(methylthio)benzylamino)-1-propyl...)
Affinity DataIC50: 3.80nMAssay Description:Displacement of radiolabeled MCP1 from CCR2 in human PBMC by millipore filter plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265203((+/-)-2-amino-N-(2-(1-butyl-4-(4-(methylthio)benza...)
Affinity DataIC50: 4.30nMAssay Description:Displacement of radiolabeled MCP1 from CCR2 in human PBMC by millipore filter plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265122((+/-)-N-(2-(2-(4-(4-(methylthio)benzylamino)-1-pro...)
Affinity DataIC50: 4.80nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265086((+/-)-2-amino-N-(2-(1-methyl-4-(4-(methylthio)benz...)
Affinity DataIC50: 5nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced calcium flux by fluorescence-imaging plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265087((+/-)-2-amino-N-(2-(4-(4-(methylthio)benzylamino)-...)
Affinity DataIC50: 5.40nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265205((+/-)-3-amino-N-(2-(4-(4-(methylthio)benzamido)-1-...)
Affinity DataIC50: 6nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced calcium flux by fluorescence-imaging plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265043((+/-)-2-amino-N-(2-(4-(4-(methylthio)benzylamino)p...)
Affinity DataIC50: 6.10nMAssay Description:Binding affinity to wild type CCR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265123((+/-)-3-amino-N-(2-(4-(4-(methylthio)benzylamino)-...)
Affinity DataIC50: 6.10nMAssay Description:Displacement of radiolabeled MCP1 from CCR2 in human PBMC by millipore filter plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265205((+/-)-3-amino-N-(2-(4-(4-(methylthio)benzamido)-1-...)
Affinity DataIC50: 6.20nMAssay Description:Displacement of radiolabeled MCP1 from CCR2 in human PBMC by millipore filter plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265043((+/-)-2-amino-N-(2-(4-(4-(methylthio)benzylamino)p...)
Affinity DataIC50: 6.30nMAssay Description:Displacement of radiolabeled MCP1 from CCR2 in human PBMC by millipore filter plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265043((+/-)-2-amino-N-(2-(4-(4-(methylthio)benzylamino)p...)
Affinity DataIC50: 7nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced calcium flux by fluorescence-imaging plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265120((+/-)-2-amino-N-(2-(1-butyl-4-(4-(methylthio)benzy...)
Affinity DataIC50: 7.90nMAssay Description:Displacement of radiolabeled MCP1 from CCR2 in human PBMC by millipore filter plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265121((+/-)-N-(2-(4-(4-(methylthio)benzylamino)-1-propyl...)
Affinity DataIC50: 8nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265122((+/-)-N-(2-(2-(4-(4-(methylthio)benzylamino)-1-pro...)
Affinity DataIC50: 8.70nMAssay Description:Displacement of radiolabeled MCP1 from CCR2 in human PBMC by millipore filter plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255735((+/-)-2-amino-N-(2-(4-(4-(methylthio)benzamido)pip...)
Affinity DataIC50: 12nMAssay Description:Binding affinity to wild type CCR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265120((+/-)-2-amino-N-(2-(1-butyl-4-(4-(methylthio)benzy...)
Affinity DataIC50: 13nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced calcium flux by fluorescence-imaging plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265203((+/-)-2-amino-N-(2-(1-butyl-4-(4-(methylthio)benza...)
Affinity DataIC50: 13nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced calcium flux by fluorescence-imaging plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265203((+/-)-2-amino-N-(2-(1-butyl-4-(4-(methylthio)benza...)
Affinity DataIC50: 17.5nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265044((+/-)-2-amino-N-(2-(4-(4-chlorobenzylamino)piperid...)
Affinity DataIC50: 19nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced calcium flux by fluorescence-imaging plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265120((+/-)-2-amino-N-(2-(1-butyl-4-(4-(methylthio)benzy...)
Affinity DataIC50: 19nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265122((+/-)-N-(2-(2-(4-(4-(methylthio)benzylamino)-1-pro...)
Affinity DataIC50: 21nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced calcium flux by fluorescence-imaging plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265044((+/-)-2-amino-N-(2-(4-(4-chlorobenzylamino)piperid...)
Affinity DataIC50: 21.5nMAssay Description:Displacement of radiolabeled MCP1 from CCR2 in human PBMC by millipore filter plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265205((+/-)-3-amino-N-(2-(4-(4-(methylthio)benzamido)-1-...)
Affinity DataIC50: 25nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265123((+/-)-3-amino-N-(2-(4-(4-(methylthio)benzylamino)-...)
Affinity DataIC50: 26nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265086((+/-)-2-amino-N-(2-(1-methyl-4-(4-(methylthio)benz...)
Affinity DataIC50: 27.5nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255735((+/-)-2-amino-N-(2-(4-(4-(methylthio)benzamido)pip...)
Affinity DataIC50: 28nMAssay Description:Displacement of radiolabeled MCP1 from CCR2 in human PBMC by millipore filter plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265204((+/-)-2-amino-N-(2-(1-methyl-4-(4-(methylthio)benz...)
Affinity DataIC50: 38.5nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255735((+/-)-2-amino-N-(2-(4-(4-(methylthio)benzamido)pip...)
Affinity DataIC50: 75nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced calcium flux by fluorescence-imaging plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265085((+/-)-N-(2-(4-(4-(methylthio)benzylamino)piperidin...)
Affinity DataIC50: 97nMAssay Description:Displacement of radiolabeled MCP1 from CCR2 in human PBMC by millipore filter plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255735((+/-)-2-amino-N-(2-(4-(4-(methylthio)benzamido)pip...)
Affinity DataIC50: 109nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265084((+/-)-2-amino-N-(2-(4-(4-(ethylthio)benzylamino)pi...)
Affinity DataIC50: 123nMAssay Description:Displacement of radiolabeled MCP1 from CCR2 in human PBMC by millipore filter plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265043((+/-)-2-amino-N-(2-(4-(4-(methylthio)benzylamino)p...)
Affinity DataIC50: 285nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265164((+/-)-N-(2-(1-acetyl-4-(4-(methylthio)benzylamino)...)
Affinity DataIC50: 463nMAssay Description:Displacement of radiolabeled MCP1 from CCR2 in human PBMC by millipore filter plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265085((+/-)-N-(2-(4-(4-(methylthio)benzylamino)piperidin...)
Affinity DataIC50: 510nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced calcium flux by fluorescence-imaging plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265042((+/-)-2-amino-N-(2-(2-(4-(methylthio)benzylamino)c...)
Affinity DataIC50: 1.18E+3nMAssay Description:Displacement of radiolabeled MCP1 from CCR2 in human PBMC by millipore filter plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed