Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50022595
TargetSerine/threonine-protein kinase Chk1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50514649(CHEMBL3990456)
Affinity DataKi:  0.490nMAssay Description:Binding affinity to human recombinant CHK1 assessed as inhibition constant using PLARTLSVAGLPGKK as substrate incubated for 20 min in presence of NAD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCyclin-dependent kinase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50514649(CHEMBL3990456)
Affinity DataKi:  9.90nMAssay Description:Binding affinity to CDK1 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50514649(CHEMBL3990456)
Affinity DataKi:  16nMAssay Description:Binding affinity to VEGFR2 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50514649(CHEMBL3990456)
Affinity DataIC50: 20nMAssay Description:Inhibition of Fms (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetTyrosine-protein kinase Yes(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50514649(CHEMBL3990456)
Affinity DataIC50: 29nMAssay Description:Inhibition of Yes (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetFibroblast growth factor receptor 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50514649(CHEMBL3990456)
Affinity DataIC50: 47nMAssay Description:Inhibition of FGFR3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetAurora kinase A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50514649(CHEMBL3990456)
Affinity DataIC50: 47nMAssay Description:Inhibition of Aurora A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50514649(CHEMBL3990456)
Affinity DataKi:  47nMAssay Description:Binding affinity to CHK2 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50514649(CHEMBL3990456)
Affinity DataIC50: 51nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50514649(CHEMBL3990456)
Affinity DataIC50: 80nMAssay Description:Inhibition of Ret (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed