Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 2797
TargetGenome polyprotein [1424-1463]/[1502-1685](WNV)
University of Queensland

LigandPNGBDBM24732((2S)-6-amino-N-[(1S)-5-amino-1-{[(2S)-5-carbamimid...)
Affinity DataKi:  6nM ΔG°:  -48.8kJ/mole IC50: 32nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2008
Entry Details Article
PubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](WNV)
University of Queensland

LigandPNGBDBM24731((2S)-6-amino-N-[(1S)-5-amino-1-{[(2S)-5-carbamimid...)
Affinity DataKi:  9nM ΔG°:  -47.8kJ/mole IC50: 51nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2008
Entry Details Article
PubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](WNV)
University of Queensland

LigandPNGBDBM24734((2S)-6-amino-N-[(1S)-5-amino-1-{[(2S)-5-carbamimid...)
Affinity DataKi:  11nM ΔG°:  -47.3kJ/mole IC50: 60nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2008
Entry Details Article
PubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](WNV)
University of Queensland

LigandPNGBDBM24746((2S)-6-amino-N-[(1S)-4-amino-1-{[(2S)-5-carbamimid...)
Affinity DataKi:  13nM ΔG°:  -46.8kJ/mole IC50: 73nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2008
Entry Details Article
PubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](WNV)
University of Queensland

LigandPNGBDBM24739((2S)-6-amino-N-[(1S)-5-amino-1-{[(2S)-5-carbamimid...)
Affinity DataKi:  19nM ΔG°:  -45.8kJ/mole IC50: 107nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2008
Entry Details Article
PubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](WNV)
University of Queensland

LigandPNGBDBM24733((2S)-6-amino-N-[(1S)-5-amino-1-{[(2S)-5-carbamimid...)
Affinity DataKi:  20nM ΔG°:  -45.7kJ/mole IC50: 112nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2008
Entry Details Article
PubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](WNV)
University of Queensland

LigandPNGBDBM24735((2S)-6-amino-N-[(1S)-5-amino-1-{[(2S)-5-carbamimid...)
Affinity DataKi:  26nM ΔG°:  -45.0kJ/mole IC50: 146nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2008
Entry Details Article
PubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](WNV)
University of Queensland

LigandPNGBDBM24741((2S)-6-amino-N-[(2S)-5-carbamimidamido-1-oxopentan...)
Affinity DataKi:  28nM ΔG°:  -44.8kJ/mole IC50: 154nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2008
Entry Details Article
PubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](WNV)
University of Queensland

LigandPNGBDBM24736(benzyl N-[(1S)-5-amino-1-{[(1S)-5-amino-1-{[(2S)-5...)
Affinity DataKi:  40nM ΔG°:  -43.9kJ/mole IC50: 222nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2008
Entry Details Article
PubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](WNV)
University of Queensland

LigandPNGBDBM24728((2S)-6-amino-N-[(1S)-5-amino-1-{[(2S)-5-carbamimid...)
Affinity DataKi:  41nM ΔG°:  -43.9kJ/mole IC50: 231nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2008
Entry Details Article
PubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](WNV)
University of Queensland

LigandPNGBDBM24744((2S)-N-[(1S)-5-amino-1-{[(2S)-5-carbamimidamido-1-...)
Affinity DataKi:  44nM ΔG°:  -43.7kJ/mole IC50: 245nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2008
Entry Details Article
PubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](WNV)
University of Queensland

LigandPNGBDBM24742((2S)-6-amino-2-[(2S)-5-amino-2-(1-phenylacetamido)...)
Affinity DataKi:  46nM ΔG°:  -43.6kJ/mole IC50: 255nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2008
Entry Details Article
PubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](WNV)
University of Queensland

LigandPNGBDBM24737((2S)-6-amino-N-[(1S)-5-amino-1-{[(2S)-5-carbamimid...)
Affinity DataKi:  49nM ΔG°:  -43.4kJ/mole IC50: 271nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2008
Entry Details Article
PubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](WNV)
University of Queensland

LigandPNGBDBM24748((2S)-2-[(2S)-6-amino-2-(1-phenylacetamido)hexanami...)
Affinity DataKi:  53nM ΔG°:  -43.2kJ/mole IC50: 297nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2008
Entry Details Article
PubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](WNV)
University of Queensland

LigandPNGBDBM24745((2S)-6-amino-N-[(1S)-4-carbamimidamido-1-{[(2S)-5-...)
Affinity DataKi:  58nM ΔG°:  -43.0kJ/mole IC50: 325nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2008
Entry Details Article
PubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](WNV)
University of Queensland

LigandPNGBDBM24738((2S)-6-amino-N-[(1S)-5-amino-1-{[(2S)-5-carbamimid...)
Affinity DataKi:  81nM ΔG°:  -42.1kJ/mole IC50: 454nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2008
Entry Details Article
PubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](WNV)
University of Queensland

LigandPNGBDBM24730((2S)-6-amino-2-[(2S)-6-amino-2-[(2E)-3-phenylprop-...)
Affinity DataKi:  104nM ΔG°:  -41.5kJ/mole IC50: 580nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2008
Entry Details Article
PubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](WNV)
University of Queensland

LigandPNGBDBM24743((2S)-6-amino-N-[(2S)-5-carbamimidamido-1-oxopentan...)
Affinity DataKi:  111nM ΔG°:  -41.3kJ/mole IC50: 619nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2008
Entry Details Article
PubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](WNV)
University of Queensland

LigandPNGBDBM24740((2S)-6-amino-N-[(1S)-5-amino-1-{[(2S)-5-carbamimid...)
Affinity DataKi:  160nM ΔG°:  -40.3kJ/mole IC50: 891nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2008
Entry Details Article
PubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](WNV)
University of Queensland

LigandPNGBDBM24747((2S)-6-amino-N-[(1S)-1-{[(2S)-5-carbamimidamido-1-...)
Affinity DataKi:  2.07E+3nM ΔG°:  -33.7kJ/mole IC50: 1.16E+4nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2008
Entry Details Article
PubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](WNV)
University of Queensland

LigandPNGBDBM24749((2S)-6-amino-N-[(1S)-5-amino-1-{[(2S)-1-(1H-indol-...)
Affinity DataKi:  4.60E+3nM ΔG°:  -31.7kJ/mole IC50: 2.57E+4nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2008
Entry Details Article
PubMed