Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50027012
TargetCannabinoid receptor 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50247086(Chlorphrifos oxon | diethyl 3,5,6-trichloropyridin...)
Affinity DataKd:  0.860nMAssay Description:Displacement of [3H]CP-55940 from CB1 receptor in mouse brain at 100 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50132717(Isopropyl dodecylfluorophosphonate | isopropyl dod...)
Affinity DataEC50:  500nMAssay Description:Agonist activity at CB1 receptor in mouse brain membrane assessed as stimulation of GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMonoglyceride lipase(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50247050(4-cyanophenyl ethyl dodecylphosphonate | CHEMBL462...)
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of MAGL-mediated 2-arachidonoylglycerol hydrolysis in mouse brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50247048(methyl icosylphosphonofluoridate | CHEMBL462609)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of FAAH-mediated [3H]anandamide hydrolysis in mouse brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMonoglyceride lipase(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50247049(ethyl 3,5,6-trichloropyridin-2-yl dodecylphosphona...)
Affinity DataIC50: 0.140nMAssay Description:Inhibition of MAGL-mediated 2-arachidonoylglycerol hydrolysis in mouse brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50247052(2-Nonylsulfanyl-4H-benzo[1,3,2]dioxaphosphinine 2-...)
Affinity DataIC50: 0.150nMAssay Description:Inhibition of FAAH-mediated [3H]anandamide hydrolysis in mouse brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMonoglyceride lipase(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50247051(isopropyl 4-nitrophenyl dodecylphosphonate | CHEMB...)
Affinity DataIC50: 0.280nMAssay Description:Inhibition of MAGL-mediated 2-arachidonoylglycerol hydrolysis in mouse brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMonoglyceride lipase(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50247052(2-Nonylsulfanyl-4H-benzo[1,3,2]dioxaphosphinine 2-...)
Affinity DataIC50: 0.310nMAssay Description:Inhibition of MAGL-mediated 2-arachidonoylglycerol hydrolysis in mouse brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMonoglyceride lipase(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50132717(Isopropyl dodecylfluorophosphonate | isopropyl dod...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of MAGL-mediated 2-arachidonoylglycerol hydrolysis in mouse brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50247008(octane-1-sulfonyl fluoride | CHEMBL499569)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of FAAH-mediated [3H]anandamide hydrolysis in mouse brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50132717(Isopropyl dodecylfluorophosphonate | isopropyl dod...)
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]CP-55940 from CB1 receptor in mouse brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50132715(Dodecanesulfonyl fluoride | dodecane-1-sulfonyl fl...)
Affinity DataIC50: 2nMAssay Description:Inhibition of FAAH-mediated [3H]anandamide hydrolysis in mouse brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMonoglyceride lipase(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50247048(methyl icosylphosphonofluoridate | CHEMBL462609)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of MAGL-mediated 2-arachidonoylglycerol hydrolysis in mouse brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50247086(Chlorphrifos oxon | diethyl 3,5,6-trichloropyridin...)
Affinity DataIC50: 3nMAssay Description:Displacement of [3H]CP-55940 from mouse CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50132717(Isopropyl dodecylfluorophosphonate | isopropyl dod...)
Affinity DataIC50: 3nMAssay Description:Inhibition of FAAH-mediated [3H]anandamide hydrolysis in mouse brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50247051(isopropyl 4-nitrophenyl dodecylphosphonate | CHEMB...)
Affinity DataIC50: 3nMAssay Description:Inhibition of FAAH-mediated [3H]anandamide hydrolysis in mouse brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50247050(4-cyanophenyl ethyl dodecylphosphonate | CHEMBL462...)
Affinity DataIC50: 4nMAssay Description:Displacement of [3H]CP-55940 from CB1 receptor in mouse brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50132715(Dodecanesulfonyl fluoride | dodecane-1-sulfonyl fl...)
Affinity DataIC50: 7nMAssay Description:Displacement of [3H]CP-55940 from CB1 receptor in mouse brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMonoglyceride lipase(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50247086(Chlorphrifos oxon | diethyl 3,5,6-trichloropyridin...)
Affinity DataIC50: 10nMAssay Description:Inhibition of MAGL-mediated 2-arachidonoylglycerol hydrolysis in mouse brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50247086(Chlorphrifos oxon | diethyl 3,5,6-trichloropyridin...)
Affinity DataIC50: 10nMAssay Description:Displacement of [3H]CP-55940 from CB1 receptor in mouse brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50247050(4-cyanophenyl ethyl dodecylphosphonate | CHEMBL462...)
Affinity DataIC50: 12nMAssay Description:Inhibition of FAAH-mediated [3H]anandamide hydrolysis in mouse brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50247051(isopropyl 4-nitrophenyl dodecylphosphonate | CHEMB...)
Affinity DataIC50: 12nMAssay Description:Displacement of [3H]CP-55940 from CB1 receptor in mouse brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50247049(ethyl 3,5,6-trichloropyridin-2-yl dodecylphosphona...)
Affinity DataIC50: 14nMAssay Description:Displacement of [3H]CP-55940 from CB1 receptor in mouse brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50247048(methyl icosylphosphonofluoridate | CHEMBL462609)
Affinity DataIC50: 20nMAssay Description:Displacement of [3H]CP-55940 from CB1 receptor in mouse brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50247086(Chlorphrifos oxon | diethyl 3,5,6-trichloropyridin...)
Affinity DataIC50: 40nMAssay Description:Inhibition of FAAH-mediated [3H]anandamide hydrolysis in mouse brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50247049(ethyl 3,5,6-trichloropyridin-2-yl dodecylphosphona...)
Affinity DataIC50: 42nMAssay Description:Inhibition of FAAH-mediated [3H]anandamide hydrolysis in mouse brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMonoglyceride lipase(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50247050(4-cyanophenyl ethyl dodecylphosphonate | CHEMBL462...)
Affinity DataIC50: 70nMAssay Description:Inhibition of MAGL-mediated [14C]1-oleoylglycerol hydrolysis in mouse brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMonoglyceride lipase(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50247008(octane-1-sulfonyl fluoride | CHEMBL499569)
Affinity DataIC50: 140nMAssay Description:Inhibition of MAGL-mediated 2-arachidonoylglycerol hydrolysis in mouse brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMonoglyceride lipase(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50132715(Dodecanesulfonyl fluoride | dodecane-1-sulfonyl fl...)
Affinity DataIC50: 200nMAssay Description:Inhibition of MAGL-mediated 2-arachidonoylglycerol hydrolysis in mouse brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50240416(diethyl 4-nitrophenyl phosphate | paraoxon | O,O-d...)
Affinity DataIC50: 540nMAssay Description:Inhibition of FAAH-mediated [3H]anandamide hydrolysis in mouse brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50240416(diethyl 4-nitrophenyl phosphate | paraoxon | O,O-d...)
Affinity DataIC50: 1.20E+3nMAssay Description:Displacement of [3H]CP-55940 from CB1 receptor in mouse brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50247008(octane-1-sulfonyl fluoride | CHEMBL499569)
Affinity DataIC50: 1.30E+3nMAssay Description:Displacement of [3H]CP-55940 from CB1 receptor in mouse brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMonoglyceride lipase(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50240416(diethyl 4-nitrophenyl phosphate | paraoxon | O,O-d...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of MAGL-mediated 2-arachidonoylglycerol hydrolysis in mouse brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50247086(Chlorphrifos oxon | diethyl 3,5,6-trichloropyridin...)
Affinity DataIC50: 2.50E+4nMAssay Description:Displacement of [3H]CP-55940 from mouse CB1 receptor expressed in HEK293 cells in presence of mouse brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed