Compile Data Set for Download or QSAR
Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 50038679
TargetC-C chemokine receptor type 3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50264210(2-(Azepan-1-ylcarbonyl)-N-{(3-exo)-8-[(6-fluoro-2-...)
Affinity DataIC50: 12nMAssay Description:Antagonist activity at CCR3 receptor expressed in mouse B300-19 cells assessed as inhibition of eotaxin-induced calcium influx by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50264161(N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)methyl]-8-azabi...)
Affinity DataIC50: 13nMAssay Description:Antagonist activity at CCR3 receptor expressed in mouse B300-19 cells assessed as inhibition of eotaxin-induced calcium influx by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50264142(N-(8-((6-fluoronaphthalen-2-yl)methyl)-8-azabicycl...)
Affinity DataIC50: 20nMAssay Description:Antagonist activity at CCR3 receptor expressed in mouse B300-19 cells assessed as inhibition of eotaxin-induced calcium influx by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50264142(N-(8-((6-fluoronaphthalen-2-yl)methyl)-8-azabicycl...)
Affinity DataIC50: 20nMAssay Description:Antagonist activity at CCR3 receptor expressed in mouse B300-19 cells assessed as inhibition of eotaxin-induced calcium influx by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50264157(N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)methyl]-8-azabi...)
Affinity DataIC50: 23nMAssay Description:Antagonist activity at CCR3 receptor expressed in mouse B300-19 cells assessed as inhibition of eotaxin-induced calcium influx by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50264212(N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)methyl]-8-azabi...)
Affinity DataIC50: 23nMAssay Description:Antagonist activity at CCR3 receptor expressed in mouse B300-19 cells assessed as inhibition of eotaxin-induced calcium influx by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50264144(N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)methyl]-8-azabi...)
Affinity DataIC50: 29nMAssay Description:Antagonist activity at CCR3 receptor expressed in mouse B300-19 cells assessed as inhibition of eotaxin-induced calcium influx by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50264208(N-Cyclohexyl-N'-{(3-exo)-8-[(6-fluoro-2-naphthyl)-...)
Affinity DataIC50: 44nMAssay Description:Antagonist activity at CCR3 receptor expressed in mouse B300-19 cells assessed as inhibition of eotaxin-induced calcium influx by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50264191(N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)methyl]-8-azabi...)
Affinity DataIC50: 57nMAssay Description:Antagonist activity at CCR3 receptor expressed in mouse B300-19 cells assessed as inhibition of eotaxin-induced calcium influx by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50264162(N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)methyl]-8-azabi...)
Affinity DataIC50: 85nMAssay Description:Antagonist activity at CCR3 receptor expressed in mouse B300-19 cells assessed as inhibition of eotaxin-induced calcium influx by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50264155(N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)methyl]-8-azabi...)
Affinity DataIC50: 89nMAssay Description:Antagonist activity at CCR3 receptor expressed in mouse B300-19 cells assessed as inhibition of eotaxin-induced calcium influx by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50377956(CHEMBL1744356)
Affinity DataIC50: 93nMAssay Description:Antagonist activity at CCR3 receptor expressed in mouse B300-19 cells assessed as inhibition of eotaxin-induced calcium influx by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50264160(N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)methyl]-8-azabi...)
Affinity DataIC50: 98nMAssay Description:Antagonist activity at CCR3 receptor expressed in mouse B300-19 cells assessed as inhibition of eotaxin-induced calcium influx by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50264206(2-(Cyclohexyloxy)-N-{(3-exo)-8-[(6-fluoro-2-naphth...)
Affinity DataIC50: 118nMAssay Description:Antagonist activity at CCR3 receptor expressed in mouse B300-19 cells assessed as inhibition of eotaxin-induced calcium influx by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50264211(N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)methyl]-8-azabi...)
Affinity DataIC50: 131nMAssay Description:Antagonist activity at CCR3 receptor expressed in mouse B300-19 cells assessed as inhibition of eotaxin-induced calcium influx by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50264205(N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)methyl]-8-azabi...)
Affinity DataIC50: 217nMAssay Description:Antagonist activity at CCR3 receptor expressed in mouse B300-19 cells assessed as inhibition of eotaxin-induced calcium influx by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50264156(N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)methyl]-8-azabi...)
Affinity DataIC50: 221nMAssay Description:Antagonist activity at CCR3 receptor expressed in mouse B300-19 cells assessed as inhibition of eotaxin-induced calcium influx by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50264209(N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)methyl]-8-azabi...)
Affinity DataIC50: 225nMAssay Description:Antagonist activity at CCR3 receptor expressed in mouse B300-19 cells assessed as inhibition of eotaxin-induced calcium influx by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50264207(N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)methyl]-8-azabi...)
Affinity DataIC50: 279nMAssay Description:Antagonist activity at CCR3 receptor expressed in mouse B300-19 cells assessed as inhibition of eotaxin-induced calcium influx by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50264142(N-(8-((6-fluoronaphthalen-2-yl)methyl)-8-azabicycl...)
Affinity DataIC50: 400nMAssay Description:Inhibition of human CYP2D6 by fluorescence technique in presence of NADPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50264142(N-(8-((6-fluoronaphthalen-2-yl)methyl)-8-azabicycl...)
Affinity DataIC50: 400nMAssay Description:Inhibition of human CYP2D6 by fluorescence technique in presence of NADPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50264158(N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)methyl]-8-azabi...)
Affinity DataIC50: 482nMAssay Description:Antagonist activity at CCR3 receptor expressed in mouse B300-19 cells assessed as inhibition of eotaxin-induced calcium influx by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50264206(2-(Cyclohexyloxy)-N-{(3-exo)-8-[(6-fluoro-2-naphth...)
Affinity DataIC50: 580nMAssay Description:Inhibition of human CYP2D6 by fluorescence technique in presence of NADPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50264143(N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)methyl]-8-azabi...)
Affinity DataIC50: 613nMAssay Description:Antagonist activity at CCR3 receptor expressed in mouse B300-19 cells assessed as inhibition of eotaxin-induced calcium influx by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50264159(N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)methyl]-8-azabi...)
Affinity DataIC50: 679nMAssay Description:Antagonist activity at CCR3 receptor expressed in mouse B300-19 cells assessed as inhibition of eotaxin-induced calcium influx by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50264144(N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)methyl]-8-azabi...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human CYP2D6 by fluorescence technique in presence of NADPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50264155(N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)methyl]-8-azabi...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human CYP2D6 by fluorescence technique in presence of NADPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50377956(CHEMBL1744356)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of human CYP2D6 by fluorescence technique in presence of NADPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50264208(N-Cyclohexyl-N'-{(3-exo)-8-[(6-fluoro-2-naphthyl)-...)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of human CYP2D6 by fluorescence technique in presence of NADPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50264210(2-(Azepan-1-ylcarbonyl)-N-{(3-exo)-8-[(6-fluoro-2-...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human CYP2D6 by fluorescence technique in presence of NADPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50264191(N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)methyl]-8-azabi...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human CYP2D6 by fluorescence technique in presence of NADPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50264157(N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)methyl]-8-azabi...)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of human CYP2D6 by fluorescence technique in presence of NADPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50264161(N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)methyl]-8-azabi...)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of human CYP2D6 by fluorescence technique in presence of NADPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50264158(N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)methyl]-8-azabi...)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of human CYP2D6 by fluorescence technique in presence of NADPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50264209(N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)methyl]-8-azabi...)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of human CYP2D6 by fluorescence technique in presence of NADPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50264159(N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)methyl]-8-azabi...)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of human CYP2D6 by fluorescence technique in presence of NADPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50264160(N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)methyl]-8-azabi...)
Affinity DataIC50: 1.83E+4nMAssay Description:Inhibition of human CYP2D6 by fluorescence technique in presence of NADPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50264142(N-(8-((6-fluoronaphthalen-2-yl)methyl)-8-azabicycl...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50264142(N-(8-((6-fluoronaphthalen-2-yl)methyl)-8-azabicycl...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50264142(N-(8-((6-fluoronaphthalen-2-yl)methyl)-8-azabicycl...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50264142(N-(8-((6-fluoronaphthalen-2-yl)methyl)-8-azabicycl...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50264211(N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)methyl]-8-azabi...)
Affinity DataIC50: 2.35E+4nMAssay Description:Inhibition of human CYP2D6 by fluorescence technique in presence of NADPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50264162(N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)methyl]-8-azabi...)
Affinity DataIC50: 2.67E+4nMAssay Description:Inhibition of human CYP2D6 by fluorescence technique in presence of NADPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50264212(N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)methyl]-8-azabi...)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of human CYP2D6 by fluorescence technique in presence of NADPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50264212(N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)methyl]-8-azabi...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50264212(N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)methyl]-8-azabi...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50264212(N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)methyl]-8-azabi...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50264212(N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)methyl]-8-azabi...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed