Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50000750
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009407(CHEMBL311800 | But-3-enoic acid 8-[2-(4-hydroxy-6-...)
Affinity DataIC50: 2.90nMAssay Description:In vitro inhibitory activity against rat liver HMG-CoA reductase enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009411(CHEMBL312626 | 6-{2-[8-(4-Fluoro-benzyloxy)-2,6-di...)
Affinity DataIC50: 4.70nMAssay Description:In vitro inhibitory activity against rat liver HMG-CoA reductase enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009413(CHEMBL3085466 | Phenyl-acetic acid 8-[2-(4-hydroxy...)
Affinity DataIC50: 19nMAssay Description:In vitro inhibitory activity against rat liver HMG-CoA reductase enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009414(CHEMBL311047 | 6-[2-(8-Benzyloxy-2,6-dimethyl-1,2,...)
Affinity DataIC50: 27nMAssay Description:In vitro inhibitory activity against rat liver HMG-CoA reductase enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009409(CHEMBL309410 | 6-{2-[8-(4-Chloro-benzyloxy)-2,6-di...)
Affinity DataIC50: 170nMAssay Description:In vitro inhibitory activity against rat liver HMG-CoA reductase enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009408(CHEMBL310601 | Acetic acid 8-[2-(4-hydroxy-6-oxo-t...)
Affinity DataIC50: 269nMAssay Description:In vitro inhibitory activity against rat liver HMG-CoA reductase enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009415(CHEMBL81519 | 6-{2-[2,6-Dimethyl-8-(2-methyl-allyl...)
Affinity DataIC50: 360nMAssay Description:In vitro inhibitory activity against rat liver HMG-CoA reductase enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009410(CHEMBL310877 | 6-[2-(8-Allyloxy-2,6-dimethyl-1,2,6...)
Affinity DataIC50: 370nMAssay Description:In vitro inhibitory activity against rat liver HMG-CoA reductase enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009412(CHEMBL81138 | 4-Hydroxy-6-[2-(8-methoxy-2,6-dimeth...)
Affinity DataIC50: 2.81E+3nMAssay Description:In vitro inhibitory activity against rat liver HMG-CoA reductase enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed