Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50000752
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009426(2,2-Dimethyl-butyric acid 4-benzylcarbamoyloxy-8-[...)
Affinity DataIC50: 5nMAssay Description:In vitro ability to inhibit solubilized, partially purified, rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009423(2,2-Dimethyl-butyric acid 8-[2-(4-hydroxy-6-oxo-te...)
Affinity DataIC50: 6nMAssay Description:In vitro ability to inhibit solubilized, partially purified, rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50406550(CHEMBL2114188 | CHEMBL3349570)
Affinity DataIC50: 6nMAssay Description:In vitro ability to inhibit solubilized, partially purified, rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009429(2,2-Dimethyl-butyric acid 4-(diphenyl-phosphinoylo...)
Affinity DataIC50: 6nMAssay Description:In vitro ability to inhibit solubilized, partially purified, rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50406549(CHEMBL2115196 | CHEMBL3349562)
Affinity DataIC50: 6.60nMAssay Description:In vitro ability to inhibit solubilized, partially purified, rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50003240(2,2-Dimethyl-butyric acid 8-[2-(4-hydroxy-6-oxo-te...)
Affinity DataIC50: 12nMAssay Description:In vitro ability to inhibit solubilized, partially purified, rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009420(2,2-Dimethyl-butyric acid 8-[2-(4-hydroxy-6-oxo-te...)
Affinity DataIC50: 13nMAssay Description:In vitro ability to inhibit solubilized, partially purified, rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009422(2,2-Dimethyl-butyric acid 4-dibenzylcarbamoyloxy-8...)
Affinity DataIC50: 16nMAssay Description:In vitro ability to inhibit solubilized, partially purified, rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50003235(CHEMBL333443 | BDBM50226269 | 2-Methyl-butyric aci...)
Affinity DataIC50: 18nMAssay Description:In vitro ability to inhibit solubilized, partially purified, rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009425(2,2-Dimethyl-butyric acid 8-[2-(4-hydroxy-6-oxo-te...)
Affinity DataIC50: 34nMAssay Description:In vitro ability to inhibit solubilized, partially purified, rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009418(2,2-Dimethyl-butyric acid 5-[2-(4-hydroxy-6-oxo-te...)
Affinity DataIC50: 35nMAssay Description:In vitro ability to inhibit solubilized, partially purified, rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009419(2,2-Dimethyl-butyric acid 4-hydroxy-8-[2-(4-hydrox...)
Affinity DataIC50: 41nMAssay Description:In vitro ability to inhibit solubilized, partially purified, rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009417(2,2-Dimethyl-butyric acid 4-hydroxy-8-[2-(4-hydrox...)
Affinity DataIC50: 49nMAssay Description:In vitro ability to inhibit solubilized, partially purified, rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009427(2,2-Dimethyl-butyric acid 8-[2-(4-hydroxy-6-oxo-te...)
Affinity DataIC50: 59nMAssay Description:In vitro ability to inhibit solubilized, partially purified, rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009424(2,2-Dimethyl-butyric acid 4-hydroxy-8-[2-(4-hydrox...)
Affinity DataIC50: 289nMAssay Description:In vitro ability to inhibit solubilized, partially purified, rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009421(2,2-Dimethyl-butyric acid 1-(2-{2-[4-(tert-butyl-d...)
Affinity DataIC50: 1.70E+3nMAssay Description:In vitro ability to inhibit solubilized, partially purified, rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009428(2,2-Dimethyl-butyric acid 4-hydroxy-1-{6-hydroxy-2...)
Affinity DataIC50: 2.80E+3nMAssay Description:In vitro ability to inhibit solubilized, partially purified, rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed