Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50035974
TargetAromatase(Human)
Tohoku College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50332808((8R,9S,10S,13S,14S)-10-(hydroxymethyl)-13-methyl-2...)
Affinity DataKi:  13nMAssay Description:Binding affinity for human placental microsome cytochrome P450 19A1 with 1 uM [1-beta-3H]-androstenedioneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50332807((8R,9S,10R,13S,14S)-10,13-dimethyl-2,3,7,8,9,10,11...)
Affinity DataKi:  37nMAssay Description:Binding affinity for human placental microsome cytochrome P450 19A1 with 1 uM [1-beta-3H]-androstenedioneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50009437(CHEMBL440691 | 10-Hydroxymethyl-13-methyl-2,3,6,7,...)
Affinity DataKi:  170nMAssay Description:Binding affinity for human placental microsome cytochrome P450 19A1 with 1 uM [1-beta-3H]-androstenedioneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50009430(CHEMBL83422 | 16-Bromo-10,13-dimethyl-1,2,3,6,7,8,...)
Affinity DataKi:  228nMAssay Description:Binding affinity for human placental microsome cytochrome P450 19A1 with 1 uM [1-beta-3H]-androstenedioneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50332808((8R,9S,10S,13S,14S)-10-(hydroxymethyl)-13-methyl-2...)
Affinity DataIC50: 270nMAssay Description:Inhibition of 1 uM [1-beta-3H]-androstenedione binding to human placental microsome Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50009436(CHEMBL309656 | Acetic acid 13-methyl-17-oxo-1,2,3,...)
Affinity DataKi:  289nMAssay Description:Binding affinity for human placental microsome cytochrome P450 19A1 with 1 uM [1-beta-3H]-androstenedioneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50240798(CHEMBL132530 | 4-hyroxyandrostenedione | (8R,9S,10...)
Affinity DataIC50: 410nMAssay Description:Inhibition of 1 uM [1-beta-3H]-androstenedione binding to human placental microsome Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50009435(CHEMBL83835 | 10-Difluoromethyl-13-methyl-1,2,3,6,...)
Affinity DataKi:  443nMAssay Description:Binding affinity for human placental microsome cytochrome P450 19A1 with 1 uM [1-beta-3H]-androstenedioneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50009431(CHEMBL81134 | 16-Bromo-10,13-dimethyl-1,2,3,6,7,8,...)
Affinity DataKi:  455nMAssay Description:Binding affinity for human placental microsome cytochrome P450 19A1 with 1 uM [1-beta-3H]-androstenedioneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50332807((8R,9S,10R,13S,14S)-10,13-dimethyl-2,3,7,8,9,10,11...)
Affinity DataIC50: 530nMAssay Description:Inhibition of 1 uM [1-beta-3H]-androstenedione binding to human placental microsome Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50009434(CHEMBL439950 | 10,13-Dimethyl-2,3,6,7,8,9,10,11,12...)
Affinity DataKi:  830nMAssay Description:Binding affinity for human placental microsome cytochrome P450 19A1 with 1 uM [1-beta-3H]-androstenedioneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50009435(CHEMBL83835 | 10-Difluoromethyl-13-methyl-1,2,3,6,...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of 1 uM [1-beta-3H]-androstenedione binding to human placental microsome Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50009437(CHEMBL440691 | 10-Hydroxymethyl-13-methyl-2,3,6,7,...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of 1 uM [1-beta-3H]-androstenedione binding to human placental microsome Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50009436(CHEMBL309656 | Acetic acid 13-methyl-17-oxo-1,2,3,...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of 1 uM [1-beta-3H]-androstenedione binding to human placental microsome Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50009430(CHEMBL83422 | 16-Bromo-10,13-dimethyl-1,2,3,6,7,8,...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of 1 uM [1-beta-3H]-androstenedione binding to human placental microsome Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50009431(CHEMBL81134 | 16-Bromo-10,13-dimethyl-1,2,3,6,7,8,...)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of 1 uM [1-beta-3H]-androstenedione binding to human placental microsome Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50009434(CHEMBL439950 | 10,13-Dimethyl-2,3,6,7,8,9,10,11,12...)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of 1 uM [1-beta-3H]-androstenedione binding to human placental microsome Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50009433(CHEMBL82981 | 10-(1-Hydroxy-prop-2-ynyl)-13-methyl...)
Affinity DataKi:  7.75E+3nMAssay Description:Binding affinity for human placental microsome cytochrome P450 19A1 with 1 uM [1-beta-3H]-androstenedioneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50406551(CHEMBL2112309)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of 1 uM [1-beta-3H]-androstenedione binding to human placental microsome Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50009442(CHEMBL311077 | Acetic acid 10-acetoxymethyl-13-met...)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of 1 uM [1-beta-3H]-androstenedione binding to human placental microsome Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50009440(CHEMBL443530 | Acetic acid 17-hydroxy-13-methyl-1,...)
Affinity DataIC50: 4.40E+4nMAssay Description:Inhibition of 1 uM [1-beta-3H]-androstenedione binding to human placental microsome Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50009433(CHEMBL82981 | 10-(1-Hydroxy-prop-2-ynyl)-13-methyl...)
Affinity DataIC50: 6.20E+4nMAssay Description:Inhibition of 1 uM [1-beta-3H]-androstenedione binding to human placental microsome Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50009438(CHEMBL81255 | Acetic acid 10-hydroxymethyl-13-meth...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of 1 uM [1-beta-3H]-androstenedione binding to human placental microsome Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed