Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50027040
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50264232(2-(3-(6-hydroxynaphthalen-2-yl)propanamido)benzoic...)
Affinity DataIC50: 24nMAssay Description:Displacement of [3H]nicotinic acid from human GPR109A receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50264233(2-(3-(6-aminonaphthalen-2-yl)propanamido)benzoic a...)
Affinity DataIC50: 34nMAssay Description:Displacement of [3H]nicotinic acid from human GPR109A receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50264234(2-(3-(6-formylnaphthalen-2-yl)propanamido)benzoic ...)
Affinity DataIC50: 55nMAssay Description:Displacement of [3H]nicotinic acid from human GPR109A receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50264231(2-(3-(6-methoxynaphthalen-2-yl)propanamido)benzoic...)
Affinity DataIC50: 87nMAssay Description:Displacement of [3H]nicotinic acid from human GPR109A receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM23515(pyridine-3-carboxylic acid | CHEMBL573 | [5, 6-3H]...)
Affinity DataIC50: 130nMAssay Description:Displacement of [3H]nicotinic acid from human GPR109A receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM23518(2-[3-(naphthalen-2-yl)propanamido]benzoic acid | C...)
Affinity DataIC50: 140nMAssay Description:Displacement of [3H]nicotinic acid from human GPR109A receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50264232(2-(3-(6-hydroxynaphthalen-2-yl)propanamido)benzoic...)
Affinity DataEC50:  380nMAssay Description:Agonist activity at human GPR109A receptor expressed in CHO-K1 cells by [35S]GTPgammaS guanine nucleotide exchange assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50264233(2-(3-(6-aminonaphthalen-2-yl)propanamido)benzoic a...)
Affinity DataEC50:  540nMAssay Description:Agonist activity at human GPR109A receptor expressed in CHO-K1 cells by [35S]GTPgammaS guanine nucleotide exchange assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50264234(2-(3-(6-formylnaphthalen-2-yl)propanamido)benzoic ...)
Affinity DataEC50:  940nMAssay Description:Agonist activity at human GPR109A receptor expressed in CHO-K1 cells by [35S]GTPgammaS guanine nucleotide exchange assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM23518(2-[3-(naphthalen-2-yl)propanamido]benzoic acid | C...)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at human GPR109A receptor expressed in CHO-K1 cells by [35S]GTPgammaS guanine nucleotide exchange assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50264188(2-(2-(4-tert-butylphenoxy)acetamido)benzoic acid |...)
Affinity DataIC50: 1.20E+3nMAssay Description:Displacement of [3H]nicotinic acid from human GPR109A receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50264188(2-(2-(4-tert-butylphenoxy)acetamido)benzoic acid |...)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at human GPR109A receptor expressed in CHO-K1 cells by [35S]GTPgammaS guanine nucleotide exchange assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM23515(pyridine-3-carboxylic acid | CHEMBL573 | [5, 6-3H]...)
Affinity DataEC50:  1.40E+3nMAssay Description:Agonist activity at human GPR109A receptor expressed in CHO-K1 cells by [35S]GTPgammaS guanine nucleotide exchange assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM23517(CHEMBL228244 | 2-[2-(4-methoxyphenoxy)acetamido]be...)
Affinity DataEC50:  1.25E+4nMAssay Description:Agonist activity at human GPR109A receptor expressed in CHO-K1 cells by [35S]GTPgammaS guanine nucleotide exchange assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed