Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50027140
TargetCholinesterase(Human)
European Research Centre For Drug Discovery and Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50265253((S)-2-amino-3-(1H-indol-3-yl)-N-(2-(1,2,3,4-tetrah...)
Affinity DataKi:  1.33nMAssay Description:Inhibition of human recombinant BChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
European Research Centre For Drug Discovery and Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM8971(CHEMBL129108 | N-[8-(1,2,3,4-tetrahydroacridin-9-y...)
Affinity DataKi:  1.65nMAssay Description:Inhibition of human recombinant BChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
European Research Centre For Drug Discovery and Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50265256((S)-1-(2-(1,2,3,4-tetrahydroacridin-9-ylamino)ethy...)
Affinity DataKi:  1.77nMAssay Description:Inhibition of human recombinant BChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
European Research Centre For Drug Discovery and Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50265252((S)-tert-butyl 3-(1H-indol-3-yl)-1-oxo-1-(2-(1,2,3...)
Affinity DataKi:  1.87nMAssay Description:Inhibition of human recombinant BChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
European Research Centre For Drug Discovery and Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50265255((S)-2-amino-N1,N5-bis(2-(1,2,3,4-tetrahydroacridin...)
Affinity DataKi:  6.21nMAssay Description:Inhibition of human recombinant AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
European Research Centre For Drug Discovery and Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50265256((S)-1-(2-(1,2,3,4-tetrahydroacridin-9-ylamino)ethy...)
Affinity DataKi:  6.75nMAssay Description:Inhibition of human recombinant AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
European Research Centre For Drug Discovery and Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataKi:  7nMAssay Description:Inhibition of human recombinant BChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCholinesterase(Human)
European Research Centre For Drug Discovery and Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50265254((S)-tert-butyl 1,5-dioxo-1,5-bis(2-(1,2,3,4-tetrah...)
Affinity DataKi:  12.6nMAssay Description:Inhibition of human recombinant BChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
European Research Centre For Drug Discovery and Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50265254((S)-tert-butyl 1,5-dioxo-1,5-bis(2-(1,2,3,4-tetrah...)
Affinity DataKi:  15.4nMAssay Description:Inhibition of human recombinant AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
European Research Centre For Drug Discovery and Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50265255((S)-2-amino-N1,N5-bis(2-(1,2,3,4-tetrahydroacridin...)
Affinity DataKi:  25.1nMAssay Description:Inhibition of human recombinant BChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
European Research Centre For Drug Discovery and Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM8971(CHEMBL129108 | N-[8-(1,2,3,4-tetrahydroacridin-9-y...)
Affinity DataKi:  27.9nMAssay Description:Inhibition of human recombinant AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
European Research Centre For Drug Discovery and Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataKi:  36nMAssay Description:Inhibition of human recombinant AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Human)
European Research Centre For Drug Discovery and Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50265252((S)-tert-butyl 3-(1H-indol-3-yl)-1-oxo-1-(2-(1,2,3...)
Affinity DataKi:  130nMAssay Description:Inhibition of human recombinant AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
European Research Centre For Drug Discovery and Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50265251((S)-2-amino-3-(1H-indol-3-yl)-N-(3-oxo-3-(1,2,3,4-...)
Affinity DataKi:  173nMAssay Description:Inhibition of human recombinant BChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
European Research Centre For Drug Discovery and Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50265194((S)-2-amino-3-(1H-indol-3-yl)-N-(2-oxo-2-(1,2,3,4-...)
Affinity DataKi:  251nMAssay Description:Inhibition of human recombinant BChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
European Research Centre For Drug Discovery and Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50265191((S)-2-amino-3-(naphthalen-2-yl)-N-(2-oxo-2-(1,2,3,...)
Affinity DataKi:  252nMAssay Description:Inhibition of human recombinant BChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
European Research Centre For Drug Discovery and Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50265253((S)-2-amino-3-(1H-indol-3-yl)-N-(2-(1,2,3,4-tetrah...)
Affinity DataKi:  280nMAssay Description:Inhibition of human recombinant AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
European Research Centre For Drug Discovery and Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50265250((S)-tert-butyl 3-(1H-indol-3-yl)-1-oxo-1-(3-oxo-3-...)
Affinity DataKi:  443nMAssay Description:Inhibition of human recombinant BChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
European Research Centre For Drug Discovery and Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50265192((S)-N-(2-oxo-2-(1,2,3,4-tetrahydroacridin-9-ylamin...)
Affinity DataKi:  580nMAssay Description:Inhibition of human recombinant BChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
European Research Centre For Drug Discovery and Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50265193((S)-2-amino-N-(2-oxo-2-(1,2,3,4-tetrahydroacridin-...)
Affinity DataKi:  708nMAssay Description:Inhibition of human recombinant BChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
European Research Centre For Drug Discovery and Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50265152((S)-2-(methylamino)-N-(2-oxo-2-(1,2,3,4-tetrahydro...)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of human recombinant BChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
European Research Centre For Drug Discovery and Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50265249((S)-3-(1H-indol-3-yl)-2-(methylamino)-N-(2-oxo-2-(...)
Affinity DataKi:  1.76E+3nMAssay Description:Inhibition of human recombinant BChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
European Research Centre For Drug Discovery and Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50265193((S)-2-amino-N-(2-oxo-2-(1,2,3,4-tetrahydroacridin-...)
Affinity DataKi:  1.91E+3nMAssay Description:Inhibition of human recombinant AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
European Research Centre For Drug Discovery and Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50265194((S)-2-amino-3-(1H-indol-3-yl)-N-(2-oxo-2-(1,2,3,4-...)
Affinity DataKi:  2.21E+3nMAssay Description:Inhibition of human recombinant AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
European Research Centre For Drug Discovery and Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50265249((S)-3-(1H-indol-3-yl)-2-(methylamino)-N-(2-oxo-2-(...)
Affinity DataKi:  3.33E+3nMAssay Description:Inhibition of human recombinant AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
European Research Centre For Drug Discovery and Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50265192((S)-N-(2-oxo-2-(1,2,3,4-tetrahydroacridin-9-ylamin...)
Affinity DataKi:  4.13E+3nMAssay Description:Inhibition of human recombinant AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
European Research Centre For Drug Discovery and Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50265152((S)-2-(methylamino)-N-(2-oxo-2-(1,2,3,4-tetrahydro...)
Affinity DataKi:  6.32E+3nMAssay Description:Inhibition of human recombinant AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
European Research Centre For Drug Discovery and Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50265250((S)-tert-butyl 3-(1H-indol-3-yl)-1-oxo-1-(3-oxo-3-...)
Affinity DataKi:  7.97E+3nMAssay Description:Inhibition of human recombinant AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
European Research Centre For Drug Discovery and Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50265191((S)-2-amino-3-(naphthalen-2-yl)-N-(2-oxo-2-(1,2,3,...)
Affinity DataKi:  1.12E+4nMAssay Description:Inhibition of human recombinant AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
European Research Centre For Drug Discovery and Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50265251((S)-2-amino-3-(1H-indol-3-yl)-N-(3-oxo-3-(1,2,3,4-...)
Affinity DataKi:  3.40E+4nMAssay Description:Inhibition of human recombinant AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed