Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50038689
TargetBile acid receptor(Human)
Graduate School of The Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50274241(4-[1-[3-(3-Methyl-benzyloxy)-phenyl]-methylidene]-...)
Affinity DataEC50:  5.15E+3nMAssay Description:Agonist activity at FXR assessed as activation by cell based luciferase transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Graduate School of The Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50274328(4-(3-(3-fluorobenzyloxy)benzylidene)-1-phenylpyraz...)
Affinity DataEC50:  4.79E+3nMAssay Description:Agonist activity at FXR assessed as activation by cell based luciferase transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Graduate School of The Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50274329(4-(3-(3-(trifluoromethyl)benzyloxy)benzylidene)-1-...)
Affinity DataEC50:  6.92E+3nMAssay Description:Agonist activity at FXR assessed as activation by cell based luciferase transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Graduate School of The Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50274330(4-(3-(4-(trifluoromethyl)benzyloxy)benzylidene)-1-...)
Affinity DataEC50:  2.04E+3nMAssay Description:Agonist activity at FXR assessed as activation by cell based luciferase transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Graduate School of The Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50274331(4-[1-[3-(3-Methyl-benzyloxy)-phenyl]-methylidene]-...)
Affinity DataEC50:  5.37E+3nMAssay Description:Agonist activity at FXR assessed as activation by cell based luciferase transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Graduate School of The Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50274383(1-(4-Fluoro-benzoyl)-4-[1-[3-(3-methyl-benzyloxy)-...)
Affinity DataEC50:  1.86E+3nMAssay Description:Agonist activity at FXR assessed as activation by cell based luciferase transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Graduate School of The Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50274435(4-[1-[3-(3-Methyl-benzyloxy)-phenyl]-methylidene]-...)
Affinity DataEC50:  2.40E+3nMAssay Description:Agonist activity at FXR assessed as activation by cell based luciferase transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Graduate School of The Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50274436(4-(4-(benzyloxy)benzylidene)-1-benzoylpyrazolidine...)
Affinity DataEC50:  3.98E+3nMAssay Description:Agonist activity at FXR assessed as activation by cell based luciferase transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Graduate School of The Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50274545(4-(4-(benzyloxy)benzylidene)-1-(furan-2-carbonyl)p...)
Affinity DataEC50:  3.31E+3nMAssay Description:Agonist activity at FXR assessed as activation by cell based luciferase transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Graduate School of The Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50274546(4-(4-(benzyloxy)benzylidene)-1,2-diphenylpyrazolid...)
Affinity DataEC50:  6.31E+3nMAssay Description:Agonist activity at FXR assessed as activation by cell based luciferase transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Graduate School of The Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50274547(diethyl 2-(4-(benzyloxy)benzylidene)malonate | CHE...)
Affinity DataEC50:  6.17E+3nMAssay Description:Agonist activity at FXR assessed as activation by cell based luciferase transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Graduate School of The Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50274585(4-(3-nitrobenzylidene)-1,2-diphenylpyrazolidine-3,...)
Affinity DataEC50:  4.27E+3nMAssay Description:Agonist activity at FXR assessed as activation by cell based luciferase transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Graduate School of The Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM21674(Chenodeoxycholic Acid | CDCA | (4R)-4-[(1S,2S,5R,7...)
Affinity DataEC50:  6.31E+3nMAssay Description:Agonist activity at FXR assessed as activation by cell based luciferase transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)