Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50027284
TargetBombesin receptor subtype-3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275737(6-methoxy-2-(pyridin-4-ylmethylthio)-1H-benzo[d]im...)
Affinity DataEC50: >3.20E+4nMAssay Description:Agonist activity at recombinant BRS-3 receptor expressed in baculovirus-transduced HEK293 cells assessed as intracellular calcium mobilization by FLI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBombesin receptor subtype-3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275786(2-(1-(6-chlorobenzo[d][1,3]dioxol-5-yl)propan-2-yl...)
Affinity DataEC50:  350nMAssay Description:Agonist activity at recombinant BRS-3 receptor expressed in baculovirus-transduced HEK293 cells assessed as intracellular calcium mobilization by FLI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBombesin receptor subtype-3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275785(2-(2-(6-chlorobenzo[d][1,3]dioxol-5-yl)vinyl)-6-me...)
Affinity DataEC50: >3.20E+4nMAssay Description:Agonist activity at recombinant BRS-3 receptor expressed in baculovirus-transduced HEK293 cells assessed as intracellular calcium mobilization by FLI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBombesin receptor subtype-3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275784(2-(2-(6-chlorobenzo[d][1,3]dioxol-5-yl)ethyl)-6-me...)
Affinity DataEC50:  210nMAssay Description:Agonist activity at recombinant BRS-3 receptor expressed in baculovirus-transduced HEK293 cells assessed as intracellular calcium mobilization by FLI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBombesin receptor subtype-3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275783(2-((6-chlorobenzo[d][1,3]dioxol-5-yloxy)methyl)-6-...)
Affinity DataEC50:  510nMAssay Description:Agonist activity at recombinant BRS-3 receptor expressed in baculovirus-transduced HEK293 cells assessed as intracellular calcium mobilization by FLI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBombesin receptor subtype-3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275782(N-((6-chlorobenzo[d][1,3]dioxol-5-yl)methyl)-6-met...)
Affinity DataEC50: >3.20E+4nMAssay Description:Agonist activity at recombinant BRS-3 receptor expressed in baculovirus-transduced HEK293 cells assessed as intracellular calcium mobilization by FLI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBombesin receptor subtype-3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275740(6-chloro-N-(6-methoxy-1H-benzo[d]imidazol-2-yl)ben...)
Affinity DataEC50: >3.20E+4nMAssay Description:Agonist activity at recombinant BRS-3 receptor expressed in baculovirus-transduced HEK293 cells assessed as intracellular calcium mobilization by FLI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBombesin receptor subtype-3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275739(2-((6-chlorobenzo[d][1,3]dioxol-5-yl)methylthio)-6...)
Affinity DataEC50:  380nMAssay Description:Agonist activity at recombinant BRS-3 receptor expressed in baculovirus-transduced HEK293 cells assessed as intracellular calcium mobilization by FLI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBombesin receptor subtype-3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275738(3-((6-methoxy-1H-benzo[d]imidazol-2-ylthio)methyl)...)
Affinity DataEC50: >3.20E+4nMAssay Description:Agonist activity at recombinant BRS-3 receptor expressed in baculovirus-transduced HEK293 cells assessed as intracellular calcium mobilization by FLI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBombesin receptor subtype-3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50240509(6-methoxy-2-((4-methoxy-3,5-dimethylpyridin-2-yl)m...)
Affinity DataEC50:  3.90E+3nMAssay Description:Agonist activity at recombinant BRS-3 receptor expressed in baculovirus-transduced HEK293 cells assessed as intracellular calcium mobilization by FLI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuromedin-B receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275902(D-Phe-Gln-Trp-Ala-Val-b-Ala-His-Phe-Nle-NH2 | CHEM...)
Affinity DataEC50:  0.550nMAssay Description:Agonist activity at recombinant neuromedin B receptor expressed in baculovirus-transduced HEK293 cells assessed as intracellular calcium mobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGastrin-releasing peptide receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275902(D-Phe-Gln-Trp-Ala-Val-b-Ala-His-Phe-Nle-NH2 | CHEM...)
Affinity DataEC50:  0.0600nMAssay Description:Agonist activity at recombinant gastrin releasing peptide receptor expressed in baculovirus-transduced HEK293 cells assessed as intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBombesin receptor subtype-3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275902(D-Phe-Gln-Trp-Ala-Val-b-Ala-His-Phe-Nle-NH2 | CHEM...)
Affinity DataEC50:  3.90nMAssay Description:Agonist activity at recombinant BRS-3 receptor expressed in baculovirus-transduced HEK293 cells assessed as intracellular calcium mobilization by FLI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBombesin receptor subtype-3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275901(2-((6-chlorobenzo[d][1,3]dioxol-5-yloxy)methyl)-6-...)
Affinity DataEC50: >3.20E+4nMAssay Description:Agonist activity at recombinant BRS-3 receptor expressed in baculovirus-transduced HEK293 cells assessed as intracellular calcium mobilization by FLI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBombesin receptor subtype-3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275844(6-chloro-2-((6-chlorobenzo[d][1,3]dioxol-5-yloxy)m...)
Affinity DataEC50: >3.20E+4nMAssay Description:Agonist activity at recombinant BRS-3 receptor expressed in baculovirus-transduced HEK293 cells assessed as intracellular calcium mobilization by FLI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBombesin receptor subtype-3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275843(2-((6-chlorobenzo[d][1,3]dioxol-5-yloxy)methyl)-6-...)
Affinity DataEC50:  240nMAssay Description:Agonist activity at recombinant BRS-3 receptor expressed in baculovirus-transduced HEK293 cells assessed as intracellular calcium mobilization by FLI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBombesin receptor subtype-3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275842(6-chloro-2-((6-chlorobenzo[d][1,3]dioxol-5-yloxy)m...)
Affinity DataEC50:  570nMAssay Description:Agonist activity at recombinant BRS-3 receptor expressed in baculovirus-transduced HEK293 cells assessed as intracellular calcium mobilization by FLI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBombesin receptor subtype-3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275841(2-(2-(6-chlorobenzo[d][1,3]dioxol-5-yl)ethyl)-5-me...)
Affinity DataEC50: >3.20E+4nMAssay Description:Agonist activity at recombinant BRS-3 receptor expressed in baculovirus-transduced HEK293 cells assessed as intracellular calcium mobilization by FLI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBombesin receptor subtype-3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275840(2-(2-(6-chlorobenzo[d][1,3]dioxol-5-yl)ethyl)-5-me...)
Affinity DataEC50: >3.20E+4nMAssay Description:Agonist activity at recombinant BRS-3 receptor expressed in baculovirus-transduced HEK293 cells assessed as intracellular calcium mobilization by FLI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBombesin receptor subtype-3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275839(2-(2-(6-chlorobenzo[d][1,3]dioxol-5-yl)ethyl)-6-me...)
Affinity DataEC50: >3.20E+4nMAssay Description:Agonist activity at recombinant BRS-3 receptor expressed in baculovirus-transduced HEK293 cells assessed as intracellular calcium mobilization by FLI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBombesin receptor subtype-3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275787(2-(2-(6-chlorobenzo[d][1,3]dioxol-5-yl)ethyl)-6-me...)
Affinity DataEC50: >3.20E+4nMAssay Description:Agonist activity at recombinant BRS-3 receptor expressed in baculovirus-transduced HEK293 cells assessed as intracellular calcium mobilization by FLI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBombesin receptor subtype-3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50241343(H-168/68 | 5-methoxy-2-(2-(4-methoxy-3,5-dimethylp...)
Affinity DataEC50:  1.40E+4nMAssay Description:Agonist activity at recombinant BRS-3 receptor expressed in baculovirus-transduced HEK293 cells assessed as intracellular calcium mobilization by FLI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBombesin receptor subtype-3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275689(2-(3,4-difluorobenzylthio)-6-methoxy-1H-benzo[d]im...)
Affinity DataEC50: >3.20E+4nMAssay Description:Agonist activity at recombinant BRS-3 receptor expressed in baculovirus-transduced HEK293 cells assessed as intracellular calcium mobilization by FLI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBombesin receptor subtype-3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275735(2-(3,5-dimethoxybenzylthio)-6-methoxy-1H-benzo[d]i...)
Affinity DataEC50:  1.60E+3nMAssay Description:Agonist activity at recombinant BRS-3 receptor expressed in baculovirus-transduced HEK293 cells assessed as intracellular calcium mobilization by FLI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBombesin receptor subtype-3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275736(6-methoxy-2-(naphthalen-2-ylmethylthio)-1H-benzo[d...)
Affinity DataEC50: >3.20E+4nMAssay Description:Agonist activity at recombinant BRS-3 receptor expressed in baculovirus-transduced HEK293 cells assessed as intracellular calcium mobilization by FLI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBombesin receptor subtype-3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275902(D-Phe-Gln-Trp-Ala-Val-b-Ala-His-Phe-Nle-NH2 | CHEM...)
Affinity DataKi:  0.360nMAssay Description:Binding affinity to BRS-3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGastrin-releasing peptide receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275902(D-Phe-Gln-Trp-Ala-Val-b-Ala-His-Phe-Nle-NH2 | CHEM...)
Affinity DataKi:  0.990nMAssay Description:Binding affinity to gastrin releasing peptide receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuromedin-B receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275902(D-Phe-Gln-Trp-Ala-Val-b-Ala-His-Phe-Nle-NH2 | CHEM...)
Affinity DataKi:  8.90nMAssay Description:Binding affinity to neuromedin B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed