Compile Data Set for Download or QSAR
Report error Found 68 Enz. Inhib. hit(s) with all data for entry = 50027352
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM84637(NSC_54562 | CHEMBL240773 | QUINPIROLE | CAS_85760-...)
Affinity DataEC50:  2.90nMAssay Description:Intrinsic activity at human D3 receptor expressed in CHO dhfr- cells assessed as inhibition of forskolin-induced cAMP releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274355(N-[N'-(4-Ethynylcyclohex-3-en-1-yl)-N'-propyl-4-am...)
Affinity DataEC50:  1.60nMAssay Description:Intrinsic activity at human D3 receptor expressed in CHO dhfr- cells by [3H]thymidine incorporation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM84637(NSC_54562 | CHEMBL240773 | QUINPIROLE | CAS_85760-...)
Affinity DataEC50:  2.10nMAssay Description:Intrinsic activity at human D3 receptor expressed in CHO dhfr- cells by [3H]thymidine incorporation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274407(N-[4-[4-(4-Biphenyl)triazol-1-yl]butyl]-N-propyl-N...)
Affinity DataEC50:  3.10nMAssay Description:Intrinsic activity at human D3 receptor expressed in CHO dhfr- cells assessed as inhibition of forskolin-induced cAMP releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274407(N-[4-[4-(4-Biphenyl)triazol-1-yl]butyl]-N-propyl-N...)
Affinity DataEC50:  2.60nMAssay Description:Intrinsic activity at human D3 receptor expressed in CHO dhfr- cells by [3H]thymidine incorporation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085331((4-Ethynyl-cyclohex-3-enyl)-dipropyl-amine | 4-eth...)
Affinity DataEC50:  7.70nMAssay Description:Intrinsic activity at human D3 receptor expressed in CHO dhfr- cells assessed as inhibition of forskolin-induced cAMP releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274355(N-[N'-(4-Ethynylcyclohex-3-en-1-yl)-N'-propyl-4-am...)
Affinity DataEC50:  2.10nMAssay Description:Intrinsic activity at human D3 receptor expressed in CHO dhfr- cells assessed as inhibition of forskolin-induced cAMP releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085331((4-Ethynyl-cyclohex-3-enyl)-dipropyl-amine | 4-eth...)
Affinity DataEC50:  4.40nMAssay Description:Intrinsic activity at human D3 receptor expressed in CHO dhfr- cells by [3H]thymidine incorporation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50240560(Biphenyl-4-carboxylic acid {4-[(5-hydroxy-1,2,3,4-...)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]spiperone from human D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274355(N-[N'-(4-Ethynylcyclohex-3-en-1-yl)-N'-propyl-4-am...)
Affinity DataKi:  0.210nMAssay Description:Displacement of [3H]spiperone from human D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274355(N-[N'-(4-Ethynylcyclohex-3-en-1-yl)-N'-propyl-4-am...)
Affinity DataKi:  0.780nMAssay Description:Displacement of [3H]spiperone from human wild type D3 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274407(N-[4-[4-(4-Biphenyl)triazol-1-yl]butyl]-N-propyl-N...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]spiperone from human D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274407(N-[4-[4-(4-Biphenyl)triazol-1-yl]butyl]-N-propyl-N...)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]spiperone from human wild type D3 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50020222(CHEMBL285755 | 7-Dipropylamino-5,6,7,8-tetrahydro-...)
Affinity DataKi:  3.60nMAssay Description:Displacement of [3H]spiperone from human wild type D3 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274355(N-[N'-(4-Ethynylcyclohex-3-en-1-yl)-N'-propyl-4-am...)
Affinity DataKi:  4.30nMAssay Description:Displacement of [3H]spiperone from human D4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274262(N-[N'-Propyl-N'-[4-(2-trimethylsilylethynyl)cycloh...)
Affinity DataKi:  4.40nMAssay Description:Displacement of [3H]spiperone from human D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM55121(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
Affinity DataKi:  6.20nMAssay Description:Displacement of [3H]spiperone from human D4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274356(N-[4-[4-(4-Biphenyl)triazol-1-yl]butyl]-N-propyl-N...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]spiperone from human D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274355(N-[N'-(4-Ethynylcyclohex-3-en-1-yl)-N'-propyl-4-am...)
Affinity DataKi:  40nMAssay Description:Displacement of [3H]spiperone from human D2long receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274355(N-[N'-(4-Ethynylcyclohex-3-en-1-yl)-N'-propyl-4-am...)
Affinity DataKi:  43nMAssay Description:Displacement of [3H]spiperone from human D2short receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274262(N-[N'-Propyl-N'-[4-(2-trimethylsilylethynyl)cycloh...)
Affinity DataKi:  69nMAssay Description:Displacement of [3H]spiperone from human D4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM55121(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
Affinity DataKi:  72nMAssay Description:Displacement of [3H]spiperone from human wild type D3 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274408(N-[4-(4-Methyltriazol-1-yl)butyl]-N-propyl-N-(4-pr...)
Affinity DataKi:  100nMAssay Description:Displacement of [3H]spiperone from human D4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274411(N-[(N'-(4-Cyclohexyl)-N'-propyl)aminobutyl]-4-biph...)
Affinity DataKi:  140nMAssay Description:Displacement of [3H]spiperone from human D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274357(N-[4-[4-(4-Biphenyl)triazol-1-yl]butyl]-N-propyl-N...)
Affinity DataKi:  150nMAssay Description:Displacement of [3H]spiperone from human D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274407(N-[4-[4-(4-Biphenyl)triazol-1-yl]butyl]-N-propyl-N...)
Affinity DataKi:  170nMAssay Description:Displacement of [3H]spiperone from human D2short receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274357(N-[4-[4-(4-Biphenyl)triazol-1-yl]butyl]-N-propyl-N...)
Affinity DataKi:  180nMAssay Description:Displacement of [3H]spiperone from human D2short receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085331((4-Ethynyl-cyclohex-3-enyl)-dipropyl-amine | 4-eth...)
Affinity DataKi:  190nMAssay Description:Displacement of [3H]spiperone from human wild type D3 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274407(N-[4-[4-(4-Biphenyl)triazol-1-yl]butyl]-N-propyl-N...)
Affinity DataKi:  190nMAssay Description:Displacement of [3H]spiperone from human D4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274357(N-[4-[4-(4-Biphenyl)triazol-1-yl]butyl]-N-propyl-N...)
Affinity DataKi:  210nMAssay Description:Displacement of [3H]spiperone from human D2long receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274262(N-[N'-Propyl-N'-[4-(2-trimethylsilylethynyl)cycloh...)
Affinity DataKi:  220nMAssay Description:Displacement of [3H]spiperone from human D2long receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM55121(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
Affinity DataKi:  240nMAssay Description:Displacement of [3H]spiperone from human D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274408(N-[4-(4-Methyltriazol-1-yl)butyl]-N-propyl-N-(4-pr...)
Affinity DataKi:  280nMAssay Description:Displacement of [3H]spiperone from human D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274354(N-[N'-Propyl-N'-[4-(2-phenylethynyl)cyclohex-3-en-...)
Affinity DataKi:  300nMAssay Description:Displacement of [3H]spiperone from human D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274262(N-[N'-Propyl-N'-[4-(2-trimethylsilylethynyl)cycloh...)
Affinity DataKi:  360nMAssay Description:Displacement of [3H]spiperone from human D2short receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM55121(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
Affinity DataKi:  360nMAssay Description:Displacement of [3H]spiperone from human D2short receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM55121(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
Affinity DataKi:  450nMAssay Description:Displacement of [3H]spiperone from human D2long receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274407(N-[4-[4-(4-Biphenyl)triazol-1-yl]butyl]-N-propyl-N...)
Affinity DataKi:  610nMAssay Description:Displacement of [3H]spiperone from human D2long receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274411(N-[(N'-(4-Cyclohexyl)-N'-propyl)aminobutyl]-4-biph...)
Affinity DataKi:  670nMAssay Description:Displacement of [3H]spiperone from human D4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274356(N-[4-[4-(4-Biphenyl)triazol-1-yl]butyl]-N-propyl-N...)
Affinity DataKi:  670nMAssay Description:Displacement of [3H]spiperone from human D2short receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274356(N-[4-[4-(4-Biphenyl)triazol-1-yl]butyl]-N-propyl-N...)
Affinity DataKi:  690nMAssay Description:Displacement of [3H]spiperone from human D2long receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274410(N-(4-Dipropylaminobutyl)-4-biphenylcarboxamide | C...)
Affinity DataKi:  950nMAssay Description:Displacement of [3H]spiperone from human D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274357(N-[4-[4-(4-Biphenyl)triazol-1-yl]butyl]-N-propyl-N...)
Affinity DataKi:  1.10E+3nMAssay Description:Displacement of [3H]spiperone from human D4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274410(N-(4-Dipropylaminobutyl)-4-biphenylcarboxamide | C...)
Affinity DataKi:  1.40E+3nMAssay Description:Displacement of [3H]spiperone from human D4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Pig)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274357(N-[4-[4-(4-Biphenyl)triazol-1-yl]butyl]-N-propyl-N...)
Affinity DataKi:  1.70E+3nMAssay Description:Displacement of [3H]SCH23390 from D1 receptor in pig striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274356(N-[4-[4-(4-Biphenyl)triazol-1-yl]butyl]-N-propyl-N...)
Affinity DataKi:  1.80E+3nMAssay Description:Displacement of [3H]spiperone from human D4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274408(N-[4-(4-Methyltriazol-1-yl)butyl]-N-propyl-N-(4-pr...)
Affinity DataKi:  2.10E+3nMAssay Description:Displacement of [3H]spiperone from human D2short receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Pig)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274355(N-[N'-(4-Ethynylcyclohex-3-en-1-yl)-N'-propyl-4-am...)
Affinity DataKi:  2.90E+3nMAssay Description:Displacement of [3H]SCH23390 from D1 receptor in pig striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274354(N-[N'-Propyl-N'-[4-(2-phenylethynyl)cyclohex-3-en-...)
Affinity DataKi:  3.10E+3nMAssay Description:Displacement of [3H]spiperone from human D4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Pig)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274262(N-[N'-Propyl-N'-[4-(2-trimethylsilylethynyl)cycloh...)
Affinity DataKi:  3.80E+3nMAssay Description:Displacement of [3H]SCH23390 from D1 receptor in pig striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
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