Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50027366
TargetD(1A) dopamine receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50274531(CHEMBL520992 | CHEMBL574558 | 6-Chloro-3-methyl-1-...)
Affinity DataKi:  1.18nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD(1A) dopamine receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50274612((+/-)-3-Methyl-6-(naphthalen-2-yl)-1-m-tolyl-2,3,4...)
Affinity DataKi:  4.88nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50274611((+/-)-3-Methyl-1,6-di-(m-tolyl)-2,3,4,5-tetrahydro...)
Affinity DataKi:  6.81nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50274530((1R)-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin...)
Affinity DataKi:  26nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50274612((+/-)-3-Methyl-6-(naphthalen-2-yl)-1-m-tolyl-2,3,4...)
Affinity DataKi:  29nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50274567((+/-)-1-phenyl-6-m-tolyl-2,3,4,5-tetrahydro-1H-ben...)
Affinity DataKi:  39nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50274612((+/-)-3-Methyl-6-(naphthalen-2-yl)-1-m-tolyl-2,3,4...)
Affinity DataKi:  43nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor expressed in cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50274570((+/-)-6-(naphthalen-2-yl)-1-phenyl-2,3,4,5-tetrahy...)
Affinity DataKi:  56nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50274611((+/-)-3-Methyl-1,6-di-(m-tolyl)-2,3,4,5-tetrahydro...)
Affinity DataKi:  121nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor expressed in cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50004923(CHEMBL542700 | 1-Phenyl-2,3,4,5-tetrahydro-1H-benz...)
Affinity DataKi:  190nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50274568((+/-)-6-(4-chlorophenyl)-1-phenyl-2,3,4,5-tetrahyd...)
Affinity DataKi:  190nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50274611((+/-)-3-Methyl-1,6-di-(m-tolyl)-2,3,4,5-tetrahydro...)
Affinity DataKi:  210nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50274532((+/-)-1,6-Diphenyl-2,3,4,5-tetrahydro-1H-benzo[d]a...)
Affinity DataKi:  346nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50274570((+/-)-6-(naphthalen-2-yl)-1-phenyl-2,3,4,5-tetrahy...)
Affinity DataKi:  375nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor expressed in cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50274569((+/-)-6-(4-fluorophenyl)-1-phenyl-2,3,4,5-tetrahyd...)
Affinity DataKi:  422nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50274567((+/-)-1-phenyl-6-m-tolyl-2,3,4,5-tetrahydro-1H-ben...)
Affinity DataKi:  736nMAssay Description:Displacement of [3H]8-OH-DPAT from rat 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50274532((+/-)-1,6-Diphenyl-2,3,4,5-tetrahydro-1H-benzo[d]a...)
Affinity DataKi:  775nMAssay Description:Displacement of [3H]8-OH-DPAT from rat 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50274570((+/-)-6-(naphthalen-2-yl)-1-phenyl-2,3,4,5-tetrahy...)
Affinity DataKi:  1.08E+3nMAssay Description:Displacement of [3H]8-OH-DPAT from rat 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50274530((1R)-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed