Compile Data Set for Download or QSAR
Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 3565
TargetNitric oxide synthase, inducible(Human)
The Scripps Research Institute

LigandPNGBDBM36395(CID21192814 | 5-Fluoro-2-thiophen-2-yl-1,2-dihydro...)
Affinity DataIC50: 10nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNitric oxide synthase, inducible(Human)
The Scripps Research Institute

LigandPNGBDBM50091817(CHEMBL302657 | 4-Methyl-6-propylpyridin-2-amine, 7...)
Affinity DataIC50: 15nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNitric oxide synthase, brain(Human)
The Scripps Research Institute

LigandPNGBDBM50091817(CHEMBL302657 | 4-Methyl-6-propylpyridin-2-amine, 7...)
Affinity DataIC50: 23nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
The Scripps Research Institute

LigandPNGBDBM36396(CD24894148 | N-[2-(4-Amino-5,8-difluoro-1,2-dihydr...)
Affinity DataIC50: 31nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNitric oxide synthase, endothelial(Human)
The Scripps Research Institute

LigandPNGBDBM50091817(CHEMBL302657 | 4-Methyl-6-propylpyridin-2-amine, 7...)
Affinity DataIC50: 34nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
The Scripps Research Institute

LigandPNGBDBM50124535(5-[(4'-amino-5',8'-difluoro-1H,1'H-spiro[piperidin...)
Affinity DataIC50: 35nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNitric oxide synthase, inducible(Human)
The Scripps Research Institute

LigandPNGBDBM36401(CID24894153 | (2S)-2-Methyl-2,3-dihydrothieno[2,3-...)
Affinity DataIC50: 40nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
The Scripps Research Institute

LigandPNGBDBM36402(CID24894154 | (3R)-3-Propyl-2,3-dihydrothieno[2,3-...)
Affinity DataIC50: 40nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
The Scripps Research Institute

LigandPNGBDBM36402(CID24894154 | (3R)-3-Propyl-2,3-dihydrothieno[2,3-...)
Affinity DataIC50: 50nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
The Scripps Research Institute

LigandPNGBDBM50148167(CHEMBL114500 | 4-(4-(4-methoxypyridin-2-ylamino)pi...)
Affinity DataIC50: 74nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNitric oxide synthase, endothelial(Human)
The Scripps Research Institute

LigandPNGBDBM36401(CID24894153 | (2S)-2-Methyl-2,3-dihydrothieno[2,3-...)
Affinity DataIC50: 80nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
The Scripps Research Institute

LigandPNGBDBM36401(CID24894153 | (2S)-2-Methyl-2,3-dihydrothieno[2,3-...)
Affinity DataIC50: 80nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
The Scripps Research Institute

LigandPNGBDBM50148164(Ethyl 4-[(4-methoxypyridin-2-yl)amino]piperidine-1...)
Affinity DataIC50: 90nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
The Scripps Research Institute

LigandPNGBDBM50091800(4-METHYLPYRIDIN-2-AMINE, 6 | 4-METHYLPYRIDIN-2-AMI...)
Affinity DataIC50: 120nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNitric oxide synthase, inducible(Human)
The Scripps Research Institute

LigandPNGBDBM36399(CID10221335 | N-[2-(6-Amino-4-methylpyridin-2-yl)e...)
Affinity DataIC50: 120nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNitric oxide synthase, inducible(Human)
The Scripps Research Institute

LigandPNGBDBM36397(CID24894149 | (4-Amino-5-fluorospiro[1H-quinazolin...)
Affinity DataIC50: 130nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNitric oxide synthase, brain(Human)
The Scripps Research Institute

LigandPNGBDBM50091800(4-METHYLPYRIDIN-2-AMINE, 6 | 4-METHYLPYRIDIN-2-AMI...)
Affinity DataIC50: 160nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
The Scripps Research Institute

LigandPNGBDBM36402(CID24894154 | (3R)-3-Propyl-2,3-dihydrothieno[2,3-...)
Affinity DataIC50: 200nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
The Scripps Research Institute

LigandPNGBDBM50091800(4-METHYLPYRIDIN-2-AMINE, 6 | 4-METHYLPYRIDIN-2-AMI...)
Affinity DataIC50: 320nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
The Scripps Research Institute

LigandPNGBDBM50148162(Ethyl 4-[(4-methylpyridin-2-yl)amino]piperidine-1-...)
Affinity DataIC50: 350nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNitric oxide synthase, inducible(Human)
The Scripps Research Institute

LigandPNGBDBM36403(CID24894155 | (3R)-3-(1,2,3,4-Tetrahydroisoquinoli...)
Affinity DataIC50: 400nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
The Scripps Research Institute

LigandPNGBDBM36400(CID24894151 | Ethyl 4-[(4-chloropyridin-2-yl)amino...)
Affinity DataIC50: 720nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
The Scripps Research Institute

LigandPNGBDBM50124535(5-[(4'-amino-5',8'-difluoro-1H,1'H-spiro[piperidin...)
Affinity DataIC50: 790nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
The Scripps Research Institute

LigandPNGBDBM36399(CID10221335 | N-[2-(6-Amino-4-methylpyridin-2-yl)e...)
Affinity DataIC50: 790nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
The Scripps Research Institute

LigandPNGBDBM36403(CID24894155 | (3R)-3-(1,2,3,4-Tetrahydroisoquinoli...)
Affinity DataIC50: 1.00E+3nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
The Scripps Research Institute

LigandPNGBDBM36395(CID21192814 | 5-Fluoro-2-thiophen-2-yl-1,2-dihydro...)
Affinity DataIC50: 1.00E+3nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
The Scripps Research Institute

LigandPNGBDBM36398(CID24894150 | 4-(4'-Amino-1'-ethyl-5'-...)
Affinity DataIC50: 1.20E+3nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
The Scripps Research Institute

LigandPNGBDBM36395(CID21192814 | 5-Fluoro-2-thiophen-2-yl-1,2-dihydro...)
Affinity DataIC50: 2.50E+3nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
The Scripps Research Institute

LigandPNGBDBM36396(CD24894148 | N-[2-(4-Amino-5,8-difluoro-1,2-dihydr...)
Affinity DataIC50: 3.10E+3nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
The Scripps Research Institute

LigandPNGBDBM36396(CD24894148 | N-[2-(4-Amino-5,8-difluoro-1,2-dihydr...)
Affinity DataIC50: 4.90E+3nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
The Scripps Research Institute

LigandPNGBDBM50148167(CHEMBL114500 | 4-(4-(4-methoxypyridin-2-ylamino)pi...)
Affinity DataIC50: 6.00E+3nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
The Scripps Research Institute

LigandPNGBDBM36399(CID10221335 | N-[2-(6-Amino-4-methylpyridin-2-yl)e...)
Affinity DataIC50: 7.40E+3nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
The Scripps Research Institute

LigandPNGBDBM36397(CID24894149 | (4-Amino-5-fluorospiro[1H-quinazolin...)
Affinity DataIC50: 7.80E+3nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
The Scripps Research Institute

LigandPNGBDBM50148162(Ethyl 4-[(4-methylpyridin-2-yl)amino]piperidine-1-...)
Affinity DataIC50: 2.00E+4nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
The Scripps Research Institute

LigandPNGBDBM50148164(Ethyl 4-[(4-methoxypyridin-2-yl)amino]piperidine-1...)
Affinity DataIC50: 3.00E+4nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
The Scripps Research Institute

LigandPNGBDBM36403(CID24894155 | (3R)-3-(1,2,3,4-Tetrahydroisoquinoli...)
Affinity DataIC50: 5.00E+4nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
The Scripps Research Institute

LigandPNGBDBM50148162(Ethyl 4-[(4-methylpyridin-2-yl)amino]piperidine-1-...)
Affinity DataIC50: 5.80E+4nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNitric oxide synthase, brain(Human)
The Scripps Research Institute

LigandPNGBDBM36400(CID24894151 | Ethyl 4-[(4-chloropyridin-2-yl)amino...)
Affinity DataIC50: 6.30E+4nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
The Scripps Research Institute

LigandPNGBDBM50148167(CHEMBL114500 | 4-(4-(4-methoxypyridin-2-ylamino)pi...)
Affinity DataIC50: 1.00E+5nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
The Scripps Research Institute

LigandPNGBDBM50148164(Ethyl 4-[(4-methoxypyridin-2-yl)amino]piperidine-1...)
Affinity DataIC50: 1.00E+5nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
The Scripps Research Institute

LigandPNGBDBM36400(CID24894151 | Ethyl 4-[(4-chloropyridin-2-yl)amino...)
Affinity DataIC50: 1.00E+5nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
The Scripps Research Institute

LigandPNGBDBM36398(CID24894150 | 4-(4'-Amino-1'-ethyl-5'-...)
Affinity DataIC50: 1.00E+5nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
The Scripps Research Institute

LigandPNGBDBM36398(CID24894150 | 4-(4'-Amino-1'-ethyl-5'-...)
Affinity DataIC50: 1.00E+5nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
The Scripps Research Institute

LigandPNGBDBM36397(CID24894149 | (4-Amino-5-fluorospiro[1H-quinazolin...)
Affinity DataIC50: 1.00E+5nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
The Scripps Research Institute

LigandPNGBDBM50124535(5-[(4'-amino-5',8'-difluoro-1H,1'H-spiro[piperidin...)
Affinity DataIC50: 1.00E+5nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2011
Entry Details Article
PubMed