Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50027433
TargetFarnesyl pyrophosphate synthase(Human)
Universita Di Ferrara

Curated by ChEMBL
LigandPNGBDBM12578(CHEMBL924 | [1-hydroxy-2-(1H-imidazol-1-yl)-1-phos...)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of human FPP synthase expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFarnesyl pyrophosphate synthase(Human)
Universita Di Ferrara

Curated by ChEMBL
LigandPNGBDBM50273714([2-(Imidazol-1-yl)ethyl]-bisphosphonic acid | CHEM...)
Affinity DataIC50: 9.03nMAssay Description:Inhibition of human FPP synthase expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
Universita Di Ferrara

Curated by ChEMBL
LigandPNGBDBM50273716([2-(Benzoimidazol-1-yl)ethyl]-bisphosphonic acid |...)
Affinity DataIC50: 16.1nMAssay Description:Inhibition of human FPP synthase expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
Universita Di Ferrara

Curated by ChEMBL
LigandPNGBDBM50273717([2-(Imidazol-2-yl-thio)ethyl]-bisphosphonic acid |...)
Affinity DataIC50: 28.1nMAssay Description:Inhibition of human FPP synthase expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
Universita Di Ferrara

Curated by ChEMBL
LigandPNGBDBM50273718([2-(Purin-9-yl)ethyl]-bisphosphonic acid | CHEMBL4...)
Affinity DataIC50: 388nMAssay Description:Inhibition of human FPP synthase expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
Universita Di Ferrara

Curated by ChEMBL
LigandPNGBDBM50273799([2-(6-Chloro-purin-9-yl)ethyl]-bisphosphonic acid ...)
Affinity DataIC50: 883nMAssay Description:Inhibition of human FPP synthase expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
Universita Di Ferrara

Curated by ChEMBL
LigandPNGBDBM50273715([2-(Pyrazol-1-yl)ethyl]-bisphosphonic acid | CHEMB...)
Affinity DataIC50: 3.07E+3nMAssay Description:Inhibition of human FPP synthase expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed