Compile Data Set for Download or QSAR
Report error Found 50 Enz. Inhib. hit(s) with all data for entry = 50027445
TargetBone morphogenetic protein 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50241177(5-{(1R)-4-cyclohexyl-1-[2-(hydroxylamino)-2-oxoeth...)
Affinity DataIC50: 9.30nMAssay Description:Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50241177(5-{(1R)-4-cyclohexyl-1-[2-(hydroxylamino)-2-oxoeth...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human procollagen C-proteinase expressed in CHO cells by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50256367((R)-2-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50: 17nMAssay Description:Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50256368((R)-2-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50: 17nMAssay Description:Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50256203((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50: 21nMAssay Description:Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50256303((R)-2-(5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan...)
Affinity DataIC50: 21nMAssay Description:Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50256306((R)-6-cyclohexyl-N-hydroxy-3-(3-(morpholine-4-carb...)
Affinity DataIC50: 25nMAssay Description:Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50256305((R)-6-cyclohexyl-N-hydroxy-3-(3-(piperidine-1-carb...)
Affinity DataIC50: 26nMAssay Description:Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216795((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50: 26nMAssay Description:Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50256150((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50: 28nMAssay Description:Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50256151((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50: 32nMAssay Description:Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50256204((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50: 33nMAssay Description:Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216798((R)-ethyl 5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohe...)
Affinity DataIC50: 36nMAssay Description:Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50256302((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50: 37nMAssay Description:Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50256096((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50256304((R)-6-cyclohexyl-N-hydroxy-3-(3-(pyrrolidine-1-car...)
Affinity DataIC50: 43nMAssay Description:Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216795((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50: 44nMAssay Description:Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50256207((R)-2-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50: 45nMAssay Description:Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50256365((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50: 54nMAssay Description:Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50256205((R)-N-benzyl-5-(6-cyclohexyl-1-(hydroxyamino)-1-ox...)
Affinity DataIC50: 57nMAssay Description:Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50256366((R)-N-benzyl-5-(6-cyclohexyl-1-(hydroxyamino)-1-ox...)
Affinity DataIC50: 65nMAssay Description:Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50256206((R)-2-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50: 73nMAssay Description:Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50097252((R)-N'-((S)-3,3-dimethyl-1-oxo-1-((R)-1-phenylethy...)
Affinity DataIC50: 135nMAssay Description:Inhibition of human MMP2 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50097259((R)-2-(3-Cyclohexyl-propyl)-N*1*-[(S)-2,2-dimethyl...)
Affinity DataIC50: 820nMAssay Description:Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50216795((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50: 900nMAssay Description:Inhibition of PDE4DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50097259((R)-2-(3-Cyclohexyl-propyl)-N*1*-[(S)-2,2-dimethyl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human MMP2 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50216795((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of PDE4BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50216795((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of PDE4AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50256149((S)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50216795((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of PDE4CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216835((R)-ethyl 5-(1-(hydroxyamino)-1-oxo-6-phenylhexan-...)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of human MMP2 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216835((R)-ethyl 5-(1-(hydroxyamino)-1-oxo-6-phenylhexan-...)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50097252((R)-N'-((S)-3,3-dimethyl-1-oxo-1-((R)-1-phenylethy...)
Affinity DataIC50: 8.77E+3nMAssay Description:Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216795((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MMP3 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216795((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of interstitial MMP1 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216795((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MMP9 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216795((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MMP14 catalytic domain by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50256151((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50: 2.17E+4nMAssay Description:Inhibition of human MMP2 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50241177(5-{(1R)-4-cyclohexyl-1-[2-(hydroxylamino)-2-oxoeth...)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of human MMP3 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50256150((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human MMP2 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50256204((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human MMP2 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50256302((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human MMP2 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50256096((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50: 5.05E+4nMAssay Description:Inhibition of human MMP2 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216795((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of human MMP2 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50256305((R)-6-cyclohexyl-N-hydroxy-3-(3-(piperidine-1-carb...)
Affinity DataIC50: 7.49E+4nMAssay Description:Inhibition of human MMP2 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216798((R)-ethyl 5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohe...)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of human MMP2 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50256366((R)-N-benzyl-5-(6-cyclohexyl-1-(hydroxyamino)-1-ox...)
Affinity DataIC50: 8.18E+4nMAssay Description:Inhibition of human MMP2 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50256303((R)-2-(5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human MMP2 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50256203((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human MMP2 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50241177(5-{(1R)-4-cyclohexyl-1-[2-(hydroxylamino)-2-oxoeth...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human MMP2 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed