Compile Data Set for Download or QSAR
Report error Found 50 Enz. Inhib. hit(s) with all data for entry = 50032227
TargetTyrosine-protein kinase TXK(Human)
Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM13216(N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyeth...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of TXKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 5(Human)
Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of MAP4K5More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase Yes(Human)
Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of YES1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase ABL1(Human)
Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of ABL1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase ABL2(Human)
Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of ABL2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 1nMAssay Description:Inhibition of SRCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase Fgr(Human)
Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of FGRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fyn(Human)
Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of FYNMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase FRK(Human)
Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of FRKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of BTKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetActivated CDC42 kinase 1(Human)
Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of TNK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase HCK(Human)
Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of HCKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase 24(Human)
Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of STK24More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEphrin type-B receptor 2(Human)
Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM13216(N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyeth...)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of EPHB2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of EPHB4More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase Blk(Mouse)
Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 7.30nMAssay Description:Inhibition of mouse BLKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Human)
Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of BMXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lyn(Human)
Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 8nMAssay Description:Inhibition of LYNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lyn(Human)
Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 8nMAssay Description:Inhibition of LYNBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase Blk(Mouse)
Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM13216(N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyeth...)
Affinity DataIC50: 8nMAssay Description:Inhibition of mouse BLKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 2(Human)
Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 8.5nMAssay Description:Inhibition of EPHB2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 2(Human)
Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 9.90nMAssay Description:Inhibition of MAP4K2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetMisshapen-like kinase 1(Human)
Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 22nMAssay Description:Inhibition of MINK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 22nMAssay Description:Inhibition of TRKAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetBDNF/NT-3 growth factors receptor(Human)
Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 27nMAssay Description:Inhibition of TRKBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase TXK(Human)
Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 40nMAssay Description:Inhibition of TXKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase 10(Human)
Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 52nMAssay Description:Inhibition of STK10More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase SYK(Human)
Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 52nMAssay Description:Inhibition of SYKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 53nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase CSK(Human)
Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 63nMAssay Description:Inhibition of CSKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM13216(N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyeth...)
Affinity DataIC50: 63nMAssay Description:Inhibition of PDGFRaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase type 1D(Human)
Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 92nMAssay Description:Inhibition of CAMK1DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM13216(N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyeth...)
Affinity DataIC50: 93nMAssay Description:Inhibition of cKITMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM13216(N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyeth...)
Affinity DataIC50: 109nMAssay Description:Inhibition of RIPK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetLIM domain kinase 1(Human)
Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM13216(N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyeth...)
Affinity DataIC50: 114nMAssay Description:Inhibition of LIMK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetProtein-tyrosine kinase 2-beta(Human)
Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 134nMAssay Description:Inhibition of PTK2BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM13216(N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyeth...)
Affinity DataIC50: 164nMAssay Description:Inhibition of cRAFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 174nMAssay Description:Inhibition of AXLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase type II subunit gamma(Human)
Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 184nMAssay Description:Inhibition of CAMK2GMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase 4(Human)
Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 191nMAssay Description:Inhibition of STK4More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase Tec(Human)
Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 282nMAssay Description:Inhibition of TECMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM13216(N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyeth...)
Affinity DataIC50: 322nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fes/Fps(Human)
Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 358nMAssay Description:Inhibition of FESMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase TBK1(Human)
Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 471nMAssay Description:Inhibition of TBK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fer(Human)
Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 490nMAssay Description:Inhibition of FERMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 538nMAssay Description:Inhibition of PTK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 574nMAssay Description:Inhibition of IRAK4More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 1.19E+3nMAssay Description:Inhibition of TIE2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of cKITMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed