Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 3041
TargetHistone deacetylase 1(Human)
Georgia Institute of Technology

LigandPNGBDBM27188(triazole-linked clarithromycin-based compound, 24d)
Affinity DataIC50: 1.90nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Georgia Institute of Technology

LigandPNGBDBM27187(triazole-linked clarithromycin-based compound, 24c)
Affinity DataIC50: 4.10nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Georgia Institute of Technology

LigandPNGBDBM27180(7-{4-[4-({[(2S,3R,4S,6R)-2-{[(2R,3S,4R,5R,8R,10R,1...)
Affinity DataIC50: 10.6nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Georgia Institute of Technology

LigandPNGBDBM27179(triazole-linked azithromycin-based compound, 16c)
Affinity DataIC50: 13.9nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Georgia Institute of Technology

LigandPNGBDBM27185(triazole-linked clarithromycin-based compound, 24a)
Affinity DataIC50: 37nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Georgia Institute of Technology

LigandPNGBDBM27186(triazole-linked clarithromycin-based compound, 24b)
Affinity DataIC50: 44.3nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Georgia Institute of Technology

LigandPNGBDBM27189(triazole-linked clarithromycin-based compound, 24e)
Affinity DataIC50: 55.6nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Georgia Institute of Technology

LigandPNGBDBM27181(triazole-linked azithromycin-based compound, 16e)
Affinity DataIC50: 58.9nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Georgia Institute of Technology

LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 65nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 1(Human)
Georgia Institute of Technology

LigandPNGBDBM27182(8-{4-[4-({[(2S,3R,4S,6R)-2-{[(2R,3S,4R,5R,8R,10R,1...)
Affinity DataIC50: 72.4nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Georgia Institute of Technology

LigandPNGBDBM27178(6-{4-[4-({[(2S,3R,4S,6R)-2-{[(2R,3S,4R,5R,8R,10R,1...)
Affinity DataIC50: 88.8nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Georgia Institute of Technology

LigandPNGBDBM27177(triazole-linked azithromycin-based compound, 16a)
Affinity DataIC50: 91.6nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Georgia Institute of Technology

LigandPNGBDBM27175(Azithromycinarylalkylhydroxamic Acid, 8)
Affinity DataIC50: 107nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Georgia Institute of Technology

LigandPNGBDBM27176(Desclasinose Azithromycinarylalkyl Hydroxamate, 10)
Affinity DataIC50: 110nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Georgia Institute of Technology

LigandPNGBDBM27190(triazole-linked clarithromycin-based compound, 24f)
Affinity DataIC50: 123nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Georgia Institute of Technology

LigandPNGBDBM27183(triazole-linked azithromycin-based compound, 16g)
Affinity DataIC50: 146nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Georgia Institute of Technology

LigandPNGBDBM27191(triazole-linked clarithromycin-based compound, 24g)
Affinity DataIC50: 170nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Georgia Institute of Technology

LigandPNGBDBM27192(triazole-linked clarithromycin-based compound, 24h)
Affinity DataIC50: 223nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Georgia Institute of Technology

LigandPNGBDBM27184(triazole-linked azithromycin-based compound, 16h)
Affinity DataIC50: 227nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2009
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Georgia Institute of Technology

LigandPNGBDBM27179(triazole-linked azithromycin-based compound, 16c)
Affinity DataIC50: 994nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2009
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Georgia Institute of Technology

LigandPNGBDBM27180(7-{4-[4-({[(2S,3R,4S,6R)-2-{[(2R,3S,4R,5R,8R,10R,1...)
Affinity DataIC50: 1.02E+3nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2009
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Georgia Institute of Technology

LigandPNGBDBM27188(triazole-linked clarithromycin-based compound, 24d)
Affinity DataIC50: 1.39E+3nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2009
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Georgia Institute of Technology

LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 1.86E+3nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 8(Human)
Georgia Institute of Technology

LigandPNGBDBM27187(triazole-linked clarithromycin-based compound, 24c)
Affinity DataIC50: 1.89E+3nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2009
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Georgia Institute of Technology

LigandPNGBDBM27176(Desclasinose Azithromycinarylalkyl Hydroxamate, 10)
Affinity DataIC50: 2.32E+3nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2009
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Georgia Institute of Technology

LigandPNGBDBM27178(6-{4-[4-({[(2S,3R,4S,6R)-2-{[(2R,3S,4R,5R,8R,10R,1...)
Affinity DataIC50: 3.74E+3nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2009
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Georgia Institute of Technology

LigandPNGBDBM27185(triazole-linked clarithromycin-based compound, 24a)
Affinity DataIC50: 3.99E+3nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2009
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Georgia Institute of Technology

LigandPNGBDBM27190(triazole-linked clarithromycin-based compound, 24f)
Affinity DataIC50: 4.42E+3nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2009
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Georgia Institute of Technology

LigandPNGBDBM27177(triazole-linked azithromycin-based compound, 16a)
Affinity DataIC50: 4.73E+3nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2009
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Georgia Institute of Technology

LigandPNGBDBM27186(triazole-linked clarithromycin-based compound, 24b)
Affinity DataIC50: 4.75E+3nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2009
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Georgia Institute of Technology

LigandPNGBDBM27189(triazole-linked clarithromycin-based compound, 24e)
Affinity DataIC50: 5.88E+3nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2009
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Georgia Institute of Technology

LigandPNGBDBM27175(Azithromycinarylalkylhydroxamic Acid, 8)
Affinity DataIC50: 6.68E+3nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2009
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Georgia Institute of Technology

LigandPNGBDBM27182(8-{4-[4-({[(2S,3R,4S,6R)-2-{[(2R,3S,4R,5R,8R,10R,1...)
Affinity DataIC50: 6.78E+3nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2009
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Georgia Institute of Technology

LigandPNGBDBM27181(triazole-linked azithromycin-based compound, 16e)
Affinity DataIC50: 7.13E+3nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2009
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Georgia Institute of Technology

LigandPNGBDBM27191(triazole-linked clarithromycin-based compound, 24g)
Affinity DataIC50: 1.06E+4nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2009
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Georgia Institute of Technology

LigandPNGBDBM27183(triazole-linked azithromycin-based compound, 16g)
Affinity DataIC50: 1.11E+4nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2009
Entry Details Article
PubMed