Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50027955
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50256750(N-(6-amino-5-chloropyridin-3-yl)-2-chloro-5-(3-(tr...)
Affinity DataIC50: 5nMAssay Description:Inhibition of CSF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50256750(N-(6-amino-5-chloropyridin-3-yl)-2-chloro-5-(3-(tr...)
Affinity DataIC50: 5nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50256750(N-(6-amino-5-chloropyridin-3-yl)-2-chloro-5-(3-(tr...)
Affinity DataIC50: 31nMAssay Description:Inhibition of PDGFRbMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50256724(N-(5-chloropyridin-3-yl)-5-(3-(2-cyanopropan-2-yl)...)
Affinity DataIC50: 400nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50256750(N-(6-amino-5-chloropyridin-3-yl)-2-chloro-5-(3-(tr...)
Affinity DataIC50: 478nMAssay Description:Inhibition of PTK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50256750(N-(6-amino-5-chloropyridin-3-yl)-2-chloro-5-(3-(tr...)
Affinity DataIC50: 672nMAssay Description:Inhibition of EphB4More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50256750(N-(6-amino-5-chloropyridin-3-yl)-2-chloro-5-(3-(tr...)
Affinity DataIC50: 700nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50256751(N-(6-amino-5-chloropyridin-3-yl)-2-methyl-5-(3-(tr...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50256679(5-(3-(2-cyanopropan-2-yl)benzamido)-2-methyl-N-(5-...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50256727(N-(6-amino-5-chloropyridin-3-yl)-5-(3-(2-cyanoprop...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50256636(5-(3-(2-cyanopropan-2-yl)benzamido)-2-methyl-N-(6-...)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50256634(5-(3-(2-cyanopropan-2-yl)benzamido)-2-methyl-N-(6-...)
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50256750(N-(6-amino-5-chloropyridin-3-yl)-2-chloro-5-(3-(tr...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50256750(N-(6-amino-5-chloropyridin-3-yl)-2-chloro-5-(3-(tr...)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of Jak2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50256750(N-(6-amino-5-chloropyridin-3-yl)-2-chloro-5-(3-(tr...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of KdrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50256750(N-(6-amino-5-chloropyridin-3-yl)-2-chloro-5-(3-(tr...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of IGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50256750(N-(6-amino-5-chloropyridin-3-yl)-2-chloro-5-(3-(tr...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50256750(N-(6-amino-5-chloropyridin-3-yl)-2-chloro-5-(3-(tr...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of PlkMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50256750(N-(6-amino-5-chloropyridin-3-yl)-2-chloro-5-(3-(tr...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 1(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50256750(N-(6-amino-5-chloropyridin-3-yl)-2-chloro-5-(3-(tr...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Pak1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50256750(N-(6-amino-5-chloropyridin-3-yl)-2-chloro-5-(3-(tr...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase CSK(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50256750(N-(6-amino-5-chloropyridin-3-yl)-2-chloro-5-(3-(tr...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CskMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50256750(N-(6-amino-5-chloropyridin-3-yl)-2-chloro-5-(3-(tr...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Jnk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50256750(N-(6-amino-5-chloropyridin-3-yl)-2-chloro-5-(3-(tr...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Cdk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed