Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 50028022
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255261(N-(2-aminophenyl)-4-((4-(6-morpholinopyridin-3-yl)...)
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255378(N-(2-aminophenyl)-4-((4-(thiophen-3-yl)pyrimidin-2...)
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255101(N-(2-aminophenyl)-4-((6-(pyridin-3-yl)pyrimidin-4-...)
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255425(N-(2-aminophenyl)-4-((4-(4-(2-morpholinoethoxy)phe...)
Affinity DataIC50: 80nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255262(N-(2-aminophenyl)-4-((4-(6-(4-methylpiperazin-1-yl...)
Affinity DataIC50: 80nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255424(N-(2-aminophenyl)-4-((4-(4-(morpholinomethyl)pheny...)
Affinity DataIC50: 90nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255917(N-(2-aminophenyl)-4-((3-(pyridin-3-yl)phenylamino)...)
Affinity DataIC50: 90nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255263(N-(2-aminophenyl)-4-((4-(6-(methylthio)pyridin-3-y...)
Affinity DataIC50: 90nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255102(N-(2-aminophenyl)-4-((6-(pyridin-3-yl)pyrazin-2-yl...)
Affinity DataIC50: 110nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255469(N-(2-aminophenyl)-4-((4-(4-(2-(dimethylamino)ethox...)
Affinity DataIC50: 120nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50234080(N-(2-aminophenyl)-4-(3-(4-(pyridin-3-yl)pyrimidin-...)
Affinity DataIC50: 130nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255470(N-(2-aminophenyl)-4-((4-(3-(2-(dimethylamino)ethox...)
Affinity DataIC50: 130nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255422(4-((4-(1H-pyrazol-5-yl)pyrimidin-2-ylamino)methyl)...)
Affinity DataIC50: 140nMAssay Description:Inhibition of HDAC2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255379(N-(2-aminophenyl)-4-((4-(thiazol-2-yl)pyrimidin-2-...)
Affinity DataIC50: 140nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255422(4-((4-(1H-pyrazol-5-yl)pyrimidin-2-ylamino)methyl)...)
Affinity DataIC50: 140nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255468(N-(2-aminophenyl)-4-((4-(3-(2-morpholinoethoxy)phe...)
Affinity DataIC50: 140nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM24624(MGCD-0103 | N-(2-aminophenyl)-4-({[4-(pyridin-3-yl...)
Affinity DataIC50: 150nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255321(N-(2-aminophenyl)-4-((4-(6-cyanopyridin-3-yl)pyrim...)
Affinity DataIC50: 160nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255260(4-((4-amino-6-(pyridin-3-yl)pyrimidin-2-ylamino)me...)
Affinity DataIC50: 170nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255099(4-((2,3'-bipyridin-6-ylamino)methyl)-N-(2-aminophe...)
Affinity DataIC50: 180nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255377(N-(2-aminophenyl)-4-((4-(pyrazin-2-yl)pyrimidin-2-...)
Affinity DataIC50: 190nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255100(N-(2-aminophenyl)-4-((2-(pyridin-3-yl)pyrimidin-4-...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255423(N-(2-aminophenyl)-4-((4-(3-(hydroxymethyl)isoxazol...)
Affinity DataIC50: 210nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255323(N-(2-aminophenyl)-4-((4-(6-(2-hydroxypropan-2-yl)p...)
Affinity DataIC50: 230nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255146(N-(2-aminophenyl)-4-((2-(methylthio)-6-(pyridin-3-...)
Affinity DataIC50: 250nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255322(N-(2-aminophenyl)-4-((4-(6-(2-(methoxymethoxy)prop...)
Affinity DataIC50: 250nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255376(N-(2-aminophenyl)-4-((4-(6-(morpholine-4-carbonyl)...)
Affinity DataIC50: 250nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM24624(MGCD-0103 | N-(2-aminophenyl)-4-({[4-(pyridin-3-yl...)
Affinity DataIC50: 290nMAssay Description:Inhibition of HDAC2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255422(4-((4-(1H-pyrazol-5-yl)pyrimidin-2-ylamino)methyl)...)
Affinity DataIC50: 320nMAssay Description:Inhibition of HDAC3More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255324(5-(2-(4-(2-aminophenylcarbamoyl)benzylamino)pyrimi...)
Affinity DataIC50: 420nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255916((E)-N-(2-aminophenyl)-3-(4-((4-(pyridin-3-yl)pyrim...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM24624(MGCD-0103 | N-(2-aminophenyl)-4-({[4-(pyridin-3-yl...)
Affinity DataIC50: 1.66E+3nMAssay Description:Inhibition of HDAC3More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255915(N-(2-aminophenyl)-4-(4-(pyridin-3-yl)pyrimidin-2-y...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM24624(MGCD-0103 | N-(2-aminophenyl)-4-({[4-(pyridin-3-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM24624(MGCD-0103 | N-(2-aminophenyl)-4-({[4-(pyridin-3-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC7More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM24624(MGCD-0103 | N-(2-aminophenyl)-4-({[4-(pyridin-3-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC5More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM24624(MGCD-0103 | N-(2-aminophenyl)-4-({[4-(pyridin-3-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC8More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255422(4-((4-(1H-pyrazol-5-yl)pyrimidin-2-ylamino)methyl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC8More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255422(4-((4-(1H-pyrazol-5-yl)pyrimidin-2-ylamino)methyl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC5More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255422(4-((4-(1H-pyrazol-5-yl)pyrimidin-2-ylamino)methyl)...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255856(2-amino-N-(4-((4-(pyridin-3-yl)pyrimidin-2-ylamino...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255857(N-(2-aminophenyl)-3-((4-(pyridin-3-yl)pyrimidin-2-...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255422(4-((4-(1H-pyrazol-5-yl)pyrimidin-2-ylamino)methyl)...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of HDAC7More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255855(N-phenyl-4-((4-(pyridin-3-yl)pyrimidin-2-ylamino)m...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed