Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 3045
LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)
Affinity DataIC50: 4nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2009
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Universite De Lyon

LigandPNGBDBM27217(GP0210 | (2R)-2-{[4-(benzylamino)-8-(propan-2-yl)p...)
Affinity DataIC50: 40nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2009
Entry Details Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Universite De Lyon

LigandPNGBDBM27217(GP0210 | (2R)-2-{[4-(benzylamino)-8-(propan-2-yl)p...)
Affinity DataIC50: 43nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2009
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Universite De Lyon

LigandPNGBDBM27218((2R)-2-({4-[(3-chlorophenyl)amino]-8-(propan-2-yl)...)
Affinity DataIC50: 60nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1 [99-307](Human)
Universite De Lyon

LigandPNGBDBM27218((2R)-2-({4-[(3-chlorophenyl)amino]-8-(propan-2-yl)...)
Affinity DataIC50: 60nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2009
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Universite De Lyon

LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)
Affinity DataIC50: 70nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1 [99-307](Human)
Universite De Lyon

LigandPNGBDBM27217(GP0210 | (2R)-2-{[4-(benzylamino)-8-(propan-2-yl)p...)
Affinity DataIC50: 70nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2009
Entry Details Article
PubMed
LigandPNGBDBM27217(GP0210 | (2R)-2-{[4-(benzylamino)-8-(propan-2-yl)p...)
Affinity DataIC50: 73nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1 [99-307](Human)
Universite De Lyon

LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)
Affinity DataIC50: 75nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2009
Entry Details Article
PubMed
LigandPNGBDBM27218((2R)-2-({4-[(3-chlorophenyl)amino]-8-(propan-2-yl)...)
Affinity DataIC50: 80nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1 [99-307](Human)
Universite De Lyon

LigandPNGBDBM27220((2S)-2-{[4-(benzylamino)-8-(propan-2-yl)pyrazolo[1...)
Affinity DataIC50: 130nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2009
Entry Details Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Universite De Lyon

LigandPNGBDBM27219((2R)-2-{[4-(benzylamino)-7-(propan-2-yl)imidazo[1,...)
Affinity DataIC50: 200nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2009
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Universite De Lyon

LigandPNGBDBM7533(2,6,9-Trisubstituted purine deriv. 28 | (2R)-2-[[6...)
Affinity DataIC50: 220nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2009
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Universite De Lyon

LigandPNGBDBM27219((2R)-2-{[4-(benzylamino)-7-(propan-2-yl)imidazo[1,...)
Affinity DataIC50: 220nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2009
Entry Details Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Universite De Lyon

LigandPNGBDBM7533(2,6,9-Trisubstituted purine deriv. 28 | (2R)-2-[[6...)
Affinity DataIC50: 230nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1 [99-307](Human)
Universite De Lyon

LigandPNGBDBM7533(2,6,9-Trisubstituted purine deriv. 28 | (2R)-2-[[6...)
Affinity DataIC50: 270nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1 [99-307](Human)
Universite De Lyon

LigandPNGBDBM27219((2R)-2-{[4-(benzylamino)-7-(propan-2-yl)imidazo[1,...)
Affinity DataIC50: 320nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2009
Entry Details Article
PubMed
LigandPNGBDBM7533(2,6,9-Trisubstituted purine deriv. 28 | (2R)-2-[[6...)
Affinity DataIC50: 330nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2009
Entry Details Article
PubMed
LigandPNGBDBM27219((2R)-2-{[4-(benzylamino)-7-(propan-2-yl)imidazo[1,...)
Affinity DataIC50: 400nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2009
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Universite De Lyon

LigandPNGBDBM27217(GP0210 | (2R)-2-{[4-(benzylamino)-8-(propan-2-yl)p...)
Affinity DataIC50: 500nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2009
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Universite De Lyon

LigandPNGBDBM27219((2R)-2-{[4-(benzylamino)-7-(propan-2-yl)imidazo[1,...)
Affinity DataIC50: 600nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2009
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Universite De Lyon

LigandPNGBDBM7533(2,6,9-Trisubstituted purine deriv. 28 | (2R)-2-[[6...)
Affinity DataIC50: 800nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2009
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Universite De Lyon

LigandPNGBDBM27218((2R)-2-({4-[(3-chlorophenyl)amino]-8-(propan-2-yl)...)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2009
Entry Details Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Universite De Lyon

LigandPNGBDBM27218((2R)-2-({4-[(3-chlorophenyl)amino]-8-(propan-2-yl)...)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2009
Entry Details Article
PubMed