Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 5670
TargetReplicase polyprotein 1ab(SARS-CoV)
National Yang-Ming University

LigandPNGBDBM92520(TG-0204998)
Affinity DataKi:  38nM ΔG°:  -42.4kJ/molepH: 6.5 T: 2°CAssay Description:Peptidomimetic inhibitors against CVB3 3Cpro and SARS-CoV 3CLpro. The inhibition constant of SARS 3CLpro was analyzed with reverse-phase HPLC using a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
National Yang-Ming University

LigandPNGBDBM11233(benzyl N-[(1S,2S)-2-(tert-butoxy)-1-{[(1S)-2-cyclo...)
Affinity DataKi:  54nM ΔG°:  -41.5kJ/molepH: 6.5 T: 2°CAssay Description:Peptidomimetic inhibitors against CVB3 3Cpro and SARS-CoV 3CLpro. The inhibition constant of SARS 3CLpro was analyzed with reverse-phase HPLC using a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
National Yang-Ming University

LigandPNGBDBM11232(ethyl (2E,4S)-4-[(2S)-2-[(2S,3S)-2-{[(benzyloxy)ca...)
Affinity DataKi:  58nM ΔG°:  -41.3kJ/molepH: 6.5 T: 2°CAssay Description:Peptidomimetic inhibitors against CVB3 3Cpro and SARS-CoV 3CLpro. The inhibition constant of SARS 3CLpro was analyzed with reverse-phase HPLC using a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
National Yang-Ming University

LigandPNGBDBM92521(TG-0205486)
Affinity DataKi:  99nM ΔG°:  -40.0kJ/molepH: 6.5 T: 2°CAssay Description:Peptidomimetic inhibitors against CVB3 3Cpro and SARS-CoV 3CLpro. The inhibition constant of SARS 3CLpro was analyzed with reverse-phase HPLC using a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetGenome polyprotein(Coxsackievirus B3 (strain Nancy))
National Yang-Ming University

LigandPNGBDBM92521(TG-0205486)
Affinity DataKi:  400nM ΔG°:  -36.5kJ/molepH: 6.5 T: 2°CAssay Description:Peptidomimetic inhibitors against CVB3 3Cpro and SARS-CoV 3CLpro. The inhibition constant of SARS 3CLpro was analyzed with reverse-phase HPLC using a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetGenome polyprotein(Coxsackievirus B3 (strain Nancy))
National Yang-Ming University

LigandPNGBDBM92520(TG-0204998)
Affinity DataKi:  800nM ΔG°:  -34.8kJ/molepH: 6.5 T: 2°CAssay Description:Peptidomimetic inhibitors against CVB3 3Cpro and SARS-CoV 3CLpro. The inhibition constant of SARS 3CLpro was analyzed with reverse-phase HPLC using a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetGenome polyprotein(Coxsackievirus B3 (strain Nancy))
National Yang-Ming University

LigandPNGBDBM11232(ethyl (2E,4S)-4-[(2S)-2-[(2S,3S)-2-{[(benzyloxy)ca...)
Affinity DataKi:  1.50E+3nM ΔG°:  -33.2kJ/molepH: 6.5 T: 2°CAssay Description:Peptidomimetic inhibitors against CVB3 3Cpro and SARS-CoV 3CLpro. The inhibition constant of SARS 3CLpro was analyzed with reverse-phase HPLC using a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetGenome polyprotein(Coxsackievirus B3 (strain Nancy))
National Yang-Ming University

LigandPNGBDBM11233(benzyl N-[(1S,2S)-2-(tert-butoxy)-1-{[(1S)-2-cyclo...)
Affinity DataKi:  2.50E+3nM ΔG°:  -32.0kJ/molepH: 6.5 T: 2°CAssay Description:Peptidomimetic inhibitors against CVB3 3Cpro and SARS-CoV 3CLpro. The inhibition constant of SARS 3CLpro was analyzed with reverse-phase HPLC using a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed