Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50030234
TargetSodium-dependent noradrenaline transporter(Human)
Sirtris Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50228363(N-(2-(3-(piperazin-1-ylmethyl)imidazo[2,1-b]thiazo...)
Affinity DataIC50: 2.47E+3nMAssay Description:Inhibition of norepinephrine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Sirtris Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50228363(N-(2-(3-(piperazin-1-ylmethyl)imidazo[2,1-b]thiazo...)
Affinity DataIC50: 2.83E+3nMAssay Description:Inhibition of adrenergic alpha2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Sirtris Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50228363(N-(2-(3-(piperazin-1-ylmethyl)imidazo[2,1-b]thiazo...)
Affinity DataIC50: 6.28E+3nMAssay Description:Inhibition of muscarinic M2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Sirtris Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50228363(N-(2-(3-(piperazin-1-ylmethyl)imidazo[2,1-b]thiazo...)
Affinity DataIC50: 8.02E+3nMAssay Description:Inhibition of muscarinic M1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sirtris Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50228363(N-(2-(3-(piperazin-1-ylmethyl)imidazo[2,1-b]thiazo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ERG by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Sirtris Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50228364(3,4,5-trimethoxy-N-(2-(3-(piperazin-1-ylmethyl)imi...)
Affinity DataKd:  1.62E+4nMAssay Description:Binding affinity to SIRT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed