Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50030223
TargetNitric oxide synthase, inducible(Human)
Universita G. D'Annunzio

Curated by ChEMBL
LigandPNGBDBM50292744(1-(Benzylamino)ethaniminium bromide | CHEMBL462334)
Affinity DataIC50: 200nMAssay Description:Inhibition of iNOS in LPS treated human THP1 cell homogenate assessed as conversion of L-[2,3-3H]arginine to L-[2,3-3H]citrulline pre-incubated 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Universita G. D'Annunzio

Curated by ChEMBL
LigandPNGBDBM50292746((+/-)-N-(1-Phenylpropyl)ethanimidamide hydrobromid...)
Affinity DataIC50: 250nMAssay Description:Inhibition of iNOS in LPS treated human THP1 cell homogenate assessed as conversion of L-[2,3-3H]arginine to L-[2,3-3H]citrulline pre-incubated 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Universita G. D'Annunzio

Curated by ChEMBL
LigandPNGBDBM50292749(1-[(1-Propionylpiperidin-4-yl)amino]ethaniminium b...)
Affinity DataIC50: 250nMAssay Description:Inhibition of iNOS in LPS treated human THP1 cell homogenate assessed as conversion of L-[2,3-3H]arginine to L-[2,3-3H]citrulline pre-incubated 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Universita G. D'Annunzio

Curated by ChEMBL
LigandPNGBDBM50226527(N-[3-(aminomethyl)benzyl]ethanimidamide | N-(3-Ami...)
Affinity DataIC50: 330nMAssay Description:Inhibition of iNOS in LPS treated human THP1 cell homogenate assessed as conversion of L-[2,3-3H]arginine to L-[2,3-3H]citrulline pre-incubated 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Universita G. D'Annunzio

Curated by ChEMBL
LigandPNGBDBM50292747(1-[(3-{[(Pyridin-4-ylmethyl)amino]methyl}benzyl)am...)
Affinity DataIC50: 350nMAssay Description:Inhibition of iNOS in LPS treated human THP1 cell homogenate assessed as conversion of L-[2,3-3H]arginine to L-[2,3-3H]citrulline pre-incubated 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Universita G. D'Annunzio

Curated by ChEMBL
LigandPNGBDBM50292745(1-[(1-Phenylethyl)amino]ethaniminium bromide | CHE...)
Affinity DataIC50: 450nMAssay Description:Inhibition of iNOS in LPS treated human THP1 cell homogenate assessed as conversion of L-[2,3-3H]arginine to L-[2,3-3H]citrulline pre-incubated 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Universita G. D'Annunzio

Curated by ChEMBL
LigandPNGBDBM50292748(1-{[3-({[(4-Methylphenyl)sulfonyl]amino}methyl)ben...)
Affinity DataIC50: 500nMAssay Description:Inhibition of iNOS in LPS treated human THP1 cell homogenate assessed as conversion of L-[2,3-3H]arginine to L-[2,3-3H]citrulline pre-incubated 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Universita G. D'Annunzio

Curated by ChEMBL
LigandPNGBDBM50292747(1-[(3-{[(Pyridin-4-ylmethyl)amino]methyl}benzyl)am...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of eNOS in LPS treated human THP1 cell homogenate assessed as conversion of L-[2,3-3H]arginine to L-[2,3-3H]citrulline pre-incubated 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Universita G. D'Annunzio

Curated by ChEMBL
LigandPNGBDBM50292746((+/-)-N-(1-Phenylpropyl)ethanimidamide hydrobromid...)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of eNOS in LPS treated human THP1 cell homogenate assessed as conversion of L-[2,3-3H]arginine to L-[2,3-3H]citrulline pre-incubated 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Universita G. D'Annunzio

Curated by ChEMBL
LigandPNGBDBM50292749(1-[(1-Propionylpiperidin-4-yl)amino]ethaniminium b...)
Affinity DataIC50: 9.00E+4nMAssay Description:Inhibition of eNOS in LPS treated human THP1 cell homogenate assessed as conversion of L-[2,3-3H]arginine to L-[2,3-3H]citrulline pre-incubated 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Universita G. D'Annunzio

Curated by ChEMBL
LigandPNGBDBM50292745(1-[(1-Phenylethyl)amino]ethaniminium bromide | CHE...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of eNOS in LPS treated human THP1 cell homogenate assessed as conversion of L-[2,3-3H]arginine to L-[2,3-3H]citrulline pre-incubated 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Universita G. D'Annunzio

Curated by ChEMBL
LigandPNGBDBM50292748(1-{[3-({[(4-Methylphenyl)sulfonyl]amino}methyl)ben...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of eNOS in LPS treated human THP1 cell homogenate assessed as conversion of L-[2,3-3H]arginine to L-[2,3-3H]citrulline pre-incubated 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Universita G. D'Annunzio

Curated by ChEMBL
LigandPNGBDBM50292744(1-(Benzylamino)ethaniminium bromide | CHEMBL462334)
Affinity DataIC50: 3.50E+5nMAssay Description:Inhibition of eNOS in LPS treated human THP1 cell homogenate assessed as conversion of L-[2,3-3H]arginine to L-[2,3-3H]citrulline pre-incubated 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Universita G. D'Annunzio

Curated by ChEMBL
LigandPNGBDBM50226527(N-[3-(aminomethyl)benzyl]ethanimidamide | N-(3-Ami...)
Affinity DataIC50: 1.10E+6nMAssay Description:Inhibition of eNOS in LPS treated human THP1 cell homogenate assessed as conversion of L-[2,3-3H]arginine to L-[2,3-3H]citrulline pre-incubated 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed