Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50030231
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50292902((2R,3R)-3-(4-(aminomethyl)-4-phenylpiperidin-1-yl)...)
Affinity DataKd:  3nMAssay Description:Displacement of [3H]vesamicol from human vesicular acetylcholine transporter expressed in rat PC12 cells by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50039613(trans-3-(4-phenylpiperidin-1-yl)-1,2,3,4-tetrahydr...)
Affinity DataKi:  0.0550nMAssay Description:Displacement of [3H]vesamicol from human vesicular acetylcholine transporter expressed in rat PC12 cells by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50046952(CHEMBL1956464 | CHEMBL129530 | trans-1-(4-fluorobe...)
Affinity DataKi:  0.220nMAssay Description:Displacement of [3H]vesamicol from human vesicular acetylcholine transporter expressed in rat PC12 cells by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50292908((+/-)-trans-2-Hydroxy-3-(4-(4-bromobenzoyl)piperid...)
Affinity DataKi:  0.25nMAssay Description:Displacement of [3H]vesamicol from human vesicular acetylcholine transporter expressed in rat PC12 cells by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50292905((2R,3R)-5-(3-iodoallyloxy)-3-(4-phenylpiperidin-1-...)
Affinity DataKi:  0.450nMAssay Description:Displacement of [3H]vesamicol from human vesicular acetylcholine transporter expressed in rat PC12 cells by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50292910((+/-)-trans-2-Hydroxy-3-(4-(4-nitrobenzoyl)piperid...)
Affinity DataKi:  0.480nMAssay Description:Displacement of [3H]vesamicol from human vesicular acetylcholine transporter expressed in rat PC12 cells by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50292906((2R,3R)-5-(3-fluoropropoxy)-3-(4-phenylpiperidin-1...)
Affinity DataKi:  0.770nMAssay Description:Displacement of [3H]vesamicol from human vesicular acetylcholine transporter expressed in rat PC12 cells by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50292911((+/-)-trans-2-Hydroxy-3-(4-(4-aminobenzoyl)piperid...)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]vesamicol from human vesicular acetylcholine transporter expressed in rat PC12 cells by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50018094((1R,2R)-2-(4-Phenyl-piperidin-1-yl)-cyclohexanol |...)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]vesamicol from human vesicular acetylcholine transporter expressed in rat PC12 cells by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50292907((+/-)-trans-2-Hydroxy-3-(4-(4-fluorobenzoyl)piperi...)
Affinity DataKi:  4.10nMAssay Description:Displacement of [3H]vesamicol from human vesicular acetylcholine transporter expressed in rat PC12 cells by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50292909(CHEMBL1186644 | CHEMBL473546 | (+/-)-trans-2-Hydro...)
Affinity DataKi:  4.30nMAssay Description:Displacement of [3H]vesamicol from human vesicular acetylcholine transporter expressed in rat PC12 cells by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50292903((1R,2R,4S)-4-(4-fluorobenzyloxy)-2-(4-phenylpiperi...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]vesamicol from human vesicular acetylcholine transporter expressed in rat PC12 cells by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Washington University

Curated by ChEMBL
LigandPNGBDBM50292904((1R,2R,5R)-5-(4-fluorobenzyloxy)-2-(4-phenylpiperi...)
Affinity DataKi:  21nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in guinea pig brain membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Washington University

Curated by ChEMBL
LigandPNGBDBM50046952(CHEMBL1956464 | CHEMBL129530 | trans-1-(4-fluorobe...)
Affinity DataKi:  22nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in guinea pig brain membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Washington University

Curated by ChEMBL
LigandPNGBDBM50018094((1R,2R)-2-(4-Phenyl-piperidin-1-yl)-cyclohexanol |...)
Affinity DataKi:  26nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in guinea pig brain membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Washington University

Curated by ChEMBL
LigandPNGBDBM50292903((1R,2R,4S)-4-(4-fluorobenzyloxy)-2-(4-phenylpiperi...)
Affinity DataKi:  31nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in guinea pig brain membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Washington University

Curated by ChEMBL
LigandPNGBDBM50292907((+/-)-trans-2-Hydroxy-3-(4-(4-fluorobenzoyl)piperi...)
Affinity DataKi:  186nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in guinea pig brain membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Washington University

Curated by ChEMBL
LigandPNGBDBM50292907((+/-)-trans-2-Hydroxy-3-(4-(4-fluorobenzoyl)piperi...)
Affinity DataKi:  186nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in guinea pig brain membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Washington University

Curated by ChEMBL
LigandPNGBDBM50292909(CHEMBL1186644 | CHEMBL473546 | (+/-)-trans-2-Hydro...)
Affinity DataKi:  220nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in guinea pig brain membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Washington University

Curated by ChEMBL
LigandPNGBDBM50292908((+/-)-trans-2-Hydroxy-3-(4-(4-bromobenzoyl)piperid...)
Affinity DataKi:  298nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in guinea pig brain membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50292904((1R,2R,5R)-5-(4-fluorobenzyloxy)-2-(4-phenylpiperi...)
Affinity DataKi:  330nMAssay Description:Displacement of [3H]vesamicol from human vesicular acetylcholine transporter expressed in rat PC12 cells by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed