Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50030232
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM79214(3-(dibutylamino)-1-[1,3-dichloro-6-(trifluoromethy...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human cloned ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM586429(Amodiaquin | USRE49340, Rank 6 | BDBM50041457)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human cloned ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM22985(Aralen | Chlorochin | CHLOROQUINE PHOSPHATE | Chlo...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human cloned ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C8(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM586429(Amodiaquin | USRE49340, Rank 6 | BDBM50041457)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human recombinant CYP2C8More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50134936(N-tert-Butyl isoquine | 2-(tert-Butylamino-methyl)...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human recombinant CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50134934(5-(7-Chloro-quinolin-4-ylamino)-2-ethylaminomethyl...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of human recombinant CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50134931(isoquine | 5-(7-chloroquinolin-4-ylamino)-2-((diet...)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of human cloned ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM586429(Amodiaquin | USRE49340, Rank 6 | BDBM50041457)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of human recombinant CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50056190(bidesethylamodiaquine | desethylamodiaquine | Mono...)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of human recombinant CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50134931(isoquine | 5-(7-chloroquinolin-4-ylamino)-2-((diet...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human recombinant CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50134936(N-tert-Butyl isoquine | 2-(tert-Butylamino-methyl)...)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of human cloned ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50134934(5-(7-Chloro-quinolin-4-ylamino)-2-ethylaminomethyl...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of human recombinant CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50056190(bidesethylamodiaquine | desethylamodiaquine | Mono...)
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of human cloned ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C8(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50134931(isoquine | 5-(7-chloroquinolin-4-ylamino)-2-((diet...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human recombinant CYP2C8More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM586429(Amodiaquin | USRE49340, Rank 6 | BDBM50041457)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human recombinant CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C8(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50056190(bidesethylamodiaquine | desethylamodiaquine | Mono...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant CYP2C8More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C8(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50134934(5-(7-Chloro-quinolin-4-ylamino)-2-ethylaminomethyl...)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of human recombinant CYP2C8More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C8(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50134936(N-tert-Butyl isoquine | 2-(tert-Butylamino-methyl)...)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of human recombinant CYP2C8More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50134931(isoquine | 5-(7-chloroquinolin-4-ylamino)-2-((diet...)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of human recombinant CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50134936(N-tert-Butyl isoquine | 2-(tert-Butylamino-methyl)...)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of human recombinant CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50056190(bidesethylamodiaquine | desethylamodiaquine | Mono...)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of human recombinant CYP3A4 using N-N,diethyl-formamide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM586429(Amodiaquin | USRE49340, Rank 6 | BDBM50041457)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of human recombinant CYP3A4 using N-N,diethyl-formamide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50056190(bidesethylamodiaquine | desethylamodiaquine | Mono...)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of human recombinant CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50134936(N-tert-Butyl isoquine | 2-(tert-Butylamino-methyl)...)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of human recombinant CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50134931(isoquine | 5-(7-chloroquinolin-4-ylamino)-2-((diet...)
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of human recombinant CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50056190(bidesethylamodiaquine | desethylamodiaquine | Mono...)
Affinity DataIC50: 5.40E+4nMAssay Description:Inhibition of human recombinant CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50056190(bidesethylamodiaquine | desethylamodiaquine | Mono...)
Affinity DataIC50: 5.80E+4nMAssay Description:Inhibition of human recombinant CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM586429(Amodiaquin | USRE49340, Rank 6 | BDBM50041457)
Affinity DataIC50: 6.20E+4nMAssay Description:Inhibition of human recombinant CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50134934(5-(7-Chloro-quinolin-4-ylamino)-2-ethylaminomethyl...)
Affinity DataIC50: 6.20E+4nMAssay Description:Inhibition of human recombinant CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50134931(isoquine | 5-(7-chloroquinolin-4-ylamino)-2-((diet...)
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibition of human recombinant CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50134934(5-(7-Chloro-quinolin-4-ylamino)-2-ethylaminomethyl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50056190(bidesethylamodiaquine | desethylamodiaquine | Mono...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant CYP3A4 using phenyl-piperazinyl-methyl-benzyl-resofurin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50134936(N-tert-Butyl isoquine | 2-(tert-Butylamino-methyl)...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant CYP3A4 using phenyl-piperazinyl-methyl-benzyl-resofurin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50134931(isoquine | 5-(7-chloroquinolin-4-ylamino)-2-((diet...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant CYP3A4 using phenyl-piperazinyl-methyl-benzyl-resofurin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM586429(Amodiaquin | USRE49340, Rank 6 | BDBM50041457)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant CYP3A4 using phenyl-piperazinyl-methyl-benzyl-resofurin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50134934(5-(7-Chloro-quinolin-4-ylamino)-2-ethylaminomethyl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant CYP3A4 using N-N,diethyl-formamide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed