Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 50028406
TargetGonadotropin-releasing hormone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256836(7-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...)
Affinity DataIC50: 1.80nMAssay Description:Displacement of [D-Trp6]-GnRH from human recombinant GnRH receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256834(7-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...)
Affinity DataIC50: 3.5nMAssay Description:Displacement of [D-Trp6]-GnRH from human recombinant GnRH receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244211(6-{4-[2-(4-tert-Butyl-phenyl)-1H-benzoimidazol-4-y...)
Affinity DataIC50: 4.90nMAssay Description:Displacement of [D-Trp6]-GnRH from human recombinant GnRH receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256835(7-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...)
Affinity DataIC50: 5.60nMAssay Description:Displacement of [D-Trp6]-GnRH from human recombinant GnRH receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256834(7-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...)
Affinity DataIC50: 7.40nMAssay Description:Antagonist activity at human GnRH receptor assessed as inhibition of [D-Trp6]-GnRH-stimulated [3H]IP reductionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244211(6-{4-[2-(4-tert-Butyl-phenyl)-1H-benzoimidazol-4-y...)
Affinity DataIC50: 9.40nMAssay Description:Antagonist activity at human GnRH receptor assessed as inhibition of [D-Trp6]-GnRH-stimulated [3H]IP reductionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256836(7-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...)
Affinity DataIC50: 9.70nMAssay Description:Antagonist activity at human GnRH receptor assessed as inhibition of [D-Trp6]-GnRH-stimulated [3H]IP reductionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256882(6-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...)
Affinity DataIC50: 12nMAssay Description:Displacement of [D-Trp6]-GnRH from human recombinant GnRH receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256835(7-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...)
Affinity DataIC50: 14nMAssay Description:Antagonist activity at human GnRH receptor assessed as inhibition of [D-Trp6]-GnRH-stimulated [3H]IP reductionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256881(6-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...)
Affinity DataIC50: 16nMAssay Description:Antagonist activity at human GnRH receptor assessed as inhibition of [D-Trp6]-GnRH-stimulated [3H]IP reductionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256881(6-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...)
Affinity DataIC50: 16nMAssay Description:Displacement of [D-Trp6]-GnRH from human recombinant GnRH receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256834(7-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...)
Affinity DataIC50: 17nMAssay Description:Displacement of [D-Trp6]-GnRH from rat recombinant GnRH receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256883(6-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...)
Affinity DataIC50: 21nMAssay Description:Displacement of [D-Trp6]-GnRH from human recombinant GnRH receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256884(7-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...)
Affinity DataIC50: 24nMAssay Description:Displacement of [D-Trp6]-GnRH from human recombinant GnRH receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244211(6-{4-[2-(4-tert-Butyl-phenyl)-1H-benzoimidazol-4-y...)
Affinity DataIC50: 25nMAssay Description:Antagonist activity at rat recombinant GnRH receptor assessed as inhibition of [D-Trp6]-GnRH-stimulated LH release from rat pituitary cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256939(5-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...)
Affinity DataIC50: 26nMAssay Description:Displacement of [D-Trp6]-GnRH from human recombinant GnRH receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256882(6-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...)
Affinity DataIC50: 28nMAssay Description:Antagonist activity at human GnRH receptor assessed as inhibition of [D-Trp6]-GnRH-stimulated [3H]IP reductionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256836(7-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...)
Affinity DataIC50: 33nMAssay Description:Displacement of [D-Trp6]-GnRH from rat recombinant GnRH receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244211(6-{4-[2-(4-tert-Butyl-phenyl)-1H-benzoimidazol-4-y...)
Affinity DataIC50: 40nMAssay Description:Displacement of [D-Trp6]-GnRH from rat recombinant GnRH receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256834(7-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...)
Affinity DataIC50: 44nMAssay Description:Antagonist activity at rat recombinant GnRH receptor assessed as inhibition of [D-Trp6]-GnRH-stimulated LH release from rat pituitary cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256835(7-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...)
Affinity DataIC50: 47nMAssay Description:Displacement of [D-Trp6]-GnRH from rat recombinant GnRH receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256883(6-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...)
Affinity DataIC50: 64nMAssay Description:Antagonist activity at human GnRH receptor assessed as inhibition of [D-Trp6]-GnRH-stimulated [3H]IP reductionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256835(7-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...)
Affinity DataIC50: 69nMAssay Description:Antagonist activity at rat recombinant GnRH receptor assessed as inhibition of [D-Trp6]-GnRH-stimulated LH release from rat pituitary cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256882(6-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...)
Affinity DataIC50: 71nMAssay Description:Displacement of [D-Trp6]-GnRH from rat recombinant GnRH receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256881(6-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...)
Affinity DataIC50: 87nMAssay Description:Displacement of [D-Trp6]-GnRH from rat recombinant GnRH receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256881(6-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...)
Affinity DataIC50: 120nMAssay Description:Antagonist activity at rat recombinant GnRH receptor assessed as inhibition of [D-Trp6]-GnRH-stimulated LH release from rat pituitary cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256884(7-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...)
Affinity DataIC50: 140nMAssay Description:Antagonist activity at human GnRH receptor assessed as inhibition of [D-Trp6]-GnRH-stimulated [3H]IP reductionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256836(7-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...)
Affinity DataIC50: 240nMAssay Description:Antagonist activity at rat recombinant GnRH receptor assessed as inhibition of [D-Trp6]-GnRH-stimulated LH release from rat pituitary cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256882(6-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...)
Affinity DataIC50: 320nMAssay Description:Antagonist activity at rat recombinant GnRH receptor assessed as inhibition of [D-Trp6]-GnRH-stimulated LH release from rat pituitary cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256939(5-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...)
Affinity DataIC50: 400nMAssay Description:Antagonist activity at human GnRH receptor assessed as inhibition of [D-Trp6]-GnRH-stimulated [3H]IP reductionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256884(7-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...)
Affinity DataIC50: 540nMAssay Description:Antagonist activity at rat recombinant GnRH receptor assessed as inhibition of [D-Trp6]-GnRH-stimulated LH release from rat pituitary cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256883(6-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...)
Affinity DataIC50: 830nMAssay Description:Antagonist activity at rat recombinant GnRH receptor assessed as inhibition of [D-Trp6]-GnRH-stimulated LH release from rat pituitary cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256939(5-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...)
Affinity DataIC50: 5.90E+3nMAssay Description:Antagonist activity at rat recombinant GnRH receptor assessed as inhibition of [D-Trp6]-GnRH-stimulated LH release from rat pituitary cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256882(6-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...)
Affinity DataKi:  330nMAssay Description:Inhibition of human neurokinin NK2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256882(6-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...)
Affinity DataKi:  850nMAssay Description:Inhibition of human histamine H2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed