Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50028459
TargetHistamine H3 receptor(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50278495(4-chloro-1-(4-(3-(piperidin-1-yl)propoxy)benzyl)pi...)
Affinity DataKi:  0.0680nMAssay Description:Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in HEL293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50278350(CHEMBL513193 | CHEMBL2203701 | 4-fluoro-1-(4-(3-(p...)
Affinity DataKi:  0.0940nMAssay Description:Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in HEL293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50278449(4-bromo-1-(4-(3-(piperidin-1-yl)propoxy)benzyl)pip...)
Affinity DataKi:  0.200nMAssay Description:Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in HEL293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50278448(4,4-difluoro-1-(4-(3-(piperidin-1-yl)propoxy)benzy...)
Affinity DataKi:  0.240nMAssay Description:Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in HEL293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50278445(4-fluoro-1-(4-(3-(pyrrolidin-1-yl)propoxy)benzyl)p...)
Affinity DataKi:  0.260nMAssay Description:Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in HEL293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50278400((S)-1-(3-(4-((3-fluoropyrrolidin-1-yl)methyl)pheno...)
Affinity DataKi:  0.280nMAssay Description:Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in HEL293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50278444((R)-1-(3-(4-((3-fluoropyrrolidin-1-yl)methyl)pheno...)
Affinity DataKi:  0.280nMAssay Description:Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in HEL293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50278446((R)-3-fluoro-1-(4-(3-(pyrrolidin-1-yl)propoxy)benz...)
Affinity DataKi:  0.310nMAssay Description:Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in HEL293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50159110(1-(3-(4-(piperidin-1-ylmethyl)phenoxy)propyl)piper...)
Affinity DataKi:  0.580nMAssay Description:Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in HEL293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50278496(1-(4-(3-(piperidin-1-yl)propoxy)benzyl)piperidin-4...)
Affinity DataKi:  0.840nMAssay Description:Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in HEL293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50278447(4-fluoro-1-(3-(4-(pyrrolidin-1-ylmethyl)phenoxy)pr...)
Affinity DataKi:  0.990nMAssay Description:Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in HEL293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50247053(Tiprolisant | 1-(3-(3-(4-chlorophenyl)propoxy)prop...)
Affinity DataKi:  2.70nMAssay Description:Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in HEL293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50126888(CHEMBL193978 | CHEMBL416053 | 1-[4-(4-Piperidin-1-...)
Affinity DataKi:  2.80nMAssay Description:Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in HEL293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50133003(UCL-2138 | CHEMBL129257 | 4-(3-Piperidin-1-yl-prop...)
Affinity DataKi:  11nMAssay Description:Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in HEL293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50278398(1-(3-(4-(fluoromethyl)phenoxy)propyl)piperidine | ...)
Affinity DataKi:  17.3nMAssay Description:Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in HEL293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50278399(1-(3-(4-(2-fluoroethyl)phenoxy)propyl)piperidine |...)
Affinity DataKi:  43nMAssay Description:Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in HEL293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50278397(4-(3-(4,4-difluoropiperidin-1-yl)propoxy)benzonitr...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in HEL293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed