Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 3196
TargetNitric oxide synthase, brain(Rat)
University of California Irvine

LigandPNGBDBM29234(CHEMBL481815 | aminopyridine-pyrrolidine, 6 | US90...)
Affinity DataKi:  85nM ΔG°:  -41.0kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
University of California Irvine

LigandPNGBDBM21961(JMC522060 Compound 3 | (2S,4R)-4-[(2S)-2-amino-5-(...)
Affinity DataKi:  100nM ΔG°:  -40.6kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
University of California Irvine

LigandPNGBDBM21960(JMC522060 Compound 2 | CHEMBL227937 | 3-[(4S)-4-am...)
Affinity DataKi:  150nM ΔG°:  -39.6kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
University of California Irvine

LigandPNGBDBM29235(aminopyridine-pyrrolidine, 7)
Affinity DataKi:  250nM ΔG°:  -38.3kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
University of California Irvine

LigandPNGBDBM22030(CHEMBL481413 | CHEMBL1204421 | L-N(OMEGA)-NITROARG...)
Affinity DataKi:  300nM ΔG°:  -37.9kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
University of California Irvine

LigandPNGBDBM29233(CHEMBL508014 | aminopyridine-pyrrolidine, 5)
Affinity DataKi:  388nM ΔG°:  -37.2kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain [D597N,M336V](Rat)
University of California Irvine

LigandPNGBDBM29234(CHEMBL481815 | aminopyridine-pyrrolidine, 6 | US90...)
Affinity DataKi:  1.20E+3nM ΔG°:  -34.4kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain [D597N,M336V](Rat)
University of California Irvine

LigandPNGBDBM29235(aminopyridine-pyrrolidine, 7)
Affinity DataKi:  6.10E+3nM ΔG°:  -30.3kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
University of California Irvine

LigandPNGBDBM29232(3-({(3S,4S)-4-[(6-aminopyridin-2-yl)methyl]pyrroli...)
Affinity DataKi:  9.40E+3nM ΔG°:  -29.2kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain [D597N,M336V](Rat)
University of California Irvine

LigandPNGBDBM29233(CHEMBL508014 | aminopyridine-pyrrolidine, 5)
Affinity DataKi:  3.67E+4nM ΔG°:  -25.7kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain [D597N,M336V](Rat)
University of California Irvine

LigandPNGBDBM29232(3-({(3S,4S)-4-[(6-aminopyridin-2-yl)methyl]pyrroli...)
Affinity DataKi:  4.92E+4nM ΔG°:  -25.0kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
University of California Irvine

LigandPNGBDBM21960(JMC522060 Compound 2 | CHEMBL227937 | 3-[(4S)-4-am...)
Affinity DataKi:  8.00E+4nM ΔG°:  -23.8kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
University of California Irvine

LigandPNGBDBM29234(CHEMBL481815 | aminopyridine-pyrrolidine, 6 | US90...)
Affinity DataKi:  8.52E+4nM ΔG°:  -23.6kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
University of California Irvine

LigandPNGBDBM29235(aminopyridine-pyrrolidine, 7)
Affinity DataKi:  9.52E+4nM ΔG°:  -23.3kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
University of California Irvine

LigandPNGBDBM22030(CHEMBL481413 | CHEMBL1204421 | L-N(OMEGA)-NITROARG...)
Affinity DataKi:  1.07E+5nM ΔG°:  -23.0kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
University of California Irvine

LigandPNGBDBM21961(JMC522060 Compound 3 | (2S,4R)-4-[(2S)-2-amino-5-(...)
Affinity DataKi:  1.10E+5nM ΔG°:  -23.0kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
University of California Irvine

LigandPNGBDBM29232(3-({(3S,4S)-4-[(6-aminopyridin-2-yl)methyl]pyrroli...)
Affinity DataKi:  3.67E+5nM ΔG°:  -19.9kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
University of California Irvine

LigandPNGBDBM29233(CHEMBL508014 | aminopyridine-pyrrolidine, 5)
Affinity DataKi:  4.17E+5nM ΔG°:  -19.6kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed