Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 3571
TargetProto-oncogene tyrosine-protein kinase Src(Chicken)
Chemical Genomics Centre of The Max Planck Society

LigandPNGBDBM50115216(CHEMBL87580 | 1-[2-(3-Amino-phenyl)-5-tert-butyl-2...)
Affinity DataAssay Description:Tyrosine kinase inhibition assay using wild type cSrc measured by a fluorescence-labeled approach.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2011
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Chicken)
Chemical Genomics Centre of The Max Planck Society

LigandPNGBDBM50303586(1-(3-tert-Butyl-1-(3-nitrophenyl)-1H-pyrazol-5-yl)...)
Affinity DataAssay Description:Tyrosine kinase inhibition assay using wild type cSrc measured by a fluorescence-labeled approach.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Chemical Genomics Centre of The Max Planck Society

LigandPNGBDBM31824(1-(1-(3-Aminophenyl)-3-tert-butyl-1H-pyrazol-5-yl)...)
Affinity DataKd:  55nMAssay Description:Serine/threonine kinase inhibition assay using MAP p38 alpha fluorescence-labeled approach.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Chemical Genomics Centre of The Max Planck Society

LigandPNGBDBM50115216(CHEMBL87580 | 1-[2-(3-Amino-phenyl)-5-tert-butyl-2...)
Affinity DataKd:  197nMAssay Description:Serine/threonine kinase inhibition assay using MAP p38 alpha fluorescence-labeled approach.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Chemical Genomics Centre of The Max Planck Society

LigandPNGBDBM31825(1-(1-(3-Aminophenyl)-3-tert-butyl-1H-pyrazol-5-yl)...)
Affinity DataKd:  12nMAssay Description:Serine/threonine kinase inhibition assay using MAP p38 alpha fluorescence-labeled approach.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Chemical Genomics Centre of The Max Planck Society

LigandPNGBDBM50303586(1-(3-tert-Butyl-1-(3-nitrophenyl)-1H-pyrazol-5-yl)...)
Affinity DataKd:  8nMAssay Description:Serine/threonine kinase inhibition assay using MAP p38 alpha fluorescence-labeled approach.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Chemical Genomics Centre of The Max Planck Society

LigandPNGBDBM13216(N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyeth...)
Affinity DataKd:  495nMAssay Description:Serine/threonine kinase inhibition assay using MAP p38 alpha fluorescence-labeled approach.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProto-oncogene tyrosine-protein kinase Src(Chicken)
Chemical Genomics Centre of The Max Planck Society

LigandPNGBDBM13216(N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyeth...)
Affinity DataIC50: 0.400nM Kd:  11nMAssay Description:Tyrosine kinase inhibition assay using wild type cSrc measured by a fluorescence-labeled approach.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProto-oncogene tyrosine-protein kinase Src(Chicken)
Chemical Genomics Centre of The Max Planck Society

LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 6.30nM Kd:  8nMAssay Description:Tyrosine kinase inhibition assay using wild type cSrc measured by a fluorescence-labeled approach.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2011
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Chicken)
Chemical Genomics Centre of The Max Planck Society

LigandPNGBDBM31824(1-(1-(3-Aminophenyl)-3-tert-butyl-1H-pyrazol-5-yl)...)
Affinity DataIC50: 3.21E+4nMAssay Description:Tyrosine kinase inhibition assay using wild type cSrc measured by a fluorescence-labeled approach.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2011
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Chicken)
Chemical Genomics Centre of The Max Planck Society

LigandPNGBDBM31825(1-(1-(3-Aminophenyl)-3-tert-butyl-1H-pyrazol-5-yl)...)
Affinity DataIC50: 6.41E+4nMAssay Description:Tyrosine kinase inhibition assay using wild type cSrc measured by a fluorescence-labeled approach.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2011
Entry Details Article
PubMed