Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50028715
TargetBeta-secretase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258280(4-(2-(2-methoxy-5-nitrophenyl)-1-(4-methoxyphenyl)...)
Affinity DataIC50: 470nMpH: 6.5Assay Description:Inhibition of BACE1 at pH 6.5More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258849(4-(2-(2-methoxy-5-nitrophenyl)-1-(4-methoxyphenyl)...)
Affinity DataIC50: 1.10E+3nMpH: 4.5Assay Description:Inhibition of BACE1 at pH 4.5More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258280(4-(2-(2-methoxy-5-nitrophenyl)-1-(4-methoxyphenyl)...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of BACE1 by sAPP_NF cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258279(4-(1-(3-fluoro-4-methoxyphenyl)-2-(2-methoxy-5-nit...)
Affinity DataIC50: 3.20E+3nMpH: 6.4Assay Description:Inhibition of BACE1 at pH 6.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258278(4-(2-(2-methoxy-5-nitrophenyl)-1-(4-methoxyphenyl)...)
Affinity DataIC50: 3.40E+3nMpH: 6.5Assay Description:Inhibition of BACE1 at pH 6.5More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258278(4-(2-(2-methoxy-5-nitrophenyl)-1-(4-methoxyphenyl)...)
Affinity DataIC50: 5.70E+3nMpH: 4.5Assay Description:Inhibition of BACE1 at pH 4.5More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258847(4-(1-(4-methoxyphenyl)cyclopentyl)thiazol-2-amine ...)
Affinity DataIC50: 2.50E+4nMpH: 4.5Assay Description:Inhibition of BACE1 at pH 4.5More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258848(4-(1-(4-methoxyphenyl)-2-phenylethyl)thiazol-2-ami...)
Affinity DataIC50: 3.20E+4nMpH: 4.5Assay Description:Inhibition of BACE1 at pH 4.5More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258846(4-(1-(4-chlorophenyl)cyclopentyl)thiazol-2-amine |...)
Affinity DataIC50: 3.80E+4nMpH: 4.5Assay Description:Inhibition of BACE1 at pH 4.5More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258845(4-(1-phenylcyclopentyl)thiazol-2-amine | CHEMBL511...)
Affinity DataIC50: 2.17E+5nMpH: 4.5Assay Description:Inhibition of BACE1 at pH 4.5More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258849(4-(2-(2-methoxy-5-nitrophenyl)-1-(4-methoxyphenyl)...)
Affinity DataIC50: 2.20E+7nMAssay Description:Inhibition of BACE1 by sAPP_NF cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed