Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50033469
TargetHypoxia-inducible factor 1-alpha(Human)
Gakushuin University

Curated by ChEMBL
LigandPNGBDBM50345992(3-{[4-(3-Phenylureido)phenylamino]methyl}-benzoic ...)
Affinity DataIC50: 7.21E+3nMAssay Description:Inhibition of hypoxia-induced HIF1alpha transcriptional activity in HEK293 cells incubated for 16 hrs by hypoxia response element-driven luciferase r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Gakushuin University

Curated by ChEMBL
LigandPNGBDBM50345996(1-[4-(2,3-Dimethoxy-benzylamino)phenyl]-3-phenylur...)
Affinity DataIC50: 8.62E+3nMAssay Description:Inhibition of hypoxia-induced HIF1alpha transcriptional activity in HEK293 cells incubated for 16 hrs by hypoxia response element-driven luciferase r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Gakushuin University

Curated by ChEMBL
LigandPNGBDBM50095469([5-(1-Benzyl-1H-indazol-3-yl)-furan-2-yl]-methanol...)
Affinity DataIC50: 9.21E+3nMAssay Description:Inhibition of hypoxia-induced HIF1alpha transcriptional activity in HEK293 cells incubated for 16 hrs by hypoxia response element-driven luciferase r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Gakushuin University

Curated by ChEMBL
LigandPNGBDBM50345999(5-{[4-(3-Phenyl-ureido)-phenylamino]-methyl}-isoph...)
Affinity DataIC50: 1.51E+4nMAssay Description:Inhibition of hypoxia-induced HIF1alpha transcriptional activity in HEK293 cells incubated for 16 hrs by hypoxia response element-driven luciferase r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Gakushuin University

Curated by ChEMBL
LigandPNGBDBM50345985(1-[4-(2-Methoxy-benzylamino)phenyl]-3-phenylurea |...)
Affinity DataIC50: 1.74E+4nMAssay Description:Inhibition of hypoxia-induced HIF1alpha transcriptional activity in HEK293 cells incubated for 16 hrs by hypoxia response element-driven luciferase r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Gakushuin University

Curated by ChEMBL
LigandPNGBDBM50345995(1-[4-(3,5-Dimethoxy-benzylamino)phenyl]-3-phenylur...)
Affinity DataIC50: 1.87E+4nMAssay Description:Inhibition of hypoxia-induced HIF1alpha transcriptional activity in HEK293 cells incubated for 16 hrs by hypoxia response element-driven luciferase r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Gakushuin University

Curated by ChEMBL
LigandPNGBDBM50345998(4-Methoxy-3-{[4-(3-phenyl-ureido)-phenylamino]-met...)
Affinity DataIC50: 2.21E+4nMAssay Description:Inhibition of hypoxia-induced HIF1alpha transcriptional activity in HEK293 cells incubated for 16 hrs by hypoxia response element-driven luciferase r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Gakushuin University

Curated by ChEMBL
LigandPNGBDBM50345987(1-[4-(4-Methoxy-benzylamino)phenyl]-3-phenylurea |...)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of hypoxia-induced HIF1alpha transcriptional activity in HEK293 cells incubated for 16 hrs by hypoxia response element-driven luciferase r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Gakushuin University

Curated by ChEMBL
LigandPNGBDBM50345997(1-[4-(2,5-Dimethoxy-benzylamino)phenyl]-3-phenylur...)
Affinity DataIC50: 2.96E+4nMAssay Description:Inhibition of hypoxia-induced HIF1alpha transcriptional activity in HEK293 cells incubated for 16 hrs by hypoxia response element-driven luciferase r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Gakushuin University

Curated by ChEMBL
LigandPNGBDBM50345991(2-{[4-(3-Phenylureido)phenylamino]methyl}-benzoic ...)
Affinity DataIC50: 3.25E+4nMAssay Description:Inhibition of hypoxia-induced HIF1alpha transcriptional activity in HEK293 cells incubated for 16 hrs by hypoxia response element-driven luciferase r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Gakushuin University

Curated by ChEMBL
LigandPNGBDBM50345982(1-[4-(2-Hydroxy-benzylamino)phenyl]-3-phenylurea |...)
Affinity DataIC50: 3.27E+4nMAssay Description:Inhibition of hypoxia-induced HIF1alpha transcriptional activity in HEK293 cells incubated for 16 hrs by hypoxia response element-driven luciferase r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Gakushuin University

Curated by ChEMBL
LigandPNGBDBM50345984(1-[4-(4-Hydroxy-benzylamino)phenyl]-3-phenylurea |...)
Affinity DataIC50: 3.55E+4nMAssay Description:Inhibition of hypoxia-induced HIF1alpha transcriptional activity in HEK293 cells incubated for 16 hrs by hypoxia response element-driven luciferase r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Gakushuin University

Curated by ChEMBL
LigandPNGBDBM50345994(1-[4-(2,6-Dimethoxy-benzylamino)phenyl]-3-phenylur...)
Affinity DataIC50: 3.91E+4nMAssay Description:Inhibition of hypoxia-induced HIF1alpha transcriptional activity in HEK293 cells incubated for 16 hrs by hypoxia response element-driven luciferase r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Gakushuin University

Curated by ChEMBL
LigandPNGBDBM50345989(3-{[4-(3-Phenylureido)phenylamino]methyl}-benzoic ...)
Affinity DataIC50: 4.16E+4nMAssay Description:Inhibition of hypoxia-induced HIF1alpha transcriptional activity in HEK293 cells incubated for 16 hrs by hypoxia response element-driven luciferase r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Gakushuin University

Curated by ChEMBL
LigandPNGBDBM50345988(2-{[4-(3-Phenylureido)phenylamino]methyl}-benzoic ...)
Affinity DataIC50: 5.17E+4nMAssay Description:Inhibition of hypoxia-induced HIF1alpha transcriptional activity in HEK293 cells incubated for 16 hrs by hypoxia response element-driven luciferase r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Gakushuin University

Curated by ChEMBL
LigandPNGBDBM50345986(1-[4-(3-Methoxy-benzylamino)phenyl]-3-phenylurea |...)
Affinity DataIC50: 5.21E+4nMAssay Description:Inhibition of hypoxia-induced HIF1alpha transcriptional activity in HEK293 cells incubated for 16 hrs by hypoxia response element-driven luciferase r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Gakushuin University

Curated by ChEMBL
LigandPNGBDBM50345983(1-[4-(3-Hydroxy-benzylamino)phenyl]-3-phenylurea |...)
Affinity DataIC50: 6.99E+4nMAssay Description:Inhibition of hypoxia-induced HIF1alpha transcriptional activity in HEK293 cells incubated for 16 hrs by hypoxia response element-driven luciferase r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Gakushuin University

Curated by ChEMBL
LigandPNGBDBM50345993(4-{[4-(3-Phenylureido)phenylamino]methyl}-benzoic ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of hypoxia-induced HIF1alpha transcriptional activity in HEK293 cells incubated for 16 hrs by hypoxia response element-driven luciferase r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Gakushuin University

Curated by ChEMBL
LigandPNGBDBM50345990(4-{[4-(3-Phenylureido)phenylamino]methyl}-benzoic ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of hypoxia-induced HIF1alpha transcriptional activity in HEK293 cells incubated for 16 hrs by hypoxia response element-driven luciferase r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed