Compile Data Set for Download or QSAR
Report error Found 121 Enz. Inhib. hit(s) with all data for entry = 50030290
TargetKinesin-like protein KIF11(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293756(KSP Inhibitor, 4a | CHEMBL561696 | 2-(4-(methylthi...)
Affinity DataIC50: 520nMAssay Description:Inhibition of human kinesin spindle protein by endpoint assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293755(2-(3-fluoro-4-methoxyphenylamino)-1-(2-(trifluorom...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human kinesin spindle protein by endpoint assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293761(2-(4-(methylthio)phenylamino)-1-(2-(trifluoromethy...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human kinesin spindle protein by endpoint assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293752(1-(benzo[b]thiophen-3-ylmethyl)-2-(4-sulfamoylphen...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human kinesin spindle protein by endpoint assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293762(methyl 2-(4-sulfamoylphenylamino)-1-(2-(trifluorom...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human kinesin spindle protein by endpoint assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293760(2-(3-fluoro-4-methoxyphenylamino)-1-(2-(trifluorom...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human kinesin spindle protein by endpoint assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293769(N-(2-methoxyphenyl)-2-(4-sulfamoylphenylamino)-1-(...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human kinesin spindle protein by endpoint assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293754(2-(4-methoxyphenylamino)-1-(2-(trifluoromethyl)ben...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human kinesin spindle protein by endpoint assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293754(2-(4-methoxyphenylamino)-1-(2-(trifluoromethyl)ben...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of CYP2C9 preincubated with compoundMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293753(KSP Inhibitor, 4b | CHEMBL565195 | 2-(4-(methylsul...)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of human kinesin spindle protein by endpoint assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293749(1-(2,3-dimethoxybenzyl)-2-(4-sulfamoylphenylamino)...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human kinesin spindle protein by endpoint assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293765(2-(4-methoxyphenylamino)-N-methyl-1-(2-(trifluorom...)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of human kinesin spindle protein by endpoint assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293770(N-(2-methoxyphenyl)-2-(4-methoxyphenylamino)-1-(2-...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human kinesin spindle protein by endpoint assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293758(2-(4-(methylsulfonyl)phenylamino)-1-(2-(trifluorom...)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of human kinesin spindle protein by endpoint assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293756(KSP Inhibitor, 4a | CHEMBL561696 | 2-(4-(methylthi...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of CYP2C9 preincubated with compoundMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293744(KSP Inhibitor, 4e | CHEMBL563643 | 2-(4-sulfamoylp...)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of human kinesin spindle protein by endpoint assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293779(6-fluoro-2-(4-sulfamoylphenylamino)-1-(2-(trifluor...)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of human kinesin spindle protein by endpoint assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293753(KSP Inhibitor, 4b | CHEMBL565195 | 2-(4-(methylsul...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of CYP2C9 preincubated with compoundMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293754(2-(4-methoxyphenylamino)-1-(2-(trifluoromethyl)ben...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of CYP2C9 coincubated with compoundMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293766(N-methyl-2-(4-sulfamoylphenylamino)-1-(2-(trifluor...)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of human kinesin spindle protein by endpoint assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293763(methyl 2-(4-methoxyphenylamino)-1-(2-(trifluoromet...)
Affinity DataIC50: 1.34E+4nMAssay Description:Inhibition of human kinesin spindle protein by endpoint assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293756(KSP Inhibitor, 4a | CHEMBL561696 | 2-(4-(methylthi...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of CYP2C9 coincubated with compoundMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293756(KSP Inhibitor, 4a | CHEMBL561696 | 2-(4-(methylthi...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of CYP2D6 preincubated with compoundMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293753(KSP Inhibitor, 4b | CHEMBL565195 | 2-(4-(methylsul...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of CYP2D6 preincubated with compoundMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293754(2-(4-methoxyphenylamino)-1-(2-(trifluoromethyl)ben...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of CYP2D6 preincubated with compoundMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293753(KSP Inhibitor, 4b | CHEMBL565195 | 2-(4-(methylsul...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of CYP2C9 coincubated with compoundMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293754(2-(4-methoxyphenylamino)-1-(2-(trifluoromethyl)ben...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of CYP3A4 preincubated with compoundMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293767(N,N-dimethyl-2-(4-sulfamoylphenylamino)-1-(2-(trif...)
Affinity DataIC50: 1.63E+4nMAssay Description:Inhibition of human kinesin spindle protein by endpoint assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293751(1-((5-chlorobenzo[b]thiophen-3-yl)methyl)-2-(4-sul...)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of human kinesin spindle protein by endpoint assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293745(2-(4-sulfamoylphenylamino)-1-(1-(2-(trifluoromethy...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human kinesin spindle protein by endpoint assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293774(2-(4-(methylsulfonyl)benzylamino)-1-(2-(trifluorom...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human kinesin spindle protein by endpoint assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293775(2-(4-sulfamoylbenzylamino)-1-(2-(trifluoromethyl)b...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human kinesin spindle protein by endpoint assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293748(1-(2-methoxybenzyl)-2-(4-sulfamoylphenylamino)-1H-...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human kinesin spindle protein by endpoint assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293746(1-(1-phenylcyclopropyl)-2-(4-sulfamoylphenylamino)...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human kinesin spindle protein by endpoint assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293747(1-(pyridin-2-ylmethyl)-2-(4-sulfamoylphenylamino)-...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human kinesin spindle protein by endpoint assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293750(1-(benzo[d]thiazol-2-ylmethyl)-2-(4-sulfamoylpheny...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human kinesin spindle protein by endpoint assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293753(KSP Inhibitor, 4b | CHEMBL565195 | 2-(4-(methylsul...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP3A4 preincubated with compoundMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293757(2-(4-sulfamoylphenylamino)-1-(2-(trifluoromethyl)b...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human kinesin spindle protein by endpoint assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293759(CHEMBL563846 | KSP Inhibitor, 4f | 2-(4-methoxyphe...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human kinesin spindle protein by endpoint assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293777(2-(4-sulfamoylphenylamino)-1-(2-(trifluoromethyl)b...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human kinesin spindle protein by endpoint assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293778(5-fluoro-2-(4-sulfamoylphenylamino)-1-(2-(trifluor...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human kinesin spindle protein by endpoint assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293768(4-(5-(pyrrolidine-1-carbonyl)-1-(2-(trifluoromethy...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human kinesin spindle protein by endpoint assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293781(2-(4-(methylthio)benzyl)-1-(2-(trifluoromethyl)ben...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human kinesin spindle protein by endpoint assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293780(2-(4-methoxybenzyl)-1-(2-(trifluoromethyl)benzyl)-...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human kinesin spindle protein by endpoint assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293772(2-(4-methylbenzylamino)-1-(2-(trifluoromethyl)benz...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human kinesin spindle protein by endpoint assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293773(2-(4-methoxybenzylamino)-1-(2-(trifluoromethyl)ben...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human kinesin spindle protein by endpoint assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293771(2-(3-aminopyrrolidin-1-yl)-1-(2-(trifluoromethyl)b...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human kinesin spindle protein by endpoint assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293754(2-(4-methoxyphenylamino)-1-(2-(trifluoromethyl)ben...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP3A4 coincubated with compoundMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293756(KSP Inhibitor, 4a | CHEMBL561696 | 2-(4-(methylthi...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP3A4 coincubated with compoundMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293753(KSP Inhibitor, 4b | CHEMBL565195 | 2-(4-(methylsul...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP3A4 coincubated with compoundMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
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