Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50030428
TargetNeuropeptide Y receptor type 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296002(isopropyl 3-chloro-5-(1-(6-(2-(5-ethyl-4-methylthi...)
Affinity DataIC50: 1.40nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y1 receptor expressed in CHO cells assessed as inhibition of [35S]GTPgammaS binding by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296002(isopropyl 3-chloro-5-(1-(6-(2-(5-ethyl-4-methylthi...)
Affinity DataIC50: 36nMAssay Description:Displacement of [35S]MK499 from human ERG channel in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295987(N-ethyl-6-(2-(5-ethyl-4-methyloxazol-2-yl)ethyl)-4...)
Affinity DataIC50: 400nMAssay Description:Displacement of [35S]MK499 from human ERG channel in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295989(6-(2-(5-ethyl-4-methyloxazol-2-yl)ethyl)-4-morphol...)
Affinity DataIC50: 480nMAssay Description:Displacement of [35S]MK499 from human ERG channel in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295990(6-(2-(5-ethyl-4-methyloxazol-2-yl)ethyl)-N-isoprop...)
Affinity DataIC50: 540nMAssay Description:Displacement of [35S]MK499 from human ERG channel in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295988(6-(2-(5-ethyl-4-methyloxazol-2-yl)ethyl)-N-methyl-...)
Affinity DataIC50: 830nMAssay Description:Displacement of [35S]MK499 from human ERG channel in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295991(6-(2-(5-ethyl-4-methyloxazol-2-yl)ethyl)-N-(2-meth...)
Affinity DataIC50: 900nMAssay Description:Displacement of [35S]MK499 from human ERG channel in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295994(ethyl 2-(6-(2-(5-ethyl-4-methyloxazol-2-yl)ethyl)-...)
Affinity DataIC50: 910nMAssay Description:Displacement of [35S]MK499 from human ERG channel in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295996(6-(2-(5-ethyl-4-methyloxazol-2-yl)ethyl)-4-morphol...)
Affinity DataIC50: 1.60E+3nMAssay Description:Displacement of [35S]MK499 from human ERG channel in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295993(3-(6-(2-(5-ethyl-4-methyloxazol-2-yl)ethyl)-4-morp...)
Affinity DataIC50: 1.60E+3nMAssay Description:Displacement of [35S]MK499 from human ERG channel in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295996(6-(2-(5-ethyl-4-methyloxazol-2-yl)ethyl)-4-morphol...)
Affinity DataIC50: 4.30E+3nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y1 receptor expressed in CHO cells assessed as inhibition of [35S]GTPgammaS binding by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295992(2-(6-(2-(5-ethyl-4-methyloxazol-2-yl)ethyl)-4-morp...)
Affinity DataIC50: 4.30E+3nMAssay Description:Displacement of [35S]MK499 from human ERG channel in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295995(N-(6-(2-(5-ethyl-4-methyloxazol-2-yl)ethyl)-4-morp...)
Affinity DataIC50: 7.00E+3nMAssay Description:Displacement of [35S]MK499 from human ERG channel in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295997(2-(6-((5-ethyl-4-methyloxazol-2-ylthio)methyl)-4-m...)
Affinity DataIC50: 8.30E+3nMAssay Description:Displacement of [35S]MK499 from human ERG channel in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295989(6-(2-(5-ethyl-4-methyloxazol-2-yl)ethyl)-4-morphol...)
Affinity DataIC50: 9.00E+3nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y1 receptor expressed in CHO cells assessed as inhibition of [35S]GTPgammaS binding by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296001(2-(6-((4,5-dimethylthiazol-2-ylthio)methyl)-4-morp...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [35S]MK499 from human ERG channel in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296000(2-(4-morpholino-6-((1,4,5-trimethyl-1H-imidazol-2-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [35S]MK499 from human ERG channel in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295998(2-(6-((4,5-dimethyloxazol-2-ylthio)methyl)-4-morph...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [35S]MK499 from human ERG channel in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295991(6-(2-(5-ethyl-4-methyloxazol-2-yl)ethyl)-N-(2-meth...)
Affinity DataIC50: 1.30E+4nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y1 receptor expressed in CHO cells assessed as inhibition of [35S]GTPgammaS binding by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296001(2-(6-((4,5-dimethylthiazol-2-ylthio)methyl)-4-morp...)
Affinity DataIC50: 1.50E+4nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y1 receptor expressed in CHO cells assessed as inhibition of [35S]GTPgammaS binding by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295994(ethyl 2-(6-(2-(5-ethyl-4-methyloxazol-2-yl)ethyl)-...)
Affinity DataIC50: 1.50E+4nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y1 receptor expressed in CHO cells assessed as inhibition of [35S]GTPgammaS binding by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295987(N-ethyl-6-(2-(5-ethyl-4-methyloxazol-2-yl)ethyl)-4...)
Affinity DataIC50: 1.60E+4nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y1 receptor expressed in CHO cells assessed as inhibition of [35S]GTPgammaS binding by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295997(2-(6-((5-ethyl-4-methyloxazol-2-ylthio)methyl)-4-m...)
Affinity DataIC50: 2.10E+4nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y1 receptor expressed in CHO cells assessed as inhibition of [35S]GTPgammaS binding by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295992(2-(6-(2-(5-ethyl-4-methyloxazol-2-yl)ethyl)-4-morp...)
Affinity DataIC50: 2.10E+4nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y1 receptor expressed in CHO cells assessed as inhibition of [35S]GTPgammaS binding by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295993(3-(6-(2-(5-ethyl-4-methyloxazol-2-yl)ethyl)-4-morp...)
Affinity DataIC50: 2.20E+4nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y1 receptor expressed in CHO cells assessed as inhibition of [35S]GTPgammaS binding by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295990(6-(2-(5-ethyl-4-methyloxazol-2-yl)ethyl)-N-isoprop...)
Affinity DataIC50: 2.50E+4nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y1 receptor expressed in CHO cells assessed as inhibition of [35S]GTPgammaS binding by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295988(6-(2-(5-ethyl-4-methyloxazol-2-yl)ethyl)-N-methyl-...)
Affinity DataIC50: 3.20E+4nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y1 receptor expressed in CHO cells assessed as inhibition of [35S]GTPgammaS binding by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296000(2-(4-morpholino-6-((1,4,5-trimethyl-1H-imidazol-2-...)
Affinity DataIC50: 3.80E+4nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y1 receptor expressed in CHO cells assessed as inhibition of [35S]GTPgammaS binding by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295998(2-(6-((4,5-dimethyloxazol-2-ylthio)methyl)-4-morph...)
Affinity DataIC50: 7.00E+4nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y1 receptor expressed in CHO cells assessed as inhibition of [35S]GTPgammaS binding by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295995(N-(6-(2-(5-ethyl-4-methyloxazol-2-yl)ethyl)-4-morp...)
Affinity DataIC50: 3.20E+5nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y1 receptor expressed in CHO cells assessed as inhibition of [35S]GTPgammaS binding by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295999(2-(6-((4,5-dimethyloxazol-2-yloxy)methyl)-4-morpho...)
Affinity DataIC50: 1.00E+6nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y1 receptor expressed in CHO cells assessed as inhibition of [35S]GTPgammaS binding by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed