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Found
147
Enz. Inhib. hit(s) with all data for entry = 50030580
Target
RAC-alpha serine/threonine-protein kinase
(Human)
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM15131
(5-{5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]pyridi...)
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Affinity Data
IC50: 0.160nM
Assay Description:
Inhibition of Akt
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
PC cid
PC sid
Similars
In Depth
Date in BDB:
8/29/2010
Entry Details
Article
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PubMed
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Target
RAC-alpha serine/threonine-protein kinase
(Human)
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM50298443
(5-(5-((S)-2-amino-3-(1H-indol-3-yl)propoxy)pyridin...)
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Affinity Data
IC50: 0.170nM
Assay Description:
Inhibition of Akt
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
8/29/2010
Entry Details
Article
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PubMed
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Target
RAC-alpha serine/threonine-protein kinase
(Human)
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM16532
(pyrazolopyridine analog, 9g | (2S)-1-(1H-indol-3-y...)
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Affinity Data
IC50: 0.340nM
Assay Description:
Inhibition of Akt
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
8/29/2010
Entry Details
Article
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PubMed
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Target
RAC-alpha serine/threonine-protein kinase
(Human)
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM16534
((3Z)-5-{5-[(2S)-2-amino-3-phenylpropoxy]pyridin-3-...)
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Affinity Data
IC50: 0.600nM
Assay Description:
Inhibition of Akt
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
8/29/2010
Entry Details
Article
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PubMed
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Target
RAC-alpha serine/threonine-protein kinase
(Human)
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM50298445
(5-(5-((S)-2-amino-3-(1H-indol-3-yl)propoxy)pyridin...)
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Affinity Data
IC50: 0.700nM
Assay Description:
Inhibition of Akt
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
8/29/2010
Entry Details
Article
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PubMed
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Target
RAC-alpha serine/threonine-protein kinase
(Human)
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM50298451
((S)-1-(6-ethyl-5-(isoquinolin-6-yl)pyridin-3-yloxy...)
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Affinity Data
IC50: 0.800nM
Assay Description:
Inhibition of Akt
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
8/29/2010
Entry Details
Article
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PubMed
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Target
RAC-alpha serine/threonine-protein kinase
(Human)
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM50298444
(5-(5-((S)-2-amino-3-(1H-indol-3-yl)propoxy)pyridin...)
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Affinity Data
IC50: 0.900nM
Assay Description:
Inhibition of Akt
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
8/29/2010
Entry Details
Article
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PubMed
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Target
RAC-alpha serine/threonine-protein kinase
(Human)
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM16784
(5-{5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]pyridi...)
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Affinity Data
IC50: 1nM
Assay Description:
Inhibition of Akt
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
8/29/2010
Entry Details
Article
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PubMed
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Target
RAC-alpha serine/threonine-protein kinase
(Human)
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM50298457
((S)-1-(5-(3-ethyl-1H-indazol-5-yl)pyridin-3-yloxy)...)
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Affinity Data
IC50: 1.15nM
Assay Description:
Inhibition of Akt
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
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Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
8/29/2010
Entry Details
Article
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PubMed
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Target
RAC-alpha serine/threonine-protein kinase
(Human)
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM50298464
((S)-1-(5-(3-(1H-pyrrol-2-yl)-1H-indazol-5-yl)pyrid...)
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Affinity Data
IC50: 1.20nM
Assay Description:
Inhibition of Akt
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
8/29/2010
Entry Details
Article
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PubMed
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Target
RAC-alpha serine/threonine-protein kinase
(Human)
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM50298461
((S)-1-(1H-indol-3-yl)-3-(5-(3-(thiophen-2-yl)-1H-i...)
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Affinity Data
IC50: 1.30nM
Assay Description:
Inhibition of Akt
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
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Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
8/29/2010
Entry Details
Article
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PubMed
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Target
RAC-alpha serine/threonine-protein kinase
(Human)
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM50298433
(5-(5-((S)-2-amino-3-phenylpropoxy)pyridin-3-yl)-3-...)
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Affinity Data
IC50: 1.40nM
Assay Description:
Inhibition of Akt
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
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Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
8/29/2010
Entry Details
Article
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PubMed
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Target
RAC-alpha serine/threonine-protein kinase
(Human)
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM16957
(6-{5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]-2-(fu...)
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Affinity Data
IC50: 1.5nM
Assay Description:
Inhibition of Akt
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
8/29/2010
Entry Details
Article
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PubMed
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Target
RAC-alpha serine/threonine-protein kinase
(Human)
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM50298438
(5-(5-((S)-2-amino-3-(1H-indol-3-yl)propoxy)pyridin...)
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Affinity Data
IC50: 1.5nM
Assay Description:
Inhibition of Akt
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
8/29/2010
Entry Details
Article
Copy BDB DOI
PubMed
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Target
RAC-alpha serine/threonine-protein kinase
(Human)
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM16783
(5-{5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]pyridi...)
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Affinity Data
IC50: 1.5nM
Assay Description:
Inhibition of Akt
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
8/29/2010
Entry Details
Article
Copy BDB DOI
PubMed
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Target
RAC-alpha serine/threonine-protein kinase
(Human)
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM16938
(5-{5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]pyridi...)
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Affinity Data
IC50: 1.5nM
Assay Description:
Inhibition of Akt
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
8/29/2010
Entry Details
Article
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PubMed
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Target
RAC-alpha serine/threonine-protein kinase
(Human)
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM16785
(5-{5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]pyridi...)
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Affinity Data
IC50: 1.80nM
Assay Description:
Inhibition of Akt
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
8/29/2010
Entry Details
Article
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PubMed
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Target
RAC-alpha serine/threonine-protein kinase
(Human)
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM16954
(6-{5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]-2-chl...)
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Affinity Data
IC50: 1.80nM
Assay Description:
Inhibition of Akt
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
8/29/2010
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
RAC-alpha serine/threonine-protein kinase
(Human)
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM16956
(6-{5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]-2-eth...)
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Affinity Data
IC50: 2nM
Assay Description:
Inhibition of Akt
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
8/29/2010
Entry Details
Article
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PubMed
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Target
RAC-alpha serine/threonine-protein kinase
(Human)
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM15067
(13a (S-) | 6-{5-[(2S)-2-amino-3-(1H-indol-3-yl)pro...)
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Affinity Data
IC50: 2nM
Assay Description:
Inhibition of Akt
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
8/29/2010
Entry Details
Article
Copy BDB DOI
PubMed
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Target
RAC-alpha serine/threonine-protein kinase
(Human)
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM50298479
((S)-1-(4-fluoro-3-methylphenyl)-3-(5-(3-methyl-1H-...)
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Affinity Data
IC50: 2.5nM
Assay Description:
Inhibition of Akt
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
8/29/2010
Entry Details
Article
Copy BDB DOI
PubMed
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Target
RAC-alpha serine/threonine-protein kinase
(Human)
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM50298462
((S)-1-(5-(3-cyclopropyl-1H-indazol-5-yl)pyridin-3-...)
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Affinity Data
IC50: 2.60nM
Assay Description:
Inhibition of Akt
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
8/29/2010
Entry Details
Article
Copy BDB DOI
PubMed
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Target
RAC-alpha serine/threonine-protein kinase
(Human)
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM50298458
((S)-5-(5-(2-amino-3-(1H-indol-3-yl)propoxy)pyridin...)
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Affinity Data
IC50: 2.90nM
Assay Description:
Inhibition of Akt
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
8/29/2010
Entry Details
Article
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PubMed
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Target
RAC-alpha serine/threonine-protein kinase
(Human)
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM16923
(5-{5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]pyridi...)
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Affinity Data
IC50: 3.20nM
Assay Description:
Inhibition of Akt
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
8/29/2010
Entry Details
Article
Copy BDB DOI
PubMed
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Target
RAC-alpha serine/threonine-protein kinase
(Human)
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM50298434
(5-(5-((S)-2-amino-3-(1H-indol-3-yl)propoxy)pyridin...)
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Affinity Data
IC50: 3.30nM
Assay Description:
Inhibition of Akt
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
8/29/2010
Entry Details
Article
Copy BDB DOI
PubMed
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Target
RAC-alpha serine/threonine-protein kinase
(Human)
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM16978
(6-{5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]pyridi...)
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Affinity Data
IC50: 3.40nM
Assay Description:
Inhibition of Akt
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
8/29/2010
Entry Details
Article
Copy BDB DOI
PubMed
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Target
RAC-alpha serine/threonine-protein kinase
(Human)
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM16968
(6-{5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]pyridi...)
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Affinity Data
IC50: 3.5nM
Assay Description:
Inhibition of Akt
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
8/29/2010
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
RAC-alpha serine/threonine-protein kinase
(Human)
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM50298478
((S)-1-(5-fluoro-2-methylphenyl)-3-(5-(3-methyl-1H-...)
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Affinity Data
IC50: 3.90nM
Assay Description:
Inhibition of Akt
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
8/29/2010
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
RAC-alpha serine/threonine-protein kinase
(Human)
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM50298460
((S)-1-(1H-indol-3-yl)-3-(5-(3-phenyl-1H-indazol-5-...)
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Affinity Data
IC50: 3.90nM
Assay Description:
Inhibition of Akt
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
8/29/2010
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
RAC-alpha serine/threonine-protein kinase
(Human)
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM16934
(5-{5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]pyridi...)
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Affinity Data
IC50: 4nM
Assay Description:
Inhibition of Akt
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
8/29/2010
Entry Details
Article
Copy BDB DOI
PubMed
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Target
RAC-alpha serine/threonine-protein kinase
(Human)
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM16930
(6-(5-{[(2S)-2-amino-3-(1H-indol-3-yl)propyl]oxy}py...)
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Affinity Data
IC50: 4.30nM
Assay Description:
Inhibition of Akt
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
8/29/2010
Entry Details
Article
Copy BDB DOI
PubMed
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Target
RAC-alpha serine/threonine-protein kinase
(Human)
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM16955
(5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]-3-(isoqu...)
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Affinity Data
IC50: 4.60nM
Assay Description:
Inhibition of Akt
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
8/29/2010
Entry Details
Article
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PubMed
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Target
RAC-alpha serine/threonine-protein kinase
(Human)
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM50298477
((S)-1-(4-bromophenyl)-3-(5-(3-methyl-1H-pyrazolo[3...)
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Affinity Data
IC50: 5nM
Assay Description:
Inhibition of Akt
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
8/29/2010
Entry Details
Article
Copy BDB DOI
PubMed
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Target
RAC-alpha serine/threonine-protein kinase
(Human)
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM16925
(5-{5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]pyridi...)
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Affinity Data
IC50: 5.40nM
Assay Description:
Inhibition of Akt
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
8/29/2010
Entry Details
Article
Copy BDB DOI
PubMed
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Target
RAC-alpha serine/threonine-protein kinase
(Human)
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM50298435
(5-(5-((S)-2-amino-3-(1H-indol-3-yl)propoxy)pyridin...)
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Affinity Data
IC50: 5.90nM
Assay Description:
Inhibition of Akt
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
8/29/2010
Entry Details
Article
Copy BDB DOI
PubMed
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Target
RAC-alpha serine/threonine-protein kinase
(Human)
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM50298480
((S)-1-(4-fluoro-2-methylphenyl)-3-(5-(3-methyl-1H-...)
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Affinity Data
IC50: 6nM
Assay Description:
Inhibition of Akt
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
8/29/2010
Entry Details
Article
Copy BDB DOI
PubMed
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Target
RAC-alpha serine/threonine-protein kinase
(Human)
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM16795
(3-[(2S)-2-amino-3-phenylpropoxy]-5-[3-(furan-2-yl)...)
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Affinity Data
IC50: 6.10nM
Assay Description:
Inhibition of Akt
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
8/29/2010
Entry Details
Article
Copy BDB DOI
PubMed
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Target
RAC-alpha serine/threonine-protein kinase
(Human)
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM50298472
((S)-1-(5-(3-methyl-1H-pyrazolo[3,4-c]pyridin-5-yl)...)
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IC50: 6.80nM
Assay Description:
Inhibition of Akt
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Date in BDB:
8/29/2010
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Target
RAC-alpha serine/threonine-protein kinase
(Human)
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM16788
(5-{5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]pyridi...)
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IC50: 7.10nM
Assay Description:
Inhibition of Akt
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Date in BDB:
8/29/2010
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Target
RAC-alpha serine/threonine-protein kinase
(Human)
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM50298441
(5-(5-((S)-2-amino-3-(1H-indol-3-yl)propoxy)pyridin...)
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Affinity Data
IC50: 7.20nM
Assay Description:
Inhibition of Akt
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Target Info
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Date in BDB:
8/29/2010
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Target
RAC-alpha serine/threonine-protein kinase
(Human)
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM16924
(5-{5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]pyridi...)
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IC50: 7.40nM
Assay Description:
Inhibition of Akt
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Date in BDB:
8/29/2010
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Target
RAC-alpha serine/threonine-protein kinase
(Human)
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM50298439
(5-(5-((S)-2-amino-3-(1H-indol-3-yl)propoxy)pyridin...)
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Affinity Data
IC50: 8.20nM
Assay Description:
Inhibition of Akt
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Date in BDB:
8/29/2010
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Target
RAC-alpha serine/threonine-protein kinase
(Human)
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM50298467
((S)-1-(3-fluorophenyl)-3-(5-(3-methyl-1H-pyrazolo[...)
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Affinity Data
IC50: 8.40nM
Assay Description:
Inhibition of Akt
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Target Info
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Date in BDB:
8/29/2010
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Target
RAC-alpha serine/threonine-protein kinase
(Human)
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM50298463
((S)-1-(1H-indol-3-yl)-3-(5-(3-(thiazol-2-yl)-1H-in...)
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Affinity Data
IC50: 9.80nM
Assay Description:
Inhibition of Akt
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Date in BDB:
8/29/2010
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Target
RAC-alpha serine/threonine-protein kinase
(Human)
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM50298446
(5-(5-((S)-2-amino-3-(1H-indol-3-yl)propoxy)pyridin...)
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Affinity Data
IC50: 10nM
Assay Description:
Inhibition of Akt
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Date in BDB:
8/29/2010
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Target
RAC-alpha serine/threonine-protein kinase
(Human)
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM50298437
(5-(5-((S)-2-amino-3-(1H-indol-3-yl)propoxy)pyridin...)
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Affinity Data
IC50: 10.3nM
Assay Description:
Inhibition of Akt
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Date in BDB:
8/29/2010
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Target
RAC-alpha serine/threonine-protein kinase
(Human)
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM50298436
(5-(5-((S)-2-amino-3-(1H-indol-3-yl)propoxy)pyridin...)
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IC50: 10.4nM
Assay Description:
Inhibition of Akt
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Target Info
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Date in BDB:
8/29/2010
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Target
RAC-alpha serine/threonine-protein kinase
(Human)
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM16960
(6-{5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]-6-chl...)
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Affinity Data
IC50: 12nM
Assay Description:
Inhibition of Akt
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Date in BDB:
8/29/2010
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Target
RAC-alpha serine/threonine-protein kinase
(Human)
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM50298476
((S)-1-(5-(3-methyl-1H-pyrazolo[3,4-c]pyridin-5-yl)...)
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Affinity Data
IC50: 12nM
Assay Description:
Inhibition of Akt
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Target Info
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Date in BDB:
8/29/2010
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Target
RAC-alpha serine/threonine-protein kinase
(Human)
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM16794
(3-[(2S)-2-amino-3-phenylpropoxy]-5-{3-ethenyl-1H-p...)
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Affinity Data
IC50: 13nM
Assay Description:
Inhibition of Akt
More data for this Ligand-Target Pair
Target Info
PDB
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Date in BDB:
8/29/2010
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