Compile Data Set for Download or QSAR
Report error Found 51 Enz. Inhib. hit(s) with all data for entry = 50030303
TargetTyrosine-protein kinase ABL1(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293993((E)-3-(2-(Purin-9-yl)vinyl)-4-methyl-N-(4-(trifluo...)
Affinity DataIC50: 38nMAssay Description:Inhibition of wild type human Abl kinase by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293992(AP24348 | CHEMBL559838 | (E)-3-(2-(Purin-9-yl)viny...)
Affinity DataIC50: 48nMAssay Description:Inhibition of wild type human Abl kinase by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293992(AP24348 | CHEMBL559838 | (E)-3-(2-(Purin-9-yl)viny...)
Affinity DataIC50: 84nMAssay Description:Inhibition of human Src kinase by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM13530(cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...)
Affinity DataIC50: 160nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293993((E)-3-(2-(Purin-9-yl)vinyl)-4-methyl-N-(4-(trifluo...)
Affinity DataIC50: 307nMAssay Description:Inhibition of human Src kinase by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293999((E)-N-(3-(2-(6-(4-(Dimethylphosphoryl)phenylamino)...)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of human Src kinase by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293997((E)-N-(4-Methyl-3-(2-(6-(pyrid-4-yl-amino)-9H-puri...)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of human Src kinase by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50294005((E)-3-(2-(6-(Cyclopropylamino)-9H-purin-9-yl)vinyl...)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of human Src kinase by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293999((E)-N-(3-(2-(6-(4-(Dimethylphosphoryl)phenylamino)...)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of wild type human Abl kinase by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50294008((E)-3-(2-(6-(Cyclopropylamino)-9H-purin-9-yl)vinyl...)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of human Src kinase by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50294010((E)-3-(2-(6-(Cyclopropylamino)-9H-purin-9-yl)vinyl...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human Src kinase by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50294011((E)-3-(2-(6-(cyclopropylamino)-9H-purin-9-yl)vinyl...)
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of human Src kinase by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50294012(N-(3-(1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of human Src kinase by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293996((E)-N-(4-Methyl-3-(2-(6-(pyrid-3-yl-amino)-9H-puri...)
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of human Src kinase by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293997((E)-N-(4-Methyl-3-(2-(6-(pyrid-4-yl-amino)-9H-puri...)
Affinity DataIC50: 9.90E+3nMAssay Description:Inhibition of wild type human Abl kinase by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50294001((E)-3-(2-(6-(Cyclopropylamino)-9H-purin-9-yl)vinyl...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human Src kinase by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50294012(N-(3-(1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of wild type human Abl kinase by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50294010((E)-3-(2-(6-(Cyclopropylamino)-9H-purin-9-yl)vinyl...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of wild type human Abl kinase by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50294008((E)-3-(2-(6-(Cyclopropylamino)-9H-purin-9-yl)vinyl...)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of wild type human Abl kinase by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50294001((E)-3-(2-(6-(Cyclopropylamino)-9H-purin-9-yl)vinyl...)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of wild type human Abl kinase by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50294014((E)-3-(2-(6-(Cyclopropylamino)-9H-purin-9-yl)vinyl...)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of wild type human Abl kinase by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50294011((E)-3-(2-(6-(cyclopropylamino)-9H-purin-9-yl)vinyl...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of wild type human Abl kinase by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50294016((E)-N-(4-Methyl-3-(2-(6-(methylamino)-9Hpurin-9-yl...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of wild type human Abl kinase by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293998((E)-N-(4-Methyl-3-(2-(6-(pyrimid-4-yl-amino)-9H-pu...)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of human Src kinase by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293996((E)-N-(4-Methyl-3-(2-(6-(pyrid-3-yl-amino)-9H-puri...)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of wild type human Abl kinase by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50294013((E)-3-(2-(6-(Cyclopropylamino)-9H-purin-9-yl)vinyl...)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human Src kinase by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50294004((E)-3-(2-(6-(Cyclopropylamino)-9H-purin-9-yl)vinyl...)
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of wild type human Abl kinase by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293998((E)-N-(4-Methyl-3-(2-(6-(pyrimid-4-yl-amino)-9H-pu...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of wild type human Abl kinase by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50294014((E)-3-(2-(6-(Cyclopropylamino)-9H-purin-9-yl)vinyl...)
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of human Src kinase by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50294004((E)-3-(2-(6-(Cyclopropylamino)-9H-purin-9-yl)vinyl...)
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of human Src kinase by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50294009((E)-3-(2-(6-(Cyclopropylamino)-9H-purin-9-yl)vinyl...)
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibition of human Src kinase by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50294006((E)-3-(2-(6-(Cyclopropylamino)-9H-purin-9-yl)vinyl...)
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibition of human Src kinase by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50294016((E)-N-(4-Methyl-3-(2-(6-(methylamino)-9Hpurin-9-yl...)
Affinity DataIC50: 5.20E+4nMAssay Description:Inhibition of human Src kinase by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50294005((E)-3-(2-(6-(Cyclopropylamino)-9H-purin-9-yl)vinyl...)
Affinity DataIC50: 5.90E+4nMAssay Description:Inhibition of wild type human Abl kinase by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50294006((E)-3-(2-(6-(Cyclopropylamino)-9H-purin-9-yl)vinyl...)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of wild type human Abl kinase by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50294002((E)-1-(3-(2-(6-(Cyclopropylamino)-9H-purin-9-yl)vi...)
Affinity DataIC50: 6.20E+4nMAssay Description:Inhibition of wild type human Abl kinase by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50294013((E)-3-(2-(6-(Cyclopropylamino)-9H-purin-9-yl)vinyl...)
Affinity DataIC50: 7.20E+4nMAssay Description:Inhibition of wild type human Abl kinase by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293994((E)-N-(4-Methyl-3-(2-(6-(cyclopropylamino)-9H-puri...)
Affinity DataIC50: 7.40E+4nMAssay Description:Inhibition of wild type human Abl kinase by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50294003((E)-3-(2-(6-(Cyclopropylamino)-9H-purin-9-yl)vinyl...)
Affinity DataIC50: 8.60E+4nMAssay Description:Inhibition of human Src kinase by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293994((E)-N-(4-Methyl-3-(2-(6-(cyclopropylamino)-9H-puri...)
Affinity DataIC50: 9.10E+4nMAssay Description:Inhibition of human Src kinase by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50294015(N-(4-Methyl-3-(2-(6-(methylamino)-9H-purin-9-yl)et...)
Affinity DataIC50: 9.60E+4nMAssay Description:Inhibition of wild type human Abl kinase by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50294009((E)-3-(2-(6-(Cyclopropylamino)-9H-purin-9-yl)vinyl...)
Affinity DataIC50: 1.46E+5nMAssay Description:Inhibition of wild type human Abl kinase by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50294000((E)-N-(4-Methyl-3-(2-(6-(3-(N',N''-dimethylamino)p...)
Affinity DataIC50: 1.57E+5nMAssay Description:Inhibition of wild type human Abl kinase by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50294000((E)-N-(4-Methyl-3-(2-(6-(3-(N',N''-dimethylamino)p...)
Affinity DataIC50: 1.59E+5nMAssay Description:Inhibition of human Src kinase by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293995((E)-N-(4-Methyl-3-(2-(6-(pyridine-2-yl-amino)-9H-p...)
Affinity DataIC50: 2.01E+5nMAssay Description:Inhibition of human Src kinase by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50294003((E)-3-(2-(6-(Cyclopropylamino)-9H-purin-9-yl)vinyl...)
Affinity DataIC50: 2.36E+5nMAssay Description:Inhibition of wild type human Abl kinase by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293995((E)-N-(4-Methyl-3-(2-(6-(pyridine-2-yl-amino)-9H-p...)
Affinity DataIC50: 2.43E+5nMAssay Description:Inhibition of wild type human Abl kinase by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50294007((E)-3-(2-(6-(Cyclopropylamino)-9H-purin-9-yl)vinyl...)
Affinity DataIC50: 2.67E+5nMAssay Description:Inhibition of wild type human Abl kinase by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50294015(N-(4-Methyl-3-(2-(6-(methylamino)-9H-purin-9-yl)et...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human Src kinase by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50294007((E)-3-(2-(6-(Cyclopropylamino)-9H-purin-9-yl)vinyl...)
Affinity DataIC50: 3.10E+5nMAssay Description:Inhibition of human Src kinase by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
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