Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50030707
TargetMu-type opioid receptor(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50300357((S)-2-((S)-1-((2S,8S,11R)-11-((S)-2-amino-3-(4-hyd...)
Affinity DataIC50: 0.110nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor expressed in CHO cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50300359((S)-2-((S)-1-((2S,8S,11R,14S)-14-amino-8-benzyl-11...)
Affinity DataIC50: 0.380nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor expressed in CHO cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50059841(CHEMBL278789 | (S)-1-[(S)-2-[2-((S)-2-{(R)-2-[(S)-...)
Affinity DataIC50: 0.720nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor expressed in CHO cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50300356((S)-2-((S)-1-((2S,8S,11R,14S)-14-amino-8-benzyl-11...)
Affinity DataIC50: 0.810nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor expressed in CHO cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50247803(Beta-Funeltrexamine | beta-funaltrexamine | methyl...)
Affinity DataIC50: 2.20nMAssay Description:Displacement of beta-[3H]FNA from mu opioid receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50300356((S)-2-((S)-1-((2S,8S,11R,14S)-14-amino-8-benzyl-11...)
Affinity DataIC50: 2.20nMAssay Description:Displacement of beta-[3H]FNA from mu opioid receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50300358((S)-2-((S)-1-((2S,8S,11R)-15-acetyl-11-((S)-2-amin...)
Affinity DataIC50: 4.30nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor expressed in CHO cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50300360((S)-2-((S)-1-((2S,8S,11R)-11-((S)-2-amino-3-(4-hyd...)
Affinity DataIC50: 5.20nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor expressed in CHO cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50300362((S)-2-amino-3-(4-hydroxyphenyl)-N-((S)-1-(2-((S)-1...)
Affinity DataIC50: 12nMAssay Description:Inhibition of radiolabeled [D-Ala2,MePhe4,Gly-ol5]enkephalin binding to delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50300356((S)-2-((S)-1-((2S,8S,11R,14S)-14-amino-8-benzyl-11...)
Affinity DataIC50: 24nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor expressed in CHO cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50300361((S)-2-((S)-1-((2S,8S,11R)-16-acetyl-11-((S)-2-amin...)
Affinity DataIC50: 30nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor expressed in CHO cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50300359((S)-2-((S)-1-((2S,8S,11R,14S)-14-amino-8-benzyl-11...)
Affinity DataIC50: 97nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor expressed in CHO cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50059841(CHEMBL278789 | (S)-1-[(S)-2-[2-((S)-2-{(R)-2-[(S)-...)
Affinity DataIC50: 197nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor expressed in CHO cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50300358((S)-2-((S)-1-((2S,8S,11R)-15-acetyl-11-((S)-2-amin...)
Affinity DataIC50: 272nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor expressed in CHO cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50300357((S)-2-((S)-1-((2S,8S,11R)-11-((S)-2-amino-3-(4-hyd...)
Affinity DataIC50: 342nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor expressed in CHO cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50300360((S)-2-((S)-1-((2S,8S,11R)-11-((S)-2-amino-3-(4-hyd...)
Affinity DataIC50: 382nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor expressed in CHO cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50300361((S)-2-((S)-1-((2S,8S,11R)-16-acetyl-11-((S)-2-amin...)
Affinity DataIC50: 436nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor expressed in CHO cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50300363(Tyr-D-Ala-Gly-NMePhe | CHEMBL583426)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of [3H]naloxone binding to mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50300362((S)-2-amino-3-(4-hydroxyphenyl)-N-((S)-1-(2-((S)-1...)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of [3H]naloxone binding to mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed