Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50030774
TargetTransporter(Rat)
University of Glasgow

Curated by ChEMBL
LigandPNGBDBM50198230((S)-2-((S)-(2-iodophenoxy)(phenyl)methyl)morpholin...)
Affinity DataKi:  0.840nMAssay Description:Displacement of [3H]nisoxetine from NAT in Sprague-Dawley rat brain after 4 hrs by liquid scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTransporter(Rat)
University of Glasgow

Curated by ChEMBL
LigandPNGBDBM50301211((2R,3S)-2-[(2-Iodophenoxy)phenylmethyl]morpholine ...)
Affinity DataKi:  8.40nMAssay Description:Displacement of [3H]nisoxetine from NAT in Sprague-Dawley rat brain after 4 hrs by liquid scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
University of Glasgow

Curated by ChEMBL
LigandPNGBDBM50301213((2R,3S)-2-[(4-Iodophenoxy)phenylmethyl]morpholine ...)
Affinity DataKi:  34.5nMAssay Description:Displacement of [3H]citalopram from SERT in Sprague-Dawley rat brain after 2 hrs by liquid scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
University of Glasgow

Curated by ChEMBL
LigandPNGBDBM50301211((2R,3S)-2-[(2-Iodophenoxy)phenylmethyl]morpholine ...)
Affinity DataKi:  51.5nMAssay Description:Displacement of [3H]citalopram from SERT in Sprague-Dawley rat brain after 2 hrs by liquid scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTransporter(Rat)
University of Glasgow

Curated by ChEMBL
LigandPNGBDBM50264064((S)-2-((S)-(2-ethoxyphenoxy)(4-iodophenyl)methyl)m...)
Affinity DataKi:  53.8nMAssay Description:Displacement of [3H]nisoxetine from NAT in Sprague-Dawley rat brain after 4 hrs by liquid scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTransporter(Rat)
University of Glasgow

Curated by ChEMBL
LigandPNGBDBM50264063((2R,3S)-iodoreboxetine | (R)-2-((S)-(2-ethoxypheno...)
Affinity DataKi:  58.2nMAssay Description:Displacement of [3H]nisoxetine from NAT in Sprague-Dawley rat brain after 4 hrs by liquid scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
University of Glasgow

Curated by ChEMBL
LigandPNGBDBM50301212((2R,3S)-2-[(3-Iodophenoxy)phenylmethyl]morpholine ...)
Affinity DataKi:  154nMAssay Description:Displacement of [3H]citalopram from SERT in Sprague-Dawley rat brain after 2 hrs by liquid scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
University of Glasgow

Curated by ChEMBL
LigandPNGBDBM50301211((2R,3S)-2-[(2-Iodophenoxy)phenylmethyl]morpholine ...)
Affinity DataKi:  526nMAssay Description:Displacement of [3H]WIN-35428 from DAT in Sprague-Dawley rat brain after 2 hrs by liquid scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTransporter(Rat)
University of Glasgow

Curated by ChEMBL
LigandPNGBDBM50301213((2R,3S)-2-[(4-Iodophenoxy)phenylmethyl]morpholine ...)
Affinity DataKi:  1.10E+3nMAssay Description:Displacement of [3H]nisoxetine from NAT in Sprague-Dawley rat brain after 4 hrs by liquid scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTransporter(Rat)
University of Glasgow

Curated by ChEMBL
LigandPNGBDBM50301212((2R,3S)-2-[(3-Iodophenoxy)phenylmethyl]morpholine ...)
Affinity DataKi:  1.70E+3nMAssay Description:Displacement of [3H]nisoxetine from NAT in Sprague-Dawley rat brain after 4 hrs by liquid scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
University of Glasgow

Curated by ChEMBL
LigandPNGBDBM50301212((2R,3S)-2-[(3-Iodophenoxy)phenylmethyl]morpholine ...)
Affinity DataKi:  1.90E+3nMAssay Description:Displacement of [3H]WIN-35428 from DAT in Sprague-Dawley rat brain after 2 hrs by liquid scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
University of Glasgow

Curated by ChEMBL
LigandPNGBDBM50301213((2R,3S)-2-[(4-Iodophenoxy)phenylmethyl]morpholine ...)
Affinity DataKi:  2.10E+3nMAssay Description:Displacement of [3H]WIN-35428 from DAT in Sprague-Dawley rat brain after 2 hrs by liquid scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed