Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50030923
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rat)
Emory University

Curated by ChEMBL
LigandPNGBDBM50304085(N-(2-(3,4-Dichlorophenylamino)ethyl)-2-(4-(methyls...)
Affinity DataIC50: 57nMAssay Description:Antagonist activity at wild type rat NR1/NR2B receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induced curren...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rat)
Emory University

Curated by ChEMBL
LigandPNGBDBM50304085(N-(2-(3,4-Dichlorophenylamino)ethyl)-2-(4-(methyls...)
Affinity DataIC50: 57nMAssay Description:Antagonist activity at rat recombinant NR1/NR2B receptor expressed in frog oocytes assessed as inhibition of glutamate/glycine-induced current by two...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
Emory University

Curated by ChEMBL
LigandPNGBDBM50304085(N-(2-(3,4-Dichlorophenylamino)ethyl)-2-(4-(methyls...)
Affinity DataIC50: 5.80E+4nMAssay Description:Antagonist activity at rat recombinant NR1/NR2C receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induced curr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rat)
Emory University

Curated by ChEMBL
LigandPNGBDBM50304085(N-(2-(3,4-Dichlorophenylamino)ethyl)-2-(4-(methyls...)
Affinity DataIC50: 8.20E+4nMAssay Description:Antagonist activity at rat recombinant NR1/NR2A receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induced curr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50304090(N-(4-(3-(2-(3,4-Dichlorophenylamino)ethylamino)-pr...)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]astemizole from human recombinant ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Emory University

Curated by ChEMBL
LigandPNGBDBM50304085(N-(2-(3,4-Dichlorophenylamino)ethyl)-2-(4-(methyls...)
Affinity DataKi:  119nMAssay Description:Displacement of [3H]ifenprodil form NR2B receptor in Wistar rat cerebral cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Emory University

Curated by ChEMBL
LigandPNGBDBM50304087(N-(4-(2-(3-(3,4-Dichlorophenyl)-2-oxoimidazolidin-...)
Affinity DataKi:  300nMAssay Description:Displacement of [3H]ifenprodil form NR2B receptor in Wistar rat cerebral cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50304088(N-(4-(2-(2-(3,4-Dichlorophenylamino)ethylamino)-et...)
Affinity DataKi:  300nMAssay Description:Displacement of [3H]astemizole from human recombinant ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Emory University

Curated by ChEMBL
LigandPNGBDBM50304086(N-(4-(2-(4-(3,4-Dichlorophenyl)piperazin-1-yl)-2-o...)
Affinity DataKi:  817nMAssay Description:Displacement of [3H]ifenprodil form NR2B receptor in Wistar rat cerebral cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50304091(N-(3,4-Dichlorocinnamyl)-3-(4-(methylsulfonamido)-...)
Affinity DataKi:  3.00E+3nMAssay Description:Displacement of [3H]astemizole from human recombinant ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50304089(N-(2-(3,4-Dichlorophenylamino)ethyl)-3-(4-(methyls...)
Affinity DataKi:  4.62E+3nMAssay Description:Displacement of [3H]astemizole from human recombinant ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed