Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50030712
TargetHistone acetyltransferase KAT2B(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50247839(methyl 3-(5-chloro-3-oxoisothiazol-2(3H)-yl)propan...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human recombinant histone acetyltransferase PCAF assessed as CoA-SH activity preincubated for 15 mins by CPM fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT2B(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50300427(4,5-Dichloro-2-ethylisothiazol-3(2H)-one | CHEMBL5...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human recombinant histone acetyltransferase PCAF assessed as CoA-SH activity preincubated for 15 mins by CPM fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT2B(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50300425(Methyl 3-(4,5-dichloro-3-oxoisothiazol-2(3H)-yl)pr...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human recombinant histone acetyltransferase PCAF assessed as CoA-SH activity preincubated for 15 mins by CPM fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT2B(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50247820(5-Chloro-2-ethylisothiazol-3(2H)-one | CHEMBL46147...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human recombinant histone acetyltransferase PCAF assessed as CoA-SH activity preincubated for 15 mins by CPM fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT2B(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50247869(methyl 3-(5-chloro-1-oxido-3-oxoisothiazol-2(3H)-y...)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human recombinant histone acetyltransferase PCAF assessed as CoA-SH activity preincubated for 15 mins by CPM fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT2B(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50300419(Methyl 3-(5-chloro-4-methyl-1-oxido-3-oxoisothiazo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant histone acetyltransferase PCAF assessed as CoA-SH activity preincubated for 15 mins by CPM fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT2B(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50300418(2-Tert-butyl-5-chloroisothiazol-3(2H)-one 1-oxide ...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant histone acetyltransferase PCAF assessed as CoA-SH activity preincubated for 15 mins by CPM fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT2B(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50300417(2-Tert-butyl-5-(dodecylthio)isothiazol-3(2H)-one-1...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant histone acetyltransferase PCAF assessed as CoA-SH activity preincubated for 15 mins by CPM fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT2B(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50300416(Methyl 3-[5-(dodecylthio)-1-oxido-3-oxoisothiazol-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant histone acetyltransferase PCAF assessed as CoA-SH activity preincubated for 15 mins by CPM fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT2B(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50300422(4,5-Dichloro-2-ethylisothiazol-3(2H)-one-1-oxide |...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant histone acetyltransferase PCAF assessed as CoA-SH activity preincubated for 15 mins by CPM fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT2B(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50300421(5-Chloro-2-ethyl-4-methylisothiazol-3(2H)-one-1-ox...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant histone acetyltransferase PCAF assessed as CoA-SH activity preincubated for 15 mins by CPM fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT2B(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50300420(Methyl 3-(4,5-dichloro-1-oxido-3-oxoisothiazol-2(3...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant histone acetyltransferase PCAF assessed as CoA-SH activity preincubated for 15 mins by CPM fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT2B(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50300424(Methyl 3-(5-chloro-4-methyl-3-oxoisothiazol-2(3H)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant histone acetyltransferase PCAF assessed as CoA-SH activity preincubated for 15 mins by CPM fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT2B(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50300423(5-Chloro-2-ethylisothiazol-3(2H)-one-1-oxide | CHE...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant histone acetyltransferase PCAF assessed as CoA-SH activity preincubated for 15 mins by CPM fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT2B(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50300415(Methyl 3-[4-chloro-5-(dodecylthio)-1-oxido-3-oxois...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant histone acetyltransferase PCAF assessed as CoA-SH activity preincubated for 15 mins by CPM fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT2B(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50300426(5-Chloro-2-ethyl-4-methylisothiazol-3(2H)-one | CH...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant histone acetyltransferase PCAF assessed as CoA-SH activity preincubated for 15 mins by CPM fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed