Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50030719
TargetSodium/glucose cotransporter 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50300462((2R,3'R,4'S,5'S,6'R)-6-chloro-5-(4-ethylbenzyl)-6'...)
Affinity DataIC50: 6.60nMAssay Description:Inhibition of human SGLT2 expressed in HEK293.ETN cells assessed as methyl-alpha-D-[U-14C]glucopyranoside uptake by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM20880(CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...)
Affinity DataIC50: 6.70nMAssay Description:Inhibition of human SGLT2 expressed in HEK293.ETN cells assessed as methyl-alpha-D-[U-14C]glucopyranoside uptake by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium/glucose cotransporter 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50300461((2R,3'R,4'S,5'S,6'R)-5-(4-ethoxybenzyl)-6'-(hydrox...)
Affinity DataIC50: 71nMAssay Description:Inhibition of human SGLT2 expressed in HEK293.ETN cells assessed as methyl-alpha-D-[U-14C]glucopyranoside uptake by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50300462((2R,3'R,4'S,5'S,6'R)-6-chloro-5-(4-ethylbenzyl)-6'...)
Affinity DataIC50: 620nMAssay Description:Inhibition of human SGLT1 expressed in african green monkey COS7 cells assessed as methyl-alpha-D-[U-14C]glucopyranoside uptake by scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM20880(CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...)
Affinity DataIC50: 885nMAssay Description:Inhibition of human SGLT1 expressed in african green monkey COS7 cells assessed as methyl-alpha-D-[U-14C]glucopyranoside uptake by scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50300461((2R,3'R,4'S,5'S,6'R)-5-(4-ethoxybenzyl)-6'-(hydrox...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human SGLT1 expressed in african green monkey COS7 cells assessed as methyl-alpha-D-[U-14C]glucopyranoside uptake by scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed