Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50030811
TargetGenome polyprotein(HCV)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50301911(N-{3-[(S)-5-tert-Butyl-1-(4-fluoro-benzyl)-4-hydro...)
Affinity DataIC50: 2nMAssay Description:Inhibition of HSV 1b con1 NS5B polymerase assessed as [3H]UTP incorporation into acid insoluble RNA productMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50301902(N-{3-[(S)-5-tert-Butyl-1-(4-fluoro-3-methyl-benzyl...)
Affinity DataIC50: 3nMAssay Description:Inhibition of HSV 1b con1 NS5B polymerase assessed as [3H]UTP incorporation into acid insoluble RNA productMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50301903(N-{3-[(S)-5-tert-Butyl-1-(4-fluoro-3-methoxy-benzy...)
Affinity DataIC50: 4nMAssay Description:Inhibition of HSV 1b con1 NS5B polymerase assessed as [3H]UTP incorporation into acid insoluble RNA productMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50301914(N-{2-Acetyl-3-[(S)-5-tert-butyl-1-(4-fluoro-benzyl...)
Affinity DataIC50: 4nMAssay Description:Inhibition of HSV 1b con1 NS5B polymerase assessed as [3H]UTP incorporation into acid insoluble RNA productMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50301901(N-{3-[(S)-5-tert-Butyl-1-(3-chloro-4-fluoro-benzyl...)
Affinity DataIC50: 5nMAssay Description:Inhibition of HSV 1b con1 NS5B polymerase assessed as [3H]UTP incorporation into acid insoluble RNA productMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50301906(N-{3-[(S)-5-tert-Butyl-4-hydroxy-1-(3-methyl-butyl...)
Affinity DataIC50: 5nMAssay Description:Inhibition of HSV 1b con1 NS5B polymerase assessed as [3H]UTP incorporation into acid insoluble RNA productMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50301913(N-{3-[(S)-5-tert-Butyl-1-(4-fluoro-benzyl)-4-hydro...)
Affinity DataIC50: 6nMAssay Description:Inhibition of HSV 1b con1 NS5B polymerase assessed as [3H]UTP incorporation into acid insoluble RNA productMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50301900(N-{3-[(S)-5-tert-Butyl-1-(4-fluoro-benzyl)-4-hydro...)
Affinity DataIC50: 7nMAssay Description:Inhibition of HSV 1b con1 NS5B polymerase assessed as [3H]UTP incorporation into acid insoluble RNA productMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50301899(N-[3-((S)-1-Benzyl-5-tert-butyl-4-hydroxy-2-oxo-2,...)
Affinity DataIC50: 8nMAssay Description:Inhibition of HSV 1b con1 NS5B polymerase assessed as [3H]UTP incorporation into acid insoluble RNA productMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50301907(N-{3-[(S)-5-tert-Butyl-1-(3,3-dimethyl-butyl)-4-hy...)
Affinity DataIC50: 8nMAssay Description:Inhibition of HSV 1b con1 NS5B polymerase assessed as [3H]UTP incorporation into acid insoluble RNA productMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50301916(N-{3-[(S)-5-tert-Butyl-1-(4-fluoro-benzyl)-4-hydro...)
Affinity DataIC50: 9nMAssay Description:Inhibition of HSV 1b con1 NS5B polymerase assessed as [3H]UTP incorporation into acid insoluble RNA productMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50301912(N-{3-[(S)-5-tert-Butyl-1-(4-fluoro-benzyl)-4-hydro...)
Affinity DataIC50: 10nMAssay Description:Inhibition of HSV 1b con1 NS5B polymerase assessed as [3H]UTP incorporation into acid insoluble RNA productMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50301915(3-[(S)-5-tert-Butyl-1-(4-fluoro-benzyl)-4-hydroxy-...)
Affinity DataIC50: 11nMAssay Description:Inhibition of HSV 1b con1 NS5B polymerase assessed as [3H]UTP incorporation into acid insoluble RNA productMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50301917(N-{3-[(S)-5-(1,1-Dimethyl-propyl)-1-(4-fluoro-3-me...)
Affinity DataIC50: 13nMAssay Description:Inhibition of HSV 1b con1 NS5B polymerase assessed as [3H]UTP incorporation into acid insoluble RNA productMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50301904(N-{3-[(S)-5-tert-Butyl-1-(2,4-difluoro-benzyl)-4-h...)
Affinity DataIC50: 13nMAssay Description:Inhibition of HSV 1b con1 NS5B polymerase assessed as [3H]UTP incorporation into acid insoluble RNA productMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50301905(N-{3-[(S)-5-tert-Butyl-1-(5-fluoro-pyridin-2-ylmet...)
Affinity DataIC50: 42nMAssay Description:Inhibition of HSV 1b con1 NS5B polymerase assessed as [3H]UTP incorporation into acid insoluble RNA productMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50301908((S)-5-tert-Butyl-1-(4-fluoro-benzyl)-3-(7-fluoro-1...)
Affinity DataIC50: 338nMAssay Description:Inhibition of HSV 1b con1 NS5B polymerase assessed as [3H]UTP incorporation into acid insoluble RNA productMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50301909(3-[(S)-5-tert-Butyl-1-(4-fluoro-benzyl)-4-hydroxy-...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of HSV 1b con1 NS5B polymerase assessed as [3H]UTP incorporation into acid insoluble RNA productMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50301910((S)-5-tert-Butyl-1-(4-fluoro-benzyl)-4-hydroxy-3-(...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of HSV 1b con1 NS5B polymerase assessed as [3H]UTP incorporation into acid insoluble RNA productMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed