Compile Data Set for Download or QSAR
Report error Found 62 Enz. Inhib. hit(s) with all data for entry = 50031317
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50311061(3-(3-fluoro-9H-benzo[f]imidazo[1,5-a][1,2,4]triazo...)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]Flumazenil from cloned human GABA alpha-5-beta-3-gamma-2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50311052(ethyl 3-fluoro-9H-benzo[f]imidazo[1,5-a][1,2,4]tri...)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]Flumazenil from human GABA alpha-5-beta-3-gamma-2 receptor expressed in insect SF9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50311049(10-chloro-9H-benzo[f]imidazo[1,5-a][1,2,4]triazolo...)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]Flumazenil from cloned human GABA alpha-5-beta-3-gamma-2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50311048(10-chloro-3-fluoro-9H-benzo[f]imidazo[1,5-a][1,2,4...)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]Flumazenil from human GABA alpha-5-beta-3-gamma-2 receptor expressed in insect SF9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50311074(4-fluoro-10-methyl-9H-benzo[f]imidazo[1,5-a][1,2,4...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]Flumazenil from cloned human GABA alpha-5-beta-3-gamma-2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50311036(10-chloro-3-(difluoromethyl)-9H-benzo[f]imidazo[1,...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]Flumazenil from cloned human GABA alpha-5-beta-3-gamma-2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50311075(4-chloro-10-methyl-9H-benzo[f]imidazo[1,5-a][1,2,4...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]Flumazenil from cloned human GABA alpha-5-beta-3-gamma-2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50311037(10-chloro-3-cyclopropyl-9H-benzo[f]imidazo[1,5-a][...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]Flumazenil from cloned human GABA alpha-5-beta-3-gamma-2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50311033(3-bromo-10-chloro-9H-benzo[f]imidazo[1,5-a][1,2,4]...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]Flumazenil from cloned human GABA alpha-5-beta-3-gamma-2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50311057(3-chloro-10-propyl-9H-benzo[f]imidazo[1,5-a][1,2,4...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]Flumazenil from cloned human GABA alpha-5-beta-3-gamma-2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50311071(3-(difluoromethoxy)-10-methyl-9H-benzo[f]imidazo[1...)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]Flumazenil from cloned human GABA alpha-5-beta-3-gamma-2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50311035(10-chloro-3-methyl-9H-benzo[f]imidazo[1,5-a][1,2,4...)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]Flumazenil from cloned human GABA alpha-5-beta-3-gamma-2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50311047(Ro-4882224 | 3,10-dichloro-9H-benzo[f]imidazo[1,5-...)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]Flumazenil from cloned human GABA alpha-5-beta-3-gamma-2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50311068(3-(difluoromethyl)-10-methyl-9H-benzo[f]imidazo[1,...)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]Flumazenil from cloned human GABA alpha-5-beta-3-gamma-2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50311039(10-chloro-N-cyclopropyl-9H-benzo[f]imidazo[1,5-a][...)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]Flumazenil from cloned human GABA alpha-5-beta-3-gamma-2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50311034(10-chloro-9H-benzo[f]imidazo[1,5-a][1,2,4]triazolo...)
Affinity DataKi:  2.40nMAssay Description:Displacement of [3H]Flumazenil from cloned human GABA alpha-5-beta-3-gamma-2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50311054(1-(3-chloro-9H-benzo[f]imidazo[1,5-a][1,2,4]triazo...)
Affinity DataKi:  2.60nMAssay Description:Displacement of [3H]Flumazenil from human GABA alpha-5-beta-3-gamma-2 receptor expressed in insect SF9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50311064(10-methyl-9H-benzo[f]imidazo[1,5-a][1,2,4]triazolo...)
Affinity DataKi:  2.60nMAssay Description:Displacement of [3H]Flumazenil from cloned human GABA alpha-5-beta-3-gamma-2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50311040(N-(10-chloro-9H-benzo[f]imidazo[1,5-a][1,2,4]triaz...)
Affinity DataKi:  2.90nMAssay Description:Displacement of [3H]Flumazenil from cloned human GABA alpha-5-beta-3-gamma-2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50311065(3-fluoro-10-methyl-9H-benzo[f]imidazo[1,5-a][1,2,4...)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]Flumazenil from cloned human GABA alpha-5-beta-3-gamma-2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50311046(3-chloro-10-methyl-9H-benzo[f]imidazo[1,5-a][1,2,4...)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]Flumazenil from cloned human GABA alpha-5-beta-3-gamma-2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50311056(10-(1,1-difluoropropyl)-3-fluoro-9H-benzo[f]imidaz...)
Affinity DataKi:  3.20nMAssay Description:Displacement of [3H]Flumazenil from cloned human GABA alpha-5-beta-3-gamma-2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50311062(3-bromo-10-(thiophen-2-yl)-9H-benzo[f]imidazo[1,5-...)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]Flumazenil from cloned human GABA alpha-5-beta-3-gamma-2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50311066(3-iodo-10-methyl-9H-benzo[f]imidazo[1,5-a][1,2,4]t...)
Affinity DataKi:  4.40nMAssay Description:Displacement of [3H]Flumazenil from cloned human GABA alpha-5-beta-3-gamma-2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50311045(Ro-4938581 | 3-bromo-10-(difluoromethyl)-9H-benzo[...)
Affinity DataKi:  4.60nMAssay Description:Displacement of [3H]Flumazenil from cloned human GABA alpha-5-beta-3-gamma-2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50311044(3-chloro-10-(difluoromethyl)-9H-benzo[f]imidazo[1,...)
Affinity DataKi:  5.60nMAssay Description:Displacement of [3H]Flumazenil from cloned human GABA alpha-5-beta-3-gamma-2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50310939(3-bromo-10-methyl-9H-benzo[f]imidazo[1,5-a][1,2,4]...)
Affinity DataKi:  6.20nMAssay Description:Displacement of [3H]Flumazenil from cloned human GABA alpha-5-beta-3-gamma-2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50311038(10-chloro-3-phenyl-9H-benzo[f]imidazo[1,5-a][1,2,4...)
Affinity DataKi:  6.30nMAssay Description:Displacement of [3H]Flumazenil from cloned human GABA alpha-5-beta-3-gamma-2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50311059(3-chloro-9H-benzo[f]imidazo[1,5-a][1,2,4]triazolo[...)
Affinity DataKi:  6.40nMAssay Description:Displacement of [3H]Flumazenil from human GABA alpha-5-beta-3-gamma-2 receptor expressed in insect SF9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50311050(9H-benzo[f]imidazo[1,5-a][1,2,4]triazolo[1,5-d][1,...)
Affinity DataKi:  6.40nMAssay Description:Displacement of [3H]Flumazenil from human GABA alpha-5-beta-3-gamma-2 receptor expressed in insect SF9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50311070(3-methoxy-10-methyl-9H-benzo[f]imidazo[1,5-a][1,2,...)
Affinity DataKi:  7.70nMAssay Description:Displacement of [3H]Flumazenil from cloned human GABA alpha-5-beta-3-gamma-2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandPNGBDBM50311033(3-bromo-10-chloro-9H-benzo[f]imidazo[1,5-a][1,2,4]...)
Affinity DataKi:  8.80nMAssay Description:Displacement of [3H]Flumazenil from cloned human GABA alpha-3-beta-3-gamma-2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50311067(3,10-dimethyl-9H-benzo[f]imidazo[1,5-a][1,2,4]tria...)
Affinity DataKi:  9.20nMAssay Description:Displacement of [3H]Flumazenil from cloned human GABA alpha-5-beta-3-gamma-2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50311058(3-chloro-10-cyclopropyl-9H-benzo[f]imidazo[1,5-a][...)
Affinity DataKi:  9.40nMAssay Description:Displacement of [3H]Flumazenil from cloned human GABA alpha-5-beta-3-gamma-2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50311063(3-bromo-10-(1-methyl-1H-pyrazol-5-yl)-9H-benzo[f]i...)
Affinity DataKi:  9.70nMAssay Description:Displacement of [3H]Flumazenil from cloned human GABA alpha-5-beta-3-gamma-2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50311051(3-fluoro-9H-benzo[f]imidazo[1,5-a][1,2,4]triazolo[...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]Flumazenil from human GABA alpha-5-beta-3-gamma-2 receptor expressed in insect SF9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50311043(10-chloro-3-(1H-imidazol-1-yl)-9H-benzo[f]imidazo[...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]Flumazenil from cloned human GABA alpha-5-beta-3-gamma-2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandPNGBDBM50311047(Ro-4882224 | 3,10-dichloro-9H-benzo[f]imidazo[1,5-...)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]Flumazenil from cloned human GABA alpha-3-beta-3-gamma-2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandPNGBDBM50311047(Ro-4882224 | 3,10-dichloro-9H-benzo[f]imidazo[1,5-...)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]Flumazenil from cloned human GABA alpha-1-beta-3-gamma-2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50311041(N-(10-chloro-9H-benzo[f]imidazo[1,5-a][1,2,4]triaz...)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]Flumazenil from cloned human GABA alpha-5-beta-3-gamma-2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50311069(10-methyl-3-(trifluoromethyl)-9H-benzo[f]imidazo[1...)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]Flumazenil from cloned human GABA alpha-5-beta-3-gamma-2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandPNGBDBM50311046(3-chloro-10-methyl-9H-benzo[f]imidazo[1,5-a][1,2,4...)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]Flumazenil from cloned human GABA alpha-1-beta-3-gamma-2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50311047(Ro-4882224 | 3,10-dichloro-9H-benzo[f]imidazo[1,5-...)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]Flumazenil from cloned human GABA alpha-2-beta-3-gamma-2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50311033(3-bromo-10-chloro-9H-benzo[f]imidazo[1,5-a][1,2,4]...)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]Flumazenil from cloned human GABA alpha-2-beta-3-gamma-2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50311060(3-chloro-10-(6-methylpyridin-2-yl)-9H-benzo[f]imid...)
Affinity DataKi:  31nMAssay Description:Displacement of [3H]Flumazenil from cloned human GABA alpha-5-beta-3-gamma-2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandPNGBDBM50311033(3-bromo-10-chloro-9H-benzo[f]imidazo[1,5-a][1,2,4]...)
Affinity DataKi:  33nMAssay Description:Displacement of [3H]Flumazenil from cloned human GABA alpha-1-beta-3-gamma-2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandPNGBDBM50311044(3-chloro-10-(difluoromethyl)-9H-benzo[f]imidazo[1,...)
Affinity DataKi:  48nMAssay Description:Displacement of [3H]Flumazenil from cloned human GABA alpha-3-beta-3-gamma-2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50311072(10-methyl-3-(trifluoromethoxy)-9H-benzo[f]imidazo[...)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]Flumazenil from cloned human GABA alpha-5-beta-3-gamma-2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandPNGBDBM50311044(3-chloro-10-(difluoromethyl)-9H-benzo[f]imidazo[1,...)
Affinity DataKi:  53nMAssay Description:Displacement of [3H]Flumazenil from cloned human GABA alpha-1-beta-3-gamma-2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50311042(N-(10-chloro-9H-benzo[f]imidazo[1,5-a][1,2,4]triaz...)
Affinity DataKi:  54nMAssay Description:Displacement of [3H]Flumazenil from cloned human GABA alpha-5-beta-3-gamma-2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
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