Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50030622
TargetSerine/threonine-protein kinase Chk2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50299272(4-(6-(1H-indol-6-yloxy)-5-aminopyrazin-2-yl)-N-(py...)
Affinity DataIC50: 580nMAssay Description:Inhibition of recombinant CHK2 by [gamma-33P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50299273((R)-4-(6-(1H-indol-6-yloxy)-5-aminopyrazin-2-yl)-N...)
Affinity DataIC50: 610nMAssay Description:Inhibition of recombinant CHK2 by [gamma-33P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50299274(4-(6-(1H-indol-6-yloxy)-5-aminopyrazin-2-yl)-N-(pi...)
Affinity DataIC50: 800nMAssay Description:Inhibition of recombinant CHK2 by [gamma-33P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50299275(4-(6-(1H-indol-6-yloxy)-5-aminopyrazin-2-yl)-N-(pi...)
Affinity DataIC50: 890nMAssay Description:Inhibition of recombinant CHK2 by [gamma-33P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50299270(4-(6-(1H-indol-6-yloxy)-5-aminopyrazin-2-yl)-N-(py...)
Affinity DataIC50: 960nMAssay Description:Inhibition of recombinant CHK2 by [gamma-33P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50299271(4-(6-(1H-indol-6-yloxy)-5-aminopyrazin-2-yl)-N-(pi...)
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of recombinant CHK2 by [gamma-33P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50299276(4-(5-amino-6-(1-(2,6-dichlorophenyl)ethoxy)pyrazin...)
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of recombinant CHK2 by [gamma-33P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50299276(4-(5-amino-6-(1-(2,6-dichlorophenyl)ethoxy)pyrazin...)
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of recombinant MET by [gamma-33P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50299271(4-(6-(1H-indol-6-yloxy)-5-aminopyrazin-2-yl)-N-(pi...)
Affinity DataIC50: 3.33E+3nMAssay Description:Inhibition of recombinant MET by [gamma-33P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50299272(4-(6-(1H-indol-6-yloxy)-5-aminopyrazin-2-yl)-N-(py...)
Affinity DataIC50: 3.55E+3nMAssay Description:Inhibition of recombinant MET by [gamma-33P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50299270(4-(6-(1H-indol-6-yloxy)-5-aminopyrazin-2-yl)-N-(py...)
Affinity DataIC50: 4.27E+3nMAssay Description:Inhibition of recombinant MET by [gamma-33P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50299274(4-(6-(1H-indol-6-yloxy)-5-aminopyrazin-2-yl)-N-(pi...)
Affinity DataIC50: 5.52E+3nMAssay Description:Inhibition of recombinant MET by [gamma-33P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50299275(4-(6-(1H-indol-6-yloxy)-5-aminopyrazin-2-yl)-N-(pi...)
Affinity DataIC50: 7.09E+3nMAssay Description:Inhibition of recombinant MET by [gamma-33P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50299273((R)-4-(6-(1H-indol-6-yloxy)-5-aminopyrazin-2-yl)-N...)
Affinity DataIC50: 1.37E+4nMAssay Description:Inhibition of recombinant MET by [gamma-33P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed