Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50039094
TargetEstrogen receptor(Human)
Institute of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM17292([2,4,6,7-3H]-17beta-estradiol | [3H]-estradiol | 1...)
Affinity DataIC50: 12.5nMAssay Description:Displacement of [3H]17beta-estradiol from human ERalpha expressed in SF9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Institute of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311679((4bR,10bS,12aS)-8-hydroxy-12a-methyl-9-phenethyl-2...)
Affinity DataIC50: 15nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Institute of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311682((4bR,10bS,12aS)-8-hydroxy-12a-methyl-2,3,4,4a,5,6,...)
Affinity DataIC50: 30nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Institute of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311678((4bR,10bS,12aS)-9-allyl-8-hydroxy-12a-methyl-2,3,4...)
Affinity DataIC50: 32nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Institute of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311673((8R,9S,13S,14S,16S)-2-chloro-16-fluoro-3-hydroxy-1...)
Affinity DataIC50: 35nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Institute of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311667((8R,9S,13S,14S)-3-hydroxy-13-methyl-2-phenethyl-7,...)
Affinity DataIC50: 47nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Institute of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311666((8R,9S,13S,14S)-3-hydroxy-13-methyl-2-(phenylethyn...)
Affinity DataIC50: 56nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Institute of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311675((4bR,10bS,12aS)-9-bromo-8-hydroxy-12a-methyl-2,3,4...)
Affinity DataIC50: 73nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Institute of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311674((4bR,10bS,12aS)-9-chloro-8-hydroxy-12a-methyl-2,3,...)
Affinity DataIC50: 77nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Institute of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311677((4bR,10bS,12aS)-8-hydroxy-9-methoxy-12a-methyl-2,3...)
Affinity DataIC50: 85nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Institute of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311680((2R,4bR,10bS,12aS)-9-chloro-2-fluoro-8-hydroxy-12a...)
Affinity DataIC50: 87nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Institute of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311661((8R,9S,13S,14S)-2-Ethyl-3-hydroxy-13-methyl-6,7,8,...)
Affinity DataIC50: 89nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Institute of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM17289(folliculin | (1S,10R,11S,15S)-5-hydroxy-15-methylt...)
Affinity DataIC50: 96nMAssay Description:Displacement of [3H]17beta-estradiol from human ERalpha expressed in SF9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Institute of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311672((8R,9S,13S,14S,16R)-2-chloro-16-fluoro-3-hydroxy-1...)
Affinity DataIC50: 101nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Institute of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM17289(folliculin | (1S,10R,11S,15S)-5-hydroxy-15-methylt...)
Affinity DataIC50: 109nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Institute of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311663((8R,9S,13S,14S)-2-allyl-3-hydroxy-13-methyl-7,8,9,...)
Affinity DataIC50: 109nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Institute of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311671((8R,9S,13S,14S)-2-chloro-13-ethyl-3-hydroxy-7,8,9,...)
Affinity DataIC50: 121nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Institute of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311676((4bR,10bS,12aS)-8-hydroxy-9-iodo-12a-methyl-2,3,4,...)
Affinity DataIC50: 123nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Institute of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311681((2S,4bR,10bS,12aS)-9-chloro-2-fluoro-8-hydroxy-12a...)
Affinity DataIC50: 126nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Institute of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311658((8R,9S,13S,14S)-2-chloro-3-hydroxy-13-methyl-7,8,9...)
Affinity DataIC50: 140nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Institute of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311660((8R,9S,13S,14S)-3-hydroxy-13-methyl-17-oxo-7,8,9,1...)
Affinity DataIC50: 148nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Institute of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311669((13S,14S,15S)-3-Hydroxy-2-methoxy-13-methyl-7,11,1...)
Affinity DataIC50: 193nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Institute of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311662(2-methoxyestrone | (8R,9S,13S,14S)-3-hydroxy-2-met...)
Affinity DataIC50: 207nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Institute of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311665((8R,9S,13S,14S)-3-hydroxy-13-methyl-2-pentanoyl-7,...)
Affinity DataIC50: 218nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Institute of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311659((8R,9S,13S,14S)-2-bromo-3-hydroxy-13-methyl-7,8,9,...)
Affinity DataIC50: 233nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Institute of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311670((8R,9S,13S,14S)-3-hydroxy-2-methoxy-13-methyl-7,8,...)
Affinity DataIC50: 392nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Institute of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311664((8R,9S,13S,14S)-3-hydroxy-13-methyl-2-propyl-7,8,9...)
Affinity DataIC50: 545nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Institute of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311668((8R,9S,13S)-3-hydroxy-2-methoxy-13-methyl-7,8,9,11...)
Affinity DataIC50: 633nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Institute of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311674((4bR,10bS,12aS)-9-chloro-8-hydroxy-12a-methyl-2,3,...)
Affinity DataIC50: 770nMAssay Description:Displacement of [3H]17beta-estradiol from human ERalpha expressed in SF9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Institute of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311677((4bR,10bS,12aS)-8-hydroxy-9-methoxy-12a-methyl-2,3...)
Affinity DataIC50: 6.20E+3nMAssay Description:Displacement of [3H]17beta-estradiol from human ERalpha expressed in SF9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Institute of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311662(2-methoxyestrone | (8R,9S,13S,14S)-3-hydroxy-2-met...)
Affinity DataIC50: 1.10E+4nMAssay Description:Displacement of [3H]17beta-estradiol from human ERalpha expressed in SF9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed