Compile Data Set for Download or QSAR
Report error Found 46 Enz. Inhib. hit(s) with all data for entry = 50030863
TargetEpidermal growth factor receptor(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302986(6-(benzo[d][1,3]dioxol-5-yl)-N-(thiophen-2-ylmethy...)
Affinity DataKd:  230nMAssay Description:Binding affinity to EGFR assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK4(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM80396(cid_1893667 | (1E)-1-(3-ethyl-5-methoxy-1,3-benzot...)
Affinity DataKd:  30nMAssay Description:Binding affinity to Clk4 assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK3(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM80396(cid_1893667 | (1E)-1-(3-ethyl-5-methoxy-1,3-benzot...)
Affinity DataKd:  3.00E+3nMAssay Description:Binding affinity to Clk3 assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK2(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM80396(cid_1893667 | (1E)-1-(3-ethyl-5-methoxy-1,3-benzot...)
Affinity DataKd:  95nMAssay Description:Binding affinity to Clk2 assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM80396(cid_1893667 | (1E)-1-(3-ethyl-5-methoxy-1,3-benzot...)
Affinity DataKd:  19nMAssay Description:Binding affinity to Clk1 assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCasein kinase I isoform delta(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM80396(cid_1893667 | (1E)-1-(3-ethyl-5-methoxy-1,3-benzot...)
Affinity DataKd:  150nMAssay Description:Binding affinity to CSNK1D assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCasein kinase I isoform epsilon(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM80396(cid_1893667 | (1E)-1-(3-ethyl-5-methoxy-1,3-benzot...)
Affinity DataKd:  300nMAssay Description:Binding affinity to CSNK1E assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCasein kinase I isoform gamma-2(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM80396(cid_1893667 | (1E)-1-(3-ethyl-5-methoxy-1,3-benzot...)
Affinity DataKd:  270nMAssay Description:Binding affinity to CSNK1G2 assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCasein kinase I isoform gamma-3(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM80396(cid_1893667 | (1E)-1-(3-ethyl-5-methoxy-1,3-benzot...)
Affinity DataKd:  290nMAssay Description:Binding affinity to CSNK1G3 assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM80396(cid_1893667 | (1E)-1-(3-ethyl-5-methoxy-1,3-benzot...)
Affinity DataKd:  12nMAssay Description:Binding affinity to Dyrk1A assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM80396(cid_1893667 | (1E)-1-(3-ethyl-5-methoxy-1,3-benzot...)
Affinity DataKd:  130nMAssay Description:Binding affinity to Dyrk1B assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM80396(cid_1893667 | (1E)-1-(3-ethyl-5-methoxy-1,3-benzot...)
Affinity DataKd:  130nMAssay Description:Binding affinity to PIM1 assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-3(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM80396(cid_1893667 | (1E)-1-(3-ethyl-5-methoxy-1,3-benzot...)
Affinity DataKd:  280nMAssay Description:Binding affinity to PIM3 assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302986(6-(benzo[d][1,3]dioxol-5-yl)-N-(thiophen-2-ylmethy...)
Affinity DataKd:  37nMAssay Description:Binding affinity to Clk1 assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302986(6-(benzo[d][1,3]dioxol-5-yl)-N-(thiophen-2-ylmethy...)
Affinity DataKd:  430nMAssay Description:Binding affinity to Dyrk1B assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK2(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302986(6-(benzo[d][1,3]dioxol-5-yl)-N-(thiophen-2-ylmethy...)
Affinity DataKd:  680nMAssay Description:Binding affinity to Clk2 assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302986(6-(benzo[d][1,3]dioxol-5-yl)-N-(thiophen-2-ylmethy...)
Affinity DataKd:  27nMAssay Description:Binding affinity to Dyrk1A assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 19(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM80396(cid_1893667 | (1E)-1-(3-ethyl-5-methoxy-1,3-benzot...)
Affinity DataKd:  290nMAssay Description:Binding affinity to Ysk4 assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK4(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302986(6-(benzo[d][1,3]dioxol-5-yl)-N-(thiophen-2-ylmethy...)
Affinity DataKd:  50nMAssay Description:Binding affinity to Clk4 assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK3(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302986(6-(benzo[d][1,3]dioxol-5-yl)-N-(thiophen-2-ylmethy...)
Affinity DataKd:  470nMAssay Description:Binding affinity to Clk3 assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK4(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302986(6-(benzo[d][1,3]dioxol-5-yl)-N-(thiophen-2-ylmethy...)
Affinity DataIC50: 63nMAssay Description:Inhibition of Clk4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK4(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302984(6-(benzo[d][1,3]dioxol-5-yl)-N-(furan-3-ylmethyl)q...)
Affinity DataIC50: 63nMAssay Description:Inhibition of Clk4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK4(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302982(6-(benzo[d][1,3]dioxol-5-yl)-N-(pyridin-3-ylmethyl...)
Affinity DataIC50: 100nMAssay Description:Inhibition of Clk4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK4(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302994(6-(furan-2-yl)-N-(furan-3-ylmethyl)quinazolin-4-am...)
Affinity DataIC50: 111nMAssay Description:Inhibition of Clk4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK4(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302983(6-(benzo[d][1,3]dioxol-5-yl)-N-(3-fluorobenzyl)qui...)
Affinity DataIC50: 126nMAssay Description:Inhibition of Clk4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK4(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302981(6-(benzo[d][1,3]dioxol-5-yl)-N-(3-methylbenzyl)qui...)
Affinity DataIC50: 126nMAssay Description:Inhibition of Clk4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK4(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302993(N-(3-fluorobenzyl)-6-(furan-2-yl)quinazolin-4-amin...)
Affinity DataIC50: 141nMAssay Description:Inhibition of Clk4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK4(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302990(6-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-N-(thiophe...)
Affinity DataIC50: 141nMAssay Description:Inhibition of Clk4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK4(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50303000(6-(3,5-dimethylisoxazol-4-yl)-N-(thiophen-2-ylmeth...)
Affinity DataIC50: 158nMAssay Description:Inhibition of Clk4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK4(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302998(6-(3,5-dimethylisoxazol-4-yl)-N-(3-fluorobenzyl)qu...)
Affinity DataIC50: 178nMAssay Description:Inhibition of Clk4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK4(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302985(6-(benzo[d][1,3]dioxol-5-yl)-N-((4-methylthiophen-...)
Affinity DataIC50: 178nMAssay Description:Inhibition of Clk4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK4(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302991(6-(furan-2-yl)-N-(3-methylbenzyl)quinazolin-4-amin...)
Affinity DataIC50: 224nMAssay Description:Inhibition of Clk4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK4(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302995(6-(furan-2-yl)-N-(thiophen-2-ylmethyl)quinazolin-4...)
Affinity DataIC50: 250nMAssay Description:Inhibition of Clk4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK4(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302996(6-(3,5-dimethylisoxazol-4-yl)-N-(3-methylbenzyl)qu...)
Affinity DataIC50: 282nMAssay Description:Inhibition of Clk4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK4(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302988(6-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-N-(pyridin...)
Affinity DataIC50: 447nMAssay Description:Inhibition of Clk4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK4(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302999(6-(3,5-dimethylisoxazol-4-yl)-N-((4-methylthiophen...)
Affinity DataIC50: 501nMAssay Description:Inhibition of Clk4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK4(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302989(6-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-N-((4-meth...)
Affinity DataIC50: 501nMAssay Description:Inhibition of Clk4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK4(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302987(6-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-N-(3-methy...)
Affinity DataIC50: 631nMAssay Description:Inhibition of Clk4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK4(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302977(N-(3-fluorobenzyl)-6-(3-methoxyphenyl)quinazolin-4...)
Affinity DataIC50: 708nMAssay Description:Inhibition of Clk4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK4(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302992(6-(furan-2-yl)-N-(pyridin-3-ylmethyl)quinazolin-4-...)
Affinity DataIC50: 794nMAssay Description:Inhibition of Clk4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK4(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302997(6-(3,5-dimethylisoxazol-4-yl)-N-(pyridin-3-ylmethy...)
Affinity DataIC50: 891nMAssay Description:Inhibition of Clk4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK4(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302980(6-(3-methoxyphenyl)-N-(thiophen-2-ylmethyl)quinazo...)
Affinity DataIC50: 891nMAssay Description:Inhibition of Clk4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK4(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302979(6-(3-methoxyphenyl)-N-((4-methylthiophen-2-yl)meth...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Clk4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK4(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302978(N-(furan-3-ylmethyl)-6-(3-methoxyphenyl)quinazolin...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Clk4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK4(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302975(6-(3-methoxyphenyl)-N-(3-methylbenzyl)quinazolin-4...)
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of Clk4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK4(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302976(6-(3-methoxyphenyl)-N-(pyridin-3-ylmethyl)quinazol...)
Affinity DataIC50: 3.55E+3nMAssay Description:Inhibition of Clk4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed