Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50030867
TargetDickkopf-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303035(4-(4-(5-methylthiophen-2-yl)pyrimidin-2-ylamino)be...)
Affinity DataEC50:  7.80E+3nMAssay Description:Inhibition of Dkk1-mediated Wnt/beta-casein signaling in osteosarcoma cells assessed as potentiation of TCF-luciferase responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDickkopf-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303036(N-((1-(4-(naphthalen-2-yl)pyrimidin-2-yl)piperidin...)
Affinity DataEC50:  1.90E+3nMAssay Description:Inhibition of Dkk1-mediated Wnt/beta-casein signaling in osteosarcoma cells assessed as potentiation of TCF-luciferase responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDickkopf-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303037((1-(4-(naphthalen-2-yl)pyrimidin-2-yl)piperidin-4-...)
Affinity DataEC50:  630nMAssay Description:Inhibition of Dkk1-mediated Wnt/beta-casein signaling in osteosarcoma cells assessed as potentiation of TCF-luciferase responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDickkopf-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303038(1-(4-(naphthalen-2-yl)pyrimidin-2-yl)piperidin-4-a...)
Affinity DataEC50:  1.00E+3nMAssay Description:Inhibition of Dkk1-mediated Wnt/beta-casein signaling in osteosarcoma cells assessed as potentiation of TCF-luciferase responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDickkopf-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303039(4-(4-(naphthalen-2-yl)pyrimidin-2-ylamino)benzenes...)
Affinity DataEC50:  1.00E+3nMAssay Description:Inhibition of Dkk1-mediated Wnt/beta-casein signaling in osteosarcoma cells assessed as potentiation of TCF-luciferase responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDickkopf-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303040(4-(methyl(4-(5-methylthiophen-2-yl)pyrimidin-2-yl)...)
Affinity DataEC50:  9.80E+3nMAssay Description:Inhibition of Dkk1-mediated Wnt/beta-casein signaling in osteosarcoma cells assessed as potentiation of TCF-luciferase responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303035(4-(4-(5-methylthiophen-2-yl)pyrimidin-2-ylamino)be...)
Affinity DataIC50: 200nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303039(4-(4-(naphthalen-2-yl)pyrimidin-2-ylamino)benzenes...)
Affinity DataIC50: 310nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303036(N-((1-(4-(naphthalen-2-yl)pyrimidin-2-yl)piperidin...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303038(1-(4-(naphthalen-2-yl)pyrimidin-2-yl)piperidin-4-a...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303040(4-(methyl(4-(5-methylthiophen-2-yl)pyrimidin-2-yl)...)
Affinity DataIC50: 6.50E+4nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303037((1-(4-(naphthalen-2-yl)pyrimidin-2-yl)piperidin-4-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed