Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50039027
TargetCoagulation factor X(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50304619(2-(1-{(2S)-3-[(6-Chloronaphthalene-2-yl)sulfonyl]-...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human factor 10a by para-nitroanilide release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50270656(2-(1-(3-(6-chloronaphthalen-2-ylsulfonyl)propanoyl...)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of human factor 10a by para-nitroanilide release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50304620(2-(1-{3-[(6-Chloronaphthalene-2-yl)sulfonyl]propan...)
Affinity DataIC50: 8nMAssay Description:Inhibition of human factor 10a by para-nitroanilide release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50304621(2-(1-{(2R)-3-[(6-Chloronaphthalene-2-yl)sulfonyl]-...)
Affinity DataIC50: 21nMAssay Description:Inhibition of human factor 10a by para-nitroanilide release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50304622(2-(1-{3-[(6-Chloronaphthalene-2-yl)sulfonyl]-2-oxo...)
Affinity DataIC50: 930nMAssay Description:Inhibition of human factor 10a by para-nitroanilide release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50304623(3-(6-chloronaphthalen-2-ylsulfonyl)propanoic acid ...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human factor 10a by para-nitroanilide release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50378585(CHEMBL1627118)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human factor 10a by para-nitroanilide release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50304625(1-(4-aminopiperidin-1-yl)-3-(6-chloronaphthalen-2-...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human factor 10a by para-nitroanilide release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50304619(2-(1-{(2S)-3-[(6-Chloronaphthalene-2-yl)sulfonyl]-...)
Affinity DataKi:  1.90E+3nMAssay Description:Inhibition of human thrombin by para-nitroanilide release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50304620(2-(1-{3-[(6-Chloronaphthalene-2-yl)sulfonyl]propan...)
Affinity DataKi:  7.80E+3nMAssay Description:Inhibition of human thrombin by para-nitroanilide release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetPlasminogen(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50304619(2-(1-{(2S)-3-[(6-Chloronaphthalene-2-yl)sulfonyl]-...)
Affinity DataKi: >6.00E+4nMAssay Description:Inhibition of human plasmin by para-nitroanilide release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetPlasminogen(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50304620(2-(1-{3-[(6-Chloronaphthalene-2-yl)sulfonyl]propan...)
Affinity DataKi: >6.00E+4nMAssay Description:Inhibition of human plasmin by para-nitroanilide release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50304619(2-(1-{(2S)-3-[(6-Chloronaphthalene-2-yl)sulfonyl]-...)
Affinity DataKi: >6.00E+4nMAssay Description:Inhibition of human tissue plasminogen activator by para-nitroanilide release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50304620(2-(1-{3-[(6-Chloronaphthalene-2-yl)sulfonyl]propan...)
Affinity DataKi: >6.00E+4nMAssay Description:Inhibition of human tissue plasminogen activator by para-nitroanilide release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed