Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50030873
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300828(N-(2-{3-[(3-Fluorophenyl)sulfonyl]-1H-pyrrolo[2,3-...)
Affinity DataEC50:  7.30nMAssay Description:Agonist activity at human HT6 receptor expressed in human HeLa cells assessed as intracellular cAMP level by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300832(N,N-Dimethyl-N-{2-[3-(phenylsulfonyl)-1H-pyrrolo[2...)
Affinity DataEC50:  25nMAssay Description:Agonist activity at human HT6 receptor expressed in human HeLa cells assessed as intracellular cAMP level by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303162(1-(1-(2-(dimethylamino)ethyl)-3-(3-fluorophenylsul...)
Affinity DataIC50: 41nMAssay Description:Antagonistic activity at human HT6 receptor expressed in HeLa cells assessed as intracellular cAMP level by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303166(2-(3-(3-chlorophenylsulfonyl)-1H-pyrrolo[3,2-b]pyr...)
Affinity DataIC50: 197nMAssay Description:Antagonistic activity at human HT6 receptor expressed in HeLa cells assessed as intracellular cAMP level by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303164(1-(1-(2-(dimethylamino)ethyl)-3-(naphthalen-1-ylsu...)
Affinity DataIC50: 295nMAssay Description:Antagonistic activity at human HT6 receptor expressed in HeLa cells assessed as intracellular cAMP level by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303163(1-(3-(4-bromophenylsulfonyl)-1-(2-(dimethylamino)e...)
Affinity DataIC50: 385nMAssay Description:Antagonistic activity at human HT6 receptor expressed in HeLa cells assessed as intracellular cAMP level by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303165(2-(3-(3-fluorophenylsulfonyl)-1H-pyrrolo[3,2-b]pyr...)
Affinity DataIC50: 823nMAssay Description:Antagonistic activity at human HT6 receptor expressed in HeLa cells assessed as intracellular cAMP level by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303164(1-(1-(2-(dimethylamino)ethyl)-3-(naphthalen-1-ylsu...)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]LSD from human HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303163(1-(3-(4-bromophenylsulfonyl)-1-(2-(dimethylamino)e...)
Affinity DataKi:  3.90nMAssay Description:Displacement of [3H]LSD from human HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300828(N-(2-{3-[(3-Fluorophenyl)sulfonyl]-1H-pyrrolo[2,3-...)
Affinity DataKi:  4.90nMAssay Description:Displacement of [3H]LSD from human HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303162(1-(1-(2-(dimethylamino)ethyl)-3-(3-fluorophenylsul...)
Affinity DataKi:  11.3nMAssay Description:Displacement of [3H]LSD from human HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300832(N,N-Dimethyl-N-{2-[3-(phenylsulfonyl)-1H-pyrrolo[2...)
Affinity DataKi:  23nMAssay Description:Displacement of [3H]LSD from human HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303166(2-(3-(3-chlorophenylsulfonyl)-1H-pyrrolo[3,2-b]pyr...)
Affinity DataKi:  35nMAssay Description:Displacement of [3H]LSD from human HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303168(2-(3-(6-chloroimidazo[2,1-b]thiazol-5-ylsulfonyl)-...)
Affinity DataKi:  42nMAssay Description:Displacement of [3H]LSD from human HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303167(2-(3-(m-tolylsulfonyl)-1H-pyrrolo[3,2-b]pyridin-1-...)
Affinity DataKi:  46nMAssay Description:Displacement of [3H]LSD from human HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303161(1-(1-(2-(dimethylamino)ethyl)-3-(phenylsulfonyl)-1...)
Affinity DataKi:  56nMAssay Description:Displacement of [3H]LSD from human HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303165(2-(3-(3-fluorophenylsulfonyl)-1H-pyrrolo[3,2-b]pyr...)
Affinity DataKi:  76nMAssay Description:Displacement of [3H]LSD from human HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303159(2-(3-(3-fluorophenylsulfonyl)-1H-pyrrolo[3,2-b]pyr...)
Affinity DataKi:  200nMAssay Description:Displacement of [3H]LSD from human HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303160(2-(5-chloro-3-(phenylsulfonyl)-1H-pyrrolo[3,2-b]py...)
Affinity DataKi:  214nMAssay Description:Displacement of [3H]LSD from human HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303158(N,N-dimethyl-2-(3-(phenylsulfonyl)-1H-pyrrolo[3,2-...)
Affinity DataKi:  368nMAssay Description:Displacement of [3H]LSD from human HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed